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18 Possible Causes for Acute Intermittent Porphyria, Incidence of Hepatocellular Carcinoma Increased

  • Acute Intermittent Porphyria

    Acute intermittent porphyria.[ncbi.nlm.nih.gov] Acute intermittent porphyria is a metabolic disorder rarely seen in prepubertal children.[ncbi.nlm.nih.gov] Increased fecal porphyrins in acute intermittent porphyria.[ncbi.nlm.nih.gov]

  • Porphyria Cutanea Tarda

    […] together with abdominal symptoms and sometimes with neurologic lesions—a clinical picture similar to acute intermittent porphyria combined with light sensitivity.[annals.org] Acute intermittent porphyria is a dominant character. 3, 4 Dean and Barnes 5, 6 in South Africa have reported a familial incidence of patients showing light sensitivity,[annals.org] So-called congenital or erythropoietic 1 porphyria with severe light sensitivity is probably inherited as a recessive trait in man, and is certainly recessive in cattle. 2[annals.org]

  • Hepatocellular Carcinoma

    Screening for hepatocellular carcinoma in acute intermittent porphyria: a 15-year follow-up in northern Sweden. J Intern Med. 2011;269:538-45. 17. Mitchell EL, Khan Z.[hepatitisc.uw.edu] The incidence of hepatocellular carcinoma increased with serum HBV DNA level at study entry in a dose-response relationship ranging from 108 per 100,000 person-years for an[ncbi.nlm.nih.gov] The incidence of hepatocellular carcinoma (HCC) is increasing in western countries.[ncbi.nlm.nih.gov]

  • Porphyria

    carcinoma. [58] Patients with variegate porphyria have also shown increased incidences of hepatocellular carcinoma. [105] In patients with acute hepatic porphyria, Baravelli[emedicine.medscape.com] Cimetidine may have a role in the treatment of acute intermittent porphyria by inhibiting heme oxidase activity, decreasing heme consumption, and inhibiting aminolevulinic[doi.org] We identified the first molecularly confirmed acute intermittent porphyria in a black South African.[ncbi.nlm.nih.gov]

  • Acute Hepatic Porphyria

    Recent studies indicate that individuals with acute hepatic porphyria have a 36- to 61-fold increased risk of manifesting hepatocellular carcinoma.[medicaljournals.se] E80.1 Porphyria cutanea tarda E80.2 Other and unspecified porphyria E80.20 Unspecified porphyria E80.21 Acute intermittent (hepatic) porphyria E80.3 Defects of catalase and[icd10data.com] There were 184 patients with acute intermittent porphyria and 61 patients with variegate porphyria.[ncbi.nlm.nih.gov]

  • Variegate Porphyria

    […] attacks in 10 patients with variegate porphyria and 87 attacks in 14 patients with acute intermittent porphyria.[ncbi.nlm.nih.gov] Recent studies indicate that individuals with acute hepatic porphyria have a 36- to 61-fold increased risk of manifesting hepatocellular carcinoma.[ncbi.nlm.nih.gov] In most cases, the clinical findings are a combination of systemic symptoms similar to those occurring in acute intermittent porphyria and cutaneous lesions indistinguishable[ncbi.nlm.nih.gov]

  • Erythropoietic Coproporphyria

    Some patients with different types of porphyrias like AIP and ADP have an increased incidence of hepatocellular carcinoma (HCC).[clinicaladvisor.com] It later became evident that HCP could provoke acute attacks similar to those of acute intermittent porphyria (AIP) and variegate porphyria (VP).[ncbi.nlm.nih.gov] Several studies have shown increased incidences of diabetes, liver cirrhosis and hepatocellular carcinoma (20, 21, 27).[medicaljournals.se]

  • Hereditary Coproporphyria

    Some patients with different types of porphyrias like AIP and ADP have an increased incidence of hepatocellular carcinoma (HCC).[clinicaladvisor.com] An acute, primarily motor neuropathy can occur in several forms of porphyria, including acute intermittent porphyria, variegate porphyria, and hereditary coproporphyria, sometimes[ncbi.nlm.nih.gov] An association between two types of acute hepatic porphyria (porphyria variegata and acute intermittent porphyria) and hepatocellular carcinoma has previously been reported[ncbi.nlm.nih.gov]

  • Hepatoerythropoietic Porphyria

    (rare in acute intermittent porphyria).[emedicine.medscape.com] Some patients with different types of porphyrias like AIP and ADP have an increased incidence of hepatocellular carcinoma (HCC).[clinicaladvisor.com] Acute porphyrias include acute intermittent porphyria and ALAD deficiency porphyria.[ghr.nlm.nih.gov]

  • Tyrosinemia

    […] of hepatocellular carcinoma (HCC) increases substantially.[ncbi.nlm.nih.gov] Due to the biochemical and clinical resemblance of these neurological crises and acute intermittent porphyria, this group of symptoms in HTI patients is mostly called porphyria-like-syndrome[ncbi.nlm.nih.gov] Acute intermittent porphyria: a clinical and biochemical study of 46 patients . Medicine (Baltimore) 1970 ; 49: 1 –16. 27. Moore MR, Meredith PA.[nejm.org]

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