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340 Possible Causes for activity, oxidase, sulfhydryl

  • Xanthinuria

    The residual xanthine oxidase from the parents exhibited normal kinetics with respect to hypoxanthine.[] Reversible conversion of xanthine dehydrogenase into oxidase occurs by sulfhydryl group oxidation, which results in loss of the NAD binding site.[] Xanthine dehydrogenase can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification, xanthine dehydrogenase catalyzes[]

  • Malignant Neoplasm

    Reduction of lysyl oxidase (LOX), a copper-dependent amine oxidase that catalyses the crosslinking of collagens, elastin, and fibrillin in the ECM [ 7 ] reduces matrix stiffening[] , ultimately, to affect dietary and physical activity patterns among Americans.[] […] repaired before it is irreversible by the recombination of radicals and dissipation of the associated energy, or it may be modified by agents such as molecular oxygen or sulfhydryl[]

  • Variegate Porphyria

    Variegate porphyria is characterized by a partial reduction in the activity of protoporphyrinogen oxidase.[] […] of clinical symptoms, excrete porphyrin metabolites in urine and stool similar to variegate porphyria, accompanied by a significant decrease of porphobilinogen deaminase activity[] To accomplish this, it requires a divalent zinc cation and an intact sulfhydryl group per subunit.[]

  • Idiopathic Pulmonary Fibrosis

    KEYWORDS: Collagen; Extracellular matrix; Idiopathic pulmonary fibrosis; Lysyl oxidase; Second harmonic generation[] Physical activity was assessed using a physical activity monitor.[] Glutathione (L-gamma-glutamyl-L-cysteinyl-glycine, GSH), a sulfhydryl-containing tripeptide produced by most mammalian cells, is an efficient scavenger of toxic oxidants,[]

  • Deficiency of Sulfite Oxidase

    Abstract Isolated sulfite oxidase (SO) deficiency is an autosomal recessively inherited inborn error of sulfur metabolism.[] The deficiencies can be diagnosed prenatally by monitoring sulfite oxidase activity in chorionic villus sampling (CVS) tissue.[] […] immediately after voiding is recommended [ Johnson & Duran 2001 , Tan et al 2005 ]. (2) False positive urinary sulfite results may be caused by: Drugs containing free aliphatic sulfhydryl[]

  • Mitochondrial Myopathy with Reversible Cytochrome C Oxidase Deficiency

    Reversible mitochondrial myopathy with cytochrome c oxidase deficiency.[] At the second biopsy at 44 months of age, the COX activity had increased to normal in the entire specimen.[] Briefly, the DRS consists of two essential components: the sulfhydryl oxidase Erv1 (homolog to human GFER) and the redox-regulated import receptor Mia40.[]

  • Allopurinol

    Other Review Article Pharmacological Reviews March 2006, 58 (1) 87-114; DOI: Abstract The prototypical xanthine oxidase (XO) inhibitor allopurinol, has been the cornerstone[] The anticancer activity of 4 was comparable to that of Tanespimycin (17-N-allylamino-17-demethoxy geldanamycin, 17-AAG) that inhibited the growth of BEL-7402 and SMMC-7221[] The enzyme can interconvert between xanthine dehydrogenase and xanthine oxidase activities through reversible sulfhydryl oxidation on specific cysteine residues.[]

  • Xanthinuria Type 1

    Allopurinol was metabolized to oxypurinol and pyrazinamide to 5-hydroxypyrazinamide in spite of no activity of xanthine oxidase, suggesting that aldehyde oxidase converted[] Abstract Two brothers with classical xanthinuria who lacked xanthine dehydrogenase activity were encountered.[] Reversible conversion of xanthine dehydrogenase into oxidase occurs by sulfhydryl group oxidation, which results in loss of the NAD binding site.[]

  • Alkaptonuria

    […] byproduct Homogentisate 1,2-dioxygenase deficiency alcaptonuria deficiency of homogentisicase ALKAPTONURIA; AKU Ochronosis, hereditary Hereditary ochronosis Homogentisic Acid Oxidase[] We investigated the degree of activation of the Hedgehog signaling pathway and how treatment with inhibitors of the receptor Smoothened (Smo) influenced Hedgehog activation[] It requires oxygen, ferrous iron, and sulfhydryl groups to open the ring of homogentisic acid. The condition is inherited as an autosomal recessive disease.[]

  • Mitochondrial Myopathy

    A pathogenic 15-base pair deletion in mitochondrial DNA-encoded cytochrome c oxidase subunit III results in the absence of functional cytochrome c oxidase.[] Long sinus pauses were documented, and an atrial pacemaker with an active-fixation lead was implanted.[] We previously documented, in human non-pathological muscle fibres, the expression of the augmenter of liver regeneration (ALR), a sulfhydryl oxidase enzyme, whose presence[]