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19 Possible Causes for activity, myo inositol 1 phosphate, synthase

  • Polyphenol

    Enantiodivergence in small-molecule catalysis of asymmetric phosphorylation: concise total syntheses of the enantiomeric D- myo -inositol-1-phosphate and D- myo -inositol-[doi.org] How do they express their biological activity? Are they really valuable for disease prevention? Can they be used to develop new pharmaceutical drugs?[ncbi.nlm.nih.gov] ) increased lipid synthesis and expression of the sterol response element-binding protein 1 (SREBP 1) and its target enzymes, acetyl-CoA carboxylase (ACC) and fatty acid synthase[ncbi.nlm.nih.gov]

  • Clopidogrel

    Measurements of inositol phosphates Inositol phosphates were measured essentially as described. 35 36 Confluent cultures of cells in 12-well plates were labeled with 1 μCi[doi.org] Clopidogrel is inactive in vitro, and a hepatic biotransformation is necessary to express the full antiaggregating activity of the drug.[ncbi.nlm.nih.gov] Mechanism of selective inhibition of the inducible isoform of prostaglandin G/H synthase. .[doi.org]

  • Saccharomyces Cerevisiae

    D - myo -inositol 1-phosphate) 2 ( CHEBI:60449 ) has role Saccharomyces cerevisiae metabolite ( CHEBI:75772 ) mannose-1 D - myo -inositol 1-phosphate ( CHEBI:60448 ) has role[ebi.ac.uk] Because sulfate mimics the chemistry of a phosphate group, this structural data suggested that this groove represents the phosphoryl transfer active site.[ncbi.nlm.nih.gov] Abstract Cystathionine β-synthase (CBS) is a key regulator of sulfur amino acid metabolism, taking homocysteine from the methionine cycle to the biosynthesis of cysteine via[ncbi.nlm.nih.gov]

  • Carbachol

    -Inositol 1,3,4-tris-phosphate ammonium salt 1 Product Result Match Criteria: Description Linear Formula: C 6 H 15 O 15 P 3 · 6NH 3 Molecular Weight: 522.28 CAS Number: 93133[sigmaaldrich.com] This study demonstrated that c-Src 1) activity is necessary for [Ca(2 )]i inhibition of NHE3 activity, 2) activation occurs rapidly ( 1 min) after CCh treatment, 3) directly[ncbi.nlm.nih.gov] […] cytotoxic drug paclitaxel plus carbachol, a cholinergic agonist, at low doses, to induce death in breast tumor MCF-7 cells, via mAChR activation, and the role of nitric oxide synthase[ncbi.nlm.nih.gov]

  • Bipolar Disorder

    ., Greenberg, M. ( 2002 ) Myo-inositol-1-phosphate (MIP) synthase: a possible new target for antibipolar drugs . Bipolar Disord 4: 15 – 20 .[doi.org] Lastly, we address the pharmacological and psychosocial treatment implications of research on reward-related neural activation in bipolar disorder.[ncbi.nlm.nih.gov] One of the extensively studied underlying mechanisms for these pharmacological interventions is inhibition of intracellular signaling cascades associated with glycogen synthase[ncbi.nlm.nih.gov]

  • Honey

    Among the most common additives are: ammonium sulphate, potassium phosphate, magnesium chloride, citric acid, sodium citrate, biotin, pyridoxine, myo-inositol, calcium panthotenate[mdpi.com] These activities were compared to Manuka honey which is used as an alternative medicine.[ncbi.nlm.nih.gov] Comparison of Vmax values for flight muscle hexokinase, phosphofructokinase, citrate synthase, and cytochrome c oxidase with rates of carbon and O2 flux during flight reveal[doi.org]

  • Familial Hypercholesterolemia

    K07937 ADP-ribosylation factor 1 K07938 ADP-ribosylation factor 3 K07940 ADP-ribosylation factor 5 Compound C00035 GDP C00044 GTP C04549 1-Phosphatidyl-1D-myo-inositol 3-phosphate[genome.jp] Leucocyte activation markers CD11b and CD66b were determined by flow cytometry.[ncbi.nlm.nih.gov] Combination Ile278Thr and 68-bp insertion 0.099 Methylenetetrahydrofolate reductase C677T 0.322 Endothelial Function Nitric oxide synthase type 3 A( 922)G 0.366 C( 690)T[doi.org]

  • Glucomannan

    C01245 D-myo-Inositol 1,4,5-trisphosphate C01277 1-Phosphatidyl-1D-myo-inositol 4-phosphate C04549 1-Phosphatidyl-1D-myo-inositol 3-phosphate C00269 CDPdiacylglycerol C01177[aber.ac.uk] The sulfation of konjac glucomannan and its anti-HIV and blood anticoagulant activities were investigated.[ncbi.nlm.nih.gov] Furthermore, GM suppressed UVB-induced gene expression of pro-inflammatory markers including nuclear factor kappa B, inducible nitric oxide synthase, interleukins 8 and 1,[ncbi.nlm.nih.gov]

  • Spinocerebellar Ataxia Type 1

    Immunohistochemical staining and enzyme activity measurements show myo-inositol-1-phosphate synthase to be localized in the vasculature of brain. J.[doi.org] Glial activation occurred in the absence of neuronal death, suggesting that glial activation results from signals emanating from dysfunctional neurons.[ncbi.nlm.nih.gov] Here, we show that lack of ATXN1 expression induces early alterations in proteins involved in glycolysis [pyruvate kinase, muscle, isoform 1 protein (PKM-i1), citrate synthase[ncbi.nlm.nih.gov]

  • Coxiella Burnetii

    HARMEET KAUR, RAKESH KUMAR SHUKLA, GITANJALI YADAV, DEBASIS CHATTOPADHYAY and MANOJ MAJEE , Two divergent genes encoding L‐myoinositol 1phosphate synthase1 (CaMIPS1) and[doi.org] This study provides the first evidence of VASP manipulation by an intravacuolar bacterial pathogen via activation of PKA in human macrophages.[ncbi.nlm.nih.gov] Eleven chromosomal genes of C. burnetii that have been cloned and expressed in E. coli include gltA , the citrate synthase gene; sodB, the superoxide dismutase gene; htpA,[cabi.org]