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49 Possible Causes for Acute Hemolytic Anemia, Burr Cell, Thrombotic Thrombocytopenic Purpura

  • Hemolytic Uremic Syndrome

    ., schistocytes, burr cells, or helmet cells) on peripheral blood smear, AND Renal injury (acute onset) evidenced by either hematuria, proteinuria, or elevated creatinine[wwwn.cdc.gov] It is defined by the triad: acute hemolytic anemia thrombocytopenia acute renal failure The most frequent cause of HUS is a food-borne infection by Shiga toxin (also termed[hus-online.at] Thrombotic thrombocytopenic purpura associated with ticlopidine-Thrombotic Thrombocytopenic Purpura (TTP) 271 a review of 60 cases. Ann Intern Med 1998;128: 541–544.[doi.org]

  • HELLP Syndrome

    Burr cells Schistocytes Reticulocyte count – consider to evaluate for presence of hemolysis Liver enzymes AST – 2 times the upper reference limit meets criteria LDH – markedly[arupconsult.com] She also exhibited microangiopathic hemolytic anemia, thrombocytopenia, and elevated liver enzymes (consistent with HELLP syndrome).[ncbi.nlm.nih.gov] CONCLUSION: Thrombotic thrombocytopenic purpura can mimic HELLP syndrome late in gestation.[ncbi.nlm.nih.gov]

  • Microangiopathic Hemolytic Anemia

    - schistocytes, “burr cells”, “helmet cells” and “triangle cells”. 6.[slideshare.net] The patients presented with an acute onset of Coombs negative hemolytic anemia and fragmentocytes in the peripheral blood smear which are typical for MAHA.[ncbi.nlm.nih.gov] The similarity of the mother's illness to thrombotic thrombocytopenic purpura and of the daughter's to adult hemolytic uremic syndrome suggests that these diseases are variants[ncbi.nlm.nih.gov]

  • Cerebral Thrombotic Thrombocytopenic Purpura

    cells, helmet-shaped RBCs, normoblasts, reticulocytosis, unconjugated BR, Hb, hemosiderin, haptoglobin, proteinuria Management Corticosteroids, aspirin, dipyridamole, Igs[medical-dictionary.thefreedictionary.com] Investigations revealed evidence of thrombocytopenia, microangiopathic hemolytic anemia and acute kidney injury. MRV brain showed cerebral venus sinus thrombosis.[scopemed.org] KEYWORDS: Cerebral microbleeds; MRI; ischemic stroke; thrombotic thrombocytopenic purpura[ncbi.nlm.nih.gov]

  • Acquired Toxic Hemolytic Anemia

    Membrane Burr Cells (Echinocytes) Spur Cells (Acanthocytes) Stomatocytes: mouth-shaped area of central pallor Target Cells: due to decreased lecithin/cholesterol acyltransferase[mdnxs.com] hemolytic anemia.[annals.org] HUS is characterized by acute renal failure, microangiopathic hemolytic anemia, fever, and thrombocytopenia.[emjournal.net]

  • Uremic Anemia

    ., schistocytes, burr cells, or helmet cells) on peripheral blood smear, AND Renal injury (acute onset) evidenced by either hematuria, proteinuria, or elevated creatinine[wwwn.cdc.gov] [Hemolytic-uremic syndrome: bilateral necrosis of the renal cortex in acute acquired hemolytic anemia].[ahusallianceaction.org] Thrombotic thrombocytopenic purpura (similar to hemolytic-uremic syndrome ) involves nonimmunologic platelet destruction.[merckmanuals.com]

  • Paroxysmal Cold Hemoglobinuria

    RBC survival may be shortened in renal failure (burr cells) and in liver disease (acanthocytes and target cells).[med-ed.virginia.edu] Case presentation We report a case of an 18 year old female who presented in early pregnancy with acute hemolytic anemia and a positive Donath-Landsteiner antibody test.[bmchematol.biomedcentral.com] thrombocytopenic purpura; and Pharmacologic complement inhibitors.[books.google.com]

  • Atypical Hemolytic Uremic Syndrome

    A peripheral blood smear (PBS) was performed, which contained schistocytes (32%) with helmet and burr cells.[ncbi.nlm.nih.gov] It encompasses the clinical triad of thrombocytopenia, microangiopathic hemolytic anemia, and acute renal failure, without any association with Shiga toxins.[ncbi.nlm.nih.gov] Thrombotic thrombocytopenic purpura (TTP) and atypical hemolytic uremic syndrome (aHUS) are thrombotic microangiopathies (TMAs) that can present in pregnancy.[ncbi.nlm.nih.gov]

  • Acquired Spherocytosis

    Crenated / Burr cells / Echinocytes (Echinocytes, or burr cells or crenated red cells, in contrast, have shorter, sharp to blunt spicules of uniform length which are more[slideshare.net] This paper reports a case of acquired spherocytic hemolytic anemia recently observed in an elderly woman with acute cholecystitis and with C. welchii septicemia.Case ReportA[nejm.org] Red cell morphology: eg, haemolytic uraemic syndrome, thrombotic thrombocytopenic purpura.[patient.info]

  • Congenital Heinz Body Hemolytic Anemia

    Burr Cells: Liver disease Renal disease Severe burns Bleeding gastric ulcers Maybe artifact Echinocyte (Burr Cell) Acanthocyte vs Echinocyte Howell-Jelly: are intracellular[medical-labs.net] Acute hemolytic anemia caused by severe hypophosphatemia in diabetic ketoacidosis. Acta haematologica 1985; 73:55-7. Cappellini MD, Fiorelli GE.[japi.org] thrombocytopenic purpura ) Presence of a type of immature red blood cells called normoblasts may be due to: Cancer that has spread to bone marrow Blood disorder called erythroblastosis[m.ufhealth.org]

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