Possible Causes for acute intermittent porphyria Depression A depression in geology is a landform sunken or depressed below the surrounding area. Depressions form by various mechanisms. Erosion-related: Blowout: a depression created by wind erosion typically in either a partially vegetated sand dune ecosystem or dry soils (such as a post-glacial loess environment). Glacial[…] [en.wikipedia.org] Sunburn CONTEXT: The incidence of skin cancer, the most common type of cancer in the United States, is increasing. Sunburn is a major modifiable risk factor for skin cancer, and its prevalence among the US population is high. OBJECTIVES: To identify predictors of having had a red or painful sunburn in the past 12 months[…] [ncbi.nlm.nih.gov] Anxiety Disorder This review focuses on three HMD categories: acute, treatable HMDs (urea cycle abnormalities, remethylation disorders, acute intermittent porphyria); chronic, treatable HMDs [ncbi.nlm.nih.gov] View Article Google Scholar Kumar B: Acute intermittent porphyria presenting solely with psychosis: a case report and discussion. [dx.doi.org] Varied psychiatric manifestations of acute intermittent porphyria. Biol. [ncbi.nlm.nih.gov] Peripheral Neuropathy BACKGROUND: Even though chemotherapeutic regimens show considerable importance, it may cause progressive, continuing and sometimes irreversible peripheral neuropathy. Chemotherapy induced peripheral neuropathy (CIPN) is comprised of sensory abnormalities that are most distressing issues. The mechanism associated[…] [ncbi.nlm.nih.gov] Mental Disorder This review focuses on three HMD categories: acute, treatable HMDs (urea cycle abnormalities, remethylation disorders, acute intermittent porphyria); chronic, treatable HMDs [ncbi.nlm.nih.gov] View Article Google Scholar Kumar B: Acute intermittent porphyria presenting solely with psychosis: a case report and discussion. [dx.doi.org] "Acute Intermittent Porphyria (AIP)". American Porphyria Foundation. 18 February 2009. [en.wikipedia.org] Acute Pancreatitis acute intermittent porphyria and erythropoietic protoporphyria. [en.wikipedia.org] […] fold higher risk.[23] Less common causes include pancreatic cancer, pancreatic duct stones,[24] vasculitis (inflammation of the small blood vessels in the pancreas), and porphyria—particularly [en.wikipedia.org] Hepatocellular Carcinoma Screening for hepatocellular carcinoma in acute intermittent porphyria: a 15-year follow-up in northern Sweden. J Intern Med. 2011;269:538-45. 17. Mitchell EL, Khan Z. [hepatitisc.uw.edu] Acute and chronic hepatic porphyrias (acute intermittent porphyria, porphyria cutanea tarda, hereditary coproporphyria, variegate porphyria) and tyrosinemia type I are risk [en.wikipedia.org] intermittent porphyria. [ 10, 16, 17 ] Prognosis of Patients Diagnosed with HCC The overall prognosis for patients diagnosed with HCC in the United States has improved some [hepatitisc.uw.edu] Acute Intermittent Porphyria Acute intermittent porphyria. [ncbi.nlm.nih.gov] Acute intermittent porphyria Other names Swedish porphyria, pyrroloporphyria, intermittent acute porphyria Porphobilinogen Specialty Medical genetics Acute intermittent porphyria [en.wikipedia.org] Increased fecal porphyrins in acute intermittent porphyria. [ncbi.nlm.nih.gov] Acute Peritonitis Non-surgical disease - eg, myocardial infarction, pericarditis, pneumonia, sickle cell crisis, hepatitis, inflammatory bowel disease, opiate withdrawal, typhoid, acute intermittent [patient.info] porphyria, HIV-associated lymphadenopathy or enteritis. [patient.info] Acute urinary retention. Abdominal aortic aneurysm. Testicular torsion. [patient.info] Guillain-Barré Syndrome In South Africa (SA), a high incidence of variegate porphyria (VP) is seen as a result of a founder effect, but acute intermittent porphyria (AIP) is also encountered. [ncbi.nlm.nih.gov] […] hypophosphataemia Prolonged use of neuromuscular junction blocking drugs Tick paralysis West Nile poliomyelitis Acute intermittent porphyria Functional paralysisMFS, BBE, [vdocuments.net] There would be an initial presentation of neuromuscular junction disorder, acute intermittent porphyria, HIV infection, spinal cord disorders, toxic neuropathies and even [ncbi.nlm.nih.gov] General Anesthesia We report the successful management of general anesthesia for a patient with Pelizaeus-Merzbacher disease (PMD). PMD is one of a group of progressive, degenerative disorders of the cerebral white matter. The typical clinical manifestations of PMD include psychomotor retardation, nystagmus, abnormal muscle tone,[…] [ncbi.nlm.nih.gov] Porphyria Cimetidine may have a role in the treatment of acute intermittent porphyria by inhibiting heme oxidase activity, decreasing heme consumption, and inhibiting aminolevulinic [doi.org] What is acute intermittent porphyria? Acute intermittent porphyria is a rare genetic disorder that primarily affects the nervous system. [patientslikeme.com] Acute intermittent porphyria Other names Swedish porphyria, pyrroloporphyria, intermittent acute porphyria Porphobilinogen Specialty Medical genetics Acute intermittent porphyria [en.wikipedia.org] Acute Hepatic Porphyria the most common subtype of acute hepatic porphyria. [nature.com] INTRODUCTION Acute intermittent porphyria (AIP) is the most common and the most severe form of acute hepatic porphyria. [content.sciendo.com] Liver transplantation can cure acute intermittent porphyria. [merckmanuals.com] Familial Mediterranean Fever Appendicitis, intussusception, perforated peptic ulcer Hereditary angioedema Acute intermittent porphyria Relapsing pancreatitis Systemic lupus erythematosus and vasculitis [clevelandclinicmeded.com] Differential diagnosis 1 - Surgical emergencies as appendicitis, intussusception, perforated peptic ulcer, etc. 2 - in women, gynecologic disorders. 3 - Acute intermittent [slideshare.net] porphyria 4 - Relapsing pancreatitis 5 - Systemic lupus erythematosus and vasculitis 6 - Hypertriglyceridemia 7 - Abdominal epilepsy and abdominal migraine 8 - Other rare [slideshare.net] Porphyria Cutanea Tarda Lesson on Porphyria conditions: Porphyria Cutanea Tarda vs. Acute Intermittent Porphyria. [youtube.com] Primary porphyrias (hereditary enzyme defect) Hepatic porphyrias Acute hepatic porphyrias Acute intermittent porphyria (autosomal dominant) Porphyria variegata (autosomal [amboss.com] […] with abdominal symptoms and sometimes with neurologic lesions—a clinical picture similar to acute intermittent porphyria combined with light sensitivity. [annals.org] Peripheral Motor Neuropathy intermittent porphyria, lead poisoning, diphtheria, multifocal conduction block neuropathy Painful peripheral neuropathy “BADCAP” Diabetes mellitus Alcohol Vitamin B1 or [lifeinthefastlane.com] Predominantly Motor Neuropathies Guillain-Barre Sydnrome and CIPD Acute intermittant porphyria Lead neuropathy Heritable motor-sensory neuropathies Motor Neuron Disease (neuronopathy [enotes.tripod.com] intermittent porphyria Persisting nutritional deficiency Dominantly inherited sensory neuropathy CIDP Critical illness polyneuropathy Abnormal metabolic state CIDP HIV/AIDS [aafp.org] Paraplegia Spinal tuberculosis leading to paraplegia is uncommon in pregnancy and is a diagnostic and therapeutic challenge. We report a case of tubercular paraplegia presenting at 35 weeks of gestation. She was managed with Anti-tubercular drugs and did not require surgical intervention. Her neurological status improved and[…] [ncbi.nlm.nih.gov] Neurological Disorder Acute intermittent porphyria can give rise to acute psychosis, often in association with abdominal pain. [jnnp.bmj.com] Rasmussen Syndrome Seven years later, acute intermittent porphyria was diagnosed as she developed an acute episode of abdominal pain, dark urine, and hyponatremia. [ncbi.nlm.nih.gov] Acute intermittent porphyria and epilepsy: safety of clonazepam. Epilepsia. 1992 ;33: 108 - 111. [doi.org] and acute intermittent porphyria. [8] Diagnosis [ edit ] Brain MRI of an 8-year-old female with Rasmussen's encephalitis. [en.wikipedia.org] Hereditary Coproporphyria An acute, primarily motor neuropathy can occur in several forms of porphyria, including acute intermittent porphyria, variegate porphyria, and hereditary coproporphyria, sometimes [ncbi.nlm.nih.gov] An association between two types of acute hepatic porphyria (porphyria variegata and acute intermittent porphyria) and hepatocellular carcinoma has previously been reported [ncbi.nlm.nih.gov] Variegate Porphyria […] attacks in 10 patients with variegate porphyria and 87 attacks in 14 patients with acute intermittent porphyria. [ncbi.nlm.nih.gov] In most cases, the clinical findings are a combination of systemic symptoms similar to those occurring in acute intermittent porphyria and cutaneous lesions indistinguishable [ncbi.nlm.nih.gov] Desnick, RNAi-mediated silencing of hepatic Alas1 effectively prevents and treats the induced acute attacks in acute intermittent porphyria mice, Proceedings of the National [dx.doi.org] Hepatoerythropoietic Porphyria (rare in acute intermittent porphyria). [emedicine.medscape.com] Acute porphyrias include acute intermittent porphyria and ALAD deficiency porphyria. [ghr.nlm.nih.gov] acute intermittent porphyria ALAD-Deficiency Porphyria erythropoietic protoporphyria hepatoerythropoietic porphyria An autosomal recessive cutaneous porphyria that is due [rgd.mcw.edu] Erythropoietic Coproporphyria It later became evident that HCP could provoke acute attacks similar to those of acute intermittent porphyria (AIP) and variegate porphyria (VP). [ncbi.nlm.nih.gov] New form of dual porphyria: coexistent acute intermittent porphyria and porphyria cutanea tarda. Eur. J. Clin. [link.springer.com] Prenatal exclusion of congenital erythropoietic porphyria (Günther's disease) in a fetus at risk. Hum. Genet. 53 (1980) 217–221 Google Scholar Doss, M. [link.springer.com] Congenital Erythropoietic Porphyria Variegate porphyria is the most frequently encountered form of porphyria in South Africa, followed by porphyria cutanea tarda and acute intermittent porphyria. [porphyria-professionals.uct.ac.za] When symptoms occur, they can include acute attacks (similar to acute intermittent porphyria), skin damage, or both. [house.wikia.com] How is Acute Intermittent Porphyria diagnosed? [rarediseasesnetwork.org] Erythropoietic Protoporphyria In the past, elevation of ANA was reported in the cases of acute intermittent porphyria. [ncbi.nlm.nih.gov] Acute porphyrias include acute intermittent porphyria and ALAD deficiency porphyria. [ghr.nlm.nih.gov] Cimetidine has been shown to inhibit heme biosynthesis and results in symptomatic improvement in patients with acute intermittent porphyria (AIP) and porphyria cutanea tarda [ncbi.nlm.nih.gov] Ichthyosis Vulgaris Acute intermittent porphyria is rare before puberty, “as various reproductive hormones play [a] dominant role in the precipitation of acute attacks,” the researchers stated [porphyrianews.com] A rare case of acute intermittent porphyria with ichthyosis vulgaris in a young boy. [jfmpc.com] intermittent porphyria with ichthyosis vulgaris in a young boy. ( 29915773 ) Varshney G.A....Ghure U. 2018 4 Filaggrin gene polymorphisms in Iranian ichthyosis vulgaris and [malacards.org] Hereditary Thyroxine-Binding Globulin Deficiency intermittent porphyria, lymphoma, and hereditary TBG increase. [bestcarelab.com] […] liver disease, systemic illness ,acute intermittent porphyria, lymphocytic painless subacute thyroiditis, hereditary or idiopathic TBG excess, and medications such as methadone [perinatology.com] Acute intermittent porphyria : Serum TBG levels may be raised in acute intermittent porphyria. [lecturio.com] Syndrome of Inappropriate Antidiuretic Hormone Secretion We report an eighteen year old female, a case of acute intermittent porphyria with syndrome of inappropriate antidiuretic hormone secretion, as presenting feature for its [ncbi.nlm.nih.gov] A low activity of the porphobilinogen deaminase enzyme confirmed the diagnosis of acute intermittent porphyria. [ncbi.nlm.nih.gov] Nervous system disorders Acute psychosis Acute intermittent porphyria Brain abscess Cavernous sinus thrombosis Cerebellar and cerebral atrophy Cerebrovascular accident CNS [medcaretips.com] Prata-Libéral-Gonçalves Syndrome […] cutanea tarda, familial type Porphyria cutanea tarda, sporadic type Porphyria, acute intermittent Porphyria, congenital erythropoietic Porphyria, hereditary coproporphyria [mindmappedia.com] […] cutanea tarda, familial type Porphyria cutanea tarda, sporadic type Porphyria cutanea tarda Porphyria, acute intermittent Porphyria, Ala-D Porphyria, congenital erythropoietic [bioreference.net] Porphyria cutanea tarda, familial type[?] Porphyria cutanea tarda, sporadic type[?] Porphyria cutanea tarda[?] Porphyria, acute intermittent[?] Porphyria, Ala-D[?] [encyclopedia.kids.net.au] Nephrogenic Syndrome of Inappropriate Antidiuresis Adrenocortical and thyroid function and an acute intermittent porphyria screen were normal. [ncbi.nlm.nih.gov] […] levels (AVP); sequencing of AVPR2; and computed structural modelling of the wild‐type and constitutively activated mutant receptors.ResultsA 38‐year‐old man presented with intermittent [scipers.com] intermittent porphyria trauma, skull fracture * hydrocephalus cavernous sinus thrombosis psychiatric disorders infections Rocky Mountain spotted fever HIV1 infection, AIDS [anvita.info]
