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145 Possible Causes for Active Generalized Spikes and Polyspikes, Jerk-Locked Premyoclonus Spikes, Progressive Action Tremor

  • Benign Adult Familial Myoclonic Epilepsy

    Usually, myoclonic tremor is the presenting symptom, characterized by tremulous finger movements and myoclonic jerks of the limbs increased by action and posture.[uniprot.org] […] cortical spikes detected by the jerk-locked back-averaging) ( Ikeda et al., 1990 ).[academic.oup.com] The EEG shows generalized polyspike and spike-and-wave discharges, frequently precipitated by photic stimulation.[clinicalgate.com]

  • Generalized Clonic or Tonic-Clonic Seizures

    Other information is obtained from tests such as: EEG (electroencephalogram) : people with EGTCS have normal EEG background and generalized spike wave or polyspike wave activity[epilepsy.com] premyoclonus spikes Hand tremor Neuronal loss in central nervous system Cutaneous photosensitivity Hyperreflexia Heterogeneous Weight loss Dystonia Splenomegaly Thrombocytopenia[mendelian.co] […] callosum Muscular hypotonia Infantile onset Intellectual disability, moderate Intention tremor Progressive neurologic deterioration Absence seizures Nevus EEG abnormality Jerk-locked[mendelian.co]

    Missing: Progressive Action Tremor
  • Epilepsia Partialis Continua

    ) Cortical tremor is a form of rhythmic myoclonus, presenting as postural or action tremor in some patients with progressive myoclonus epilepsy (PME), 76, 77 in Angelman syndrome[clinicalgate.com] Jerk-locked back averaging (JLA) of magnetoencephalogram disclosed a spike preceding the jerk localized at the hand motor area, whereas JLA of electroencephalogram revealed[ncbi.nlm.nih.gov] The EEG shows generalized polyspike and spike-and-wave discharges, frequently precipitated by photic stimulation.[clinicalgate.com]

  • Epilepsy

    spike wave and polyspike wave activity.[brain.oxfordjournals.org] EEG recordings showed a variety of changes: generalized spike wave and polyspike wave activity, focal discharges, focal or diffuse slowing or were normal.[brain.oxfordjournals.org] EEG background was normal (1), showed diffuse (3) or focal slowing that was temporal (1) and in the left hemisphere (1), and showed focal (central, temporal) discharges or generalized[brain.oxfordjournals.org]

    Missing: Jerk-Locked Premyoclonus Spikes Progressive Action Tremor
  • Progressive Myoclonic Epilepsy Type 3

    , action myoclonus, infrequent generalized seizures, and ataxia) or with proteinuria that progresses to renal failure.[ 42 ] Despite severe neurologic disability due mainly[thieme-connect.com] The EEG is characterized by slowing of background activity and the presence of generalized spike-wave and polyspike-wave complexes and bursts of slow waves. 5 High-voltage[clinicalgate.com] The EEG showed slow background activity with generalised epileptiform discharges manifesting as spike/polyspike wave complexes of variable duration that persisted throughout[elsevier.es]

    Missing: Jerk-Locked Premyoclonus Spikes
  • Juvenile Myoclonic Epilepsy

    spike-polyspike and waves.[ncbi.nlm.nih.gov] We included patients with JME with a history of predominant myoclonic seizures and at least one diagnostic EEG with normal background activity and bursts of typical 3-Hz generalized[ncbi.nlm.nih.gov]

    Missing: Jerk-Locked Premyoclonus Spikes Progressive Action Tremor
  • Progressive Myoclonic Epilepsy Type 8

    ) Cortical tremor is a form of rhythmic myoclonus, presenting as postural or action tremor in some patients with progressive myoclonus epilepsy (PME), 76, 77 in Angelman syndrome[clinicalgate.com] The EEG showed slow background activity with generalised epileptiform discharges manifesting as spike/polyspike wave complexes of variable duration that persisted throughout[elsevier.es] […] been observed in some children with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke (MELAS). 75 Rhythmic High-Frequency Cortical Myoclonus (Cortical Tremor[clinicalgate.com]

    Missing: Jerk-Locked Premyoclonus Spikes
  • Idiopathic Generalized Epilepsy

    Other characteristic EEG features include polyspikes, polyspike-wave discharges, occipital intermittent rhythmic delta activity, and photoparoxysmal response.[ncbi.nlm.nih.gov] The abnormalities included generalized spike-wave and/or spike-polyspike morphology in majority.[annalsofian.org] We included patients with single or multiple generalised seizures, in whom at least one active EEG showing a generalised spike and wave or polyspike and wave pattern was obtained[jnnp.bmj.com]

    Missing: Jerk-Locked Premyoclonus Spikes Progressive Action Tremor
  • Unverricht-Lundborg Syndrome

    AMRF typically presents at ages 15 to 25 years either with neurologic symptoms (including tremor, action myoclonus, seizures, and ataxia) or with proteinuria that progresses[ncbi.nlm.nih.gov] ., mild ataxia) 4 Marked photosensitive, generalized spike‐and‐wave and polyspike‐and‐wave paroxysms in EEG ( Koskiniemi et al., 1974b ).[onlinelibrary.wiley.com] , slow spike, polyspike, and slow wave discharges of 1.5-2.5 Hz, as is seen in Lennox-Gastaut syndrome. [6] The interictal EEG shows a generalized slow spike-wave pattern,[emedicine.medscape.com]

    Missing: Jerk-Locked Premyoclonus Spikes
  • Lafora Disease

    Mutations of this gene cause a progressive myoclonus epilepsy called action myoclonus–renal failure characterized by adult and rarely late-teenage onset progressive tremor[doi.org] The EEG showed slow background activity with generalised epileptiform discharges manifesting as spike/polyspike wave complexes of variable duration that persisted throughout[elsevier.es] Intermittent light stimulation generated a photoparoxysmal response at low frequencies. Epileptic activity did not increase during stages of drowsiness.[elsevier.es]

    Missing: Jerk-Locked Premyoclonus Spikes