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26 Possible Causes for Acute Hepatitis, Globulins Increased, Virus Associated Hemophagocytic Syndrome

  • Sickle Cell Disease

    We report four pediatric patients with hemoglobin SS disease with diverse manifestations of acute hepatic involvement including acute sickle hepatic crisis, hepatic sequestration[ncbi.nlm.nih.gov] INTRODUCTION: Hepatitis B virus infection attacks the liver and can cause both acute and chronic disease.[ncbi.nlm.nih.gov] The vaso-occlusive subphenotype is manifested clinically by self-limited pain (vaso-occlusive) episodes, acute chest syndrome (ACS), joint necrosis, stroke, acute splenic[web.archive.org]

  • Infectious Mononucleosis

    Here, we report two cases: the first case with acute hepatitis secondary to infectious mononucleosis and a second case, with acute hepatitis secondary to infectious mononucleosis[ncbi.nlm.nih.gov] , gamma globulin increased less frequently, and beta globulin, which was normal in practically all the cases of infectious mononucleosis, was increased in a considerable number[link.springer.com] Severe chronic active Epstein-Barr virus infection accompanied by virus-associated hemophagocytic syndrome, cerebellar ataxia and encephalitis.[emedicine.medscape.com]

  • Chronic Active Hepatitis B

    There was serological evidence of chronic active hepatitis B and acute hepatitis C virus infection.[ncbi.nlm.nih.gov] In all patients AST and ALT values returned to normal and there was a fall in serum delta GT and improvement of prothrombin time. an increase of globulins was noted.[ncbi.nlm.nih.gov] The positive anti-HCV antibody common in patients with IACAH is caused by disease related hypergammaglobulinemia and steroid therapy usually leads to decrease in gamma globulin[hepatitiscentral.com]

  • Chronic Active Hepatitis

    There was serological evidence of chronic active hepatitis B and acute hepatitis C virus infection.[ncbi.nlm.nih.gov] Severe chronic active hepatitis, defined as the presence of a fivefold increase in serum aminotransferases and a twofold rise in gamma globulin for at least 10 weeks, is considered[ncbi.nlm.nih.gov] The positive anti-HCV antibody common in patients with IACAH is caused by disease related hypergammaglobulinemia and steroid therapy usually leads to decrease in gamma globulin[hepatitiscentral.com]

  • Autoimmune Hepatitis

    Patients with known liver disease may present with acute hepatitis E and present a diagnostic challenge.[ncbi.nlm.nih.gov] More than 80% of affected individuals have increased gamma globulin in the blood.[hepatitiscentral.com] Virus-, drug- and lymphoma-associated hemophagocytic syndrome (HPS) was ruled out. Therefore, the patient was diagnosed with autoimmune-associated HPS (AAHS).[ncbi.nlm.nih.gov]

  • Erythema Infectiosum

    Acute hepatitis and benign myositis however are rarely reported in association with Parvovirus B19 infection.[ncbi.nlm.nih.gov] IV immune globulin has been used to curtail viremia and increase erythropoiesis in immunocompromised patients with pure RBC aplasia.[merckmanuals.com] Virus-associated hemophagocytic syndrome.[cmr.asm.org]

  • Hepatitis A

    Acute pancreatitis complicating acute hepatitis A is very rare especially in children.[ncbi.nlm.nih.gov] , which can help increase protection to HAV.[liverfoundation.org] hemophagocytic syndrome [3].[ncbi.nlm.nih.gov]

  • Lymphoma

    091.62 liver 091.62 lymphadenitis 091.4 meningitis, acute 091.81 mouth 091.3 mucous membranes 091.3 periosteum 091.61 periostitis 091.61 pharynx 091.3 relapse (treated) ([theodora.com] The erythrocyte sedimentation rate is a sign of activity of the disease and is caused by the increase of the a2-globulins and of the gamma globulins.[lecturio.com] Hodgkin lymphoma-associated hemophagocytic syndrome: a disorder strongly correlated with Epstein-Barr virus. Clin Infect Dis. 2008 Aug 15. 47(4):531-4. [Medline].[emedicine.medscape.com]

  • Hodgkin Lymphoma

    EBV-associated diseases [ edit ] Chronic active EBV infection Hodgkin's disease Acute renal failure [10] Alice in Wonderland syndrome Common variable immunodeficiency (CVID[en.wikipedia.org] Hodgkin lymphoma-associated hemophagocytic syndrome: a disorder strongly correlated with Epstein-Barr virus. Clin Infect Dis. 2008 Aug 15. 47(4):531-4. [Medline].[emedicine.medscape.com] ) Hairy leukoplakia Hepatitis Herpangina Infectious mononucleosis Kikuchi's disease Multiple Sclerosis (higher risk in patients infected as teenagers than as children) Nasopharyngeal[en.wikipedia.org]

  • Precursor-Cell Lymphoblastic Leukemia

    Acute leukemia with renal and hepatic mass with normal blood counts at presentation is a diagnostic challenge.[ncbi.nlm.nih.gov] Late-onset fatal Epstein-Barr virusassociated hemophagocytic syndrome following cord blood cell transplantation for adult acute lymphoblastic leukemia .[ajcp.oxfordjournals.org] Survival in untreated acute leukemia generally is 3 to 6 mo.[web.archive.org]

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