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25 Possible Causes for Acute Leukemia, Broad Nasal Bridge, Wide Space Between the First and Second Toe

  • Down Syndrome

    bridge, broad hands with short fingers, decreased muscle tone, and by trisomy of the human chromosome numbered 21 — called also trisomy 21 First Known Use of Down syndrome[merriam-webster.com] leukemia (AMKL) and 20 times more likely to develop acute lymphoblastic leukemia (ALL) than typical children.[ncbi.nlm.nih.gov] A wide space, often with a deep fissure between the first and second toes, is also common.[dx.doi.org]

  • Dubowitz Syndrome

    nasal bridge, dysplastic auricles, and retrognathia, is presented.[ncbi.nlm.nih.gov] […] lymphoblastic leukemia or neuroblastoma; see these terms).[orpha.net] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov]

  • Ring Chromosome 10

    bridge Broad nasal bridge Broad nasal root Broadened nasal bridge Increased breadth of bridge of nose Increased breadth of nasal bridge Increased width of bridge of nose[rarediseases.info.nih.gov] MLL is a frequent target for recurrent translocations in acute leukemia cases, which can be classified as acute myeloid leukemia (AML), acute lymphoblastic leukemia (ALL),[scielo.br] MalaCards based summary : Ring Chromosome 10, also known as ring chromosome 10 syndrome , is related to hirschsprung disease 2 and acute promyelocytic leukemia .[malacards.org]

  • Craniofrontonasal Dysplasia

    bridge Broad nasal bridge Broad nasal root Broadened nasal bridge Increased breadth of bridge of nose Increased breadth of nasal bridge Increased width of bridge of nose[rarediseases.info.nih.gov] We integrated the following cancer types: • Acute Myeloid Leukemia (TCGA, NEJM 2013) • Bladder Urothelial Carcinoma (TCGA, Nature 2014) • Breast Invasive Carcinoma (TCGA,[phosphosite.org] […] and broad nasal bridge.[mjdrdypu.org]

  • Atelosteogenesis Type 2

    Note dysplasia, scaphocephalic macrocephaly, coarse facial features, depressed nasal bridge, broad nasal tip, thick lips, short neck, protuberant abdomen, inguinal hernia,[thehealthscience.com] […] inflammatory demyelinating polyradiculoneuropathy Acute myeloblastic leukemia with maturation Acute myeloblastic leukemia without maturation Acute myelomonocytic leukemia[csbg.cnb.csic.es] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov]

  • Short Stature due to Endocrine Disorder

    bridge Broad nasal bridge Broad nasal root Broadened nasal bridge Increased breadth of bridge of nose Increased breadth of nasal bridge Increased width of bridge of nose[rarediseases.info.nih.gov] […] lymphoblastic leukemia.[karger.com] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov]

  • Weaver Syndrome

    nasal bridge, accentuated philtrum, micrognathia and large ears, and unique behavior characteristics with some social withdrawal.[ncbi.nlm.nih.gov] We report on a 4(1/2)-year-old girl with typical Weaver syndrome who developed acute lymphoblastic leukemia, an association not previously reported, and review the reported[ncbi.nlm.nih.gov] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov]

  • Kleiner Holmes Syndrome

    bridge; Choanal stenosis or atresia; Strabismus; Narrow palate; Cleft palate; Bifid uvula; Malocclusion; Delayed dental eruption; Ventricular septal defect; Overriding aorta[panelapp.genomicsengland.co.uk] […] myeloblastic leukemia type 1 Page 185 and 186: Adenocarcinoma of the urachus FCS s Page 187 and 188: nevus epibulbar dermoid mental reta Page 189 and 190: Agyria pachygyria[yumpu.com] […] gap between first and second toes Wide space between 1st, 2nd toes Wide space between first and second toes Widely spaced 1st-2nd toes Widely spaced first and second toes[rarediseases.info.nih.gov]

  • Baraitser Syndrome

    nasal bridge, and epicanthic folds.[pediatricneurosciences.com] Mutations in the PHF6 gene have been found in the cancer cells of people who have T-cell acute lymphoblastic leukaemia (T-ALL) or acute myelogenous leukemia (AML).[rarediseases.org] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov]

  • Familial Congenital Nasolacrimal Duct Obstruction

    […] flat nasal bridge, malformed ears, and short neck.[genome.jp] , Eosinophilic, Acute Leukemia, Erythroblastic, Acute Leukemia, Experimental Leukemia, Feline Leukemia, Hairy Cell Leukemia, Lymphocytic Leukemia, Lymphocytic, Acute Leukemia[medgene.med.harvard.edu] space between first and second toes (sandal toes) clinodactyly of the fifth finger All of these are found in individuals without DS.[medicalhomeportal.org]

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