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52 Possible Causes for Acute Hemolytic Anemia, Congenital Nonspherocytic Hemolytic Anemia, Erythrocytes Decreased

  • Autoimmune Hemolytic Anemia

    Mechanisms of actions include suppression of autoantibody production, reduction in autoantibody affinity, and decreased destruction of erythrocytes by splenic macrophages,[doi.org] hemolytic anemia, that a revival of interest took place.[nejm.org] […] part of the body acute hemolytic anemia with the cold Physical exam splenomegaly jaundice Evaluation Two types of Coombs test direct (direct antiglobulin test, DAT) anti-IgG[medbullets.com]

  • Congenital Hemolytic Anemia

    HEREDITARY-FAMILY) ACUTE HEMOLYTIC ANEMIA CAUSED BY EXOGENOUS HEMOLYTIC FACTORS Acute hemolytic processes, accompanied by severe anemia and jaundice, occur in case of poisoning[en.medicine-guidebook.com] Phosphatidylserine internalization in erythrocytes with the mutant ATP11C was decreased 10-fold compared to that of the control, functionally establishing that ATP11C is a[ncbi.nlm.nih.gov] This group is sometimes called congenital nonspherocytic (hemolytic) anemia, which is a term for a congenital hemolytic anemia without spherocytosis, and usually excluding[en.wikipedia.org]

  • Pyruvate Kinase Deficiency

    Abstract Glucose-6-phosphate dehydrogenase (G6PD) deficiency can lead to acute hemolytic anemia, chronic nonspherocytic hemolytic anemia, and neonatal jaundice.[ncbi.nlm.nih.gov] decreased erythrocyte pyruvate kinase (PK) activity.[ncbi.nlm.nih.gov] In this later group of "congenital nonspherocytic hemolytic anemias" splenectomy has often been performed but usually does not produce a clinical cure.[nejm.org]

  • Glycogen Storage Disease Type 1

    Phk activity in erythrocytes was markedly decreased (12% residual activity) while the parents' erythrocyte Phk activities were in the heterozygote range (mother: 56%; father[academic.oup.com] Chronic hepatitis Albuminuria Distal renal tubular acidosis Hepatocellular adenoma Hypocitraturia Cataract Hyperreflexia Gait disturbance Full cheeks Carcinoma Elevated erythrocyte[mendelian.co] […] hypoplastic anemia Hyperkalemia Inflammation of the large intestine Intestinal obstruction Episodic fever Amyloidosis Antinuclear antibody positivity Acute hepatic failure Decreased[mendelian.co]

  • Toxic Hemolytic Anemia

    Abstract In 1937 Harvey and Janeway 1 first described acute hemolytic anemia as a toxic manifestation of sulfanilamide therapy. They presented three cases in adults.[annals.org] […] and the inability of bone marrow to compensate for the decreased life span.[diagnose-me.com] anemia Depending on the course, acute and chronic toxic hemolytic anemia is isolated.[m.iliveok.com]

  • Acquired Toxic Hemolytic Anemia

    hemolytic anemia.[annals.org] Premature destruction of red cells occurs through two primary mechanisms: (1) decreased erythrocyte deformability that leads to red-cell sequestration and extravascular haemolysis[oxfordmedicine.com] Congenital Nonspherocytic Hemolytic Anemia includes any of a group of inherited anemias characterized by shortened red cell survival, lack of spherocytosis, and normal osmotic[diagnose-me.com]

  • Hereditary Spherocytosis

    Acute hemolytic anemia as a presenting manifestation of Wilson's disease. J. Pediatr. 86 (1975), 245-247. 6. Crosby, W. H., and Conrad, M. E.[healio.com] Defects in these proteins lead to a loss in RBC membrane cohesion and membrane surface area, resulting in erythrocyte sphering, decreased deformability and premature destruction[orpha.net] The association between acute red blood cell aplasia and infection with parvovirus B19 is well described in patients with hereditary hemolytic anemia, particularly sickle[ncbi.nlm.nih.gov]

  • Traumatic Hemolytic Anemia

    Classification of Hemolytic Anemia Based on clinical presentation Acute Chronic Hemolytic anemia can be classified as inherited or acquired Based on site of Hemolysis Intravascular[medcaretips.com] […] and the inability of bone marrow to compensate for the decreased life span.[diagnose-me.com] Premature destruction of erythrocytes occurs intravascularly or extravascularly. The etiologies of hemolysis often are categorized as acquired or hereditary.[aafp.org]

  • Anemia due to Glutathione Metabolism Disorder

    Acute hemolytic anemia (AHA) Most G6PD deficiency patients are asymptomatic at baseline, but triggers can cause acute hemolytic anemia.[pathophys.org] Addition of copper to normal erythrocytes led to increased autohemolysis, thermolability of hemoglobin, increased sensitivity to acetylphenylhydrazine, decreased erythrocyte[annals.org] D58.9 ICD-10-CM Diagnosis Code D58.9 Hereditary hemolytic anemia, unspecified 2016 2017 2018 2019 Billable/Specific Code nonspherocytic congenital or hereditary NEC D55.8[icd10data.com]

  • Hemolytic Anemia due to a Disorder of Glycolytic Enzymes

    Defective PK catalysis in affected erythrocytes generally results in elevated concentrations of 2,3-diphosphoglycerate (2,3-DPG) and decreased ATP levels relative to cells[ommbid.mhmedical.com] The Acute Hemolytic Anemia can develop as a result of three types of triggers: (1) fava beans, (2) infections, and (3) drugs.[usmle.biochemistryformedics.com] Summary Epidemiology PK deficiency is the most frequent cause of congenital nonspherocytic hemolytic anemia with a prevalence estimated at 1/20,000 in the general white population[orpha.net]

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