Create issue ticket

16 Possible Causes for Acute Liver Failure, Dark Urine, Liver Biopsy showing Periportal Necrosis

  • Viral Hepatitis

    In the icteric phase, the patients develop jaundice, gastrointestinal disturbance, dark urine, gray-colored stools, right upper quadrant pain, and hepatomegaly.[symptoma.com] Parvovirus B19 may be the causative agent in some adult cases of acute non-A-E viral hepatitis and acute liver failure.[ncbi.nlm.nih.gov] Symptoms of acute (newly acquired) hepatitis include: fever, fatigue, loss of appetite, nausea, vomiting, abdominal/stomach pain, dark urine, clay-colored feces, joint pain[dph.georgia.gov]

  • Massive Hepatic Necrosis

    A, intraoperative (POD 0) wedge biopsy of the native liver showed massive hepatic necrosis and periportal ductular structure (HE, 200 ).[nature.com] Wilson's disease (hereditary copper accumulation) may infrequently present with acute liver failure.[en.wikipedia.org] She developed jaundice with dark urine and a tempera- ture of 103 F.[nap.edu]

  • Isoniazid Hepatitis

    Supportive care for acute liver failure and even liver transplantation may be required.[patient.info] These include any of the following: unexplained anorexia, nausea, vomiting, dark urine, icterus, rash, persistent paresthesias of the hands and feet, persistant fatigue, weakness[rxwiki.com] urine for several days 1 146 107 Liver transplant 29 Eczema Rare concurrent alcohol consumption Fatigue, nausea for 2 weeks then icterus, dark urine and jaundice for several[cdc.gov]

  • Hepatitis B

    liver failure.[ncbi.nlm.nih.gov] Geographical distribution Hepatitis B virus can cause an acute illness with symptoms that last several weeks, including yellowing of the skin and eyes (jaundice), dark urine[web.archive.org] Symptoms include fatigue, jaundice, nausea, vomiting, dark urine, light stools. Diagnosis is by blood test.[medicinenet.com]

  • Hepatitis A

    Hepatitis A related acute liver failure is rare, but is associated with a poor prognosis.[ncbi.nlm.nih.gov] Symptoms of the disease include mild fever, loss of appetite, nausea, fatigue, vomiting, diarrhea, abdominal pain and dark urine and jaundice.[nj.com] urine, jaundice, fever, headache, nausea, abdominal pain, and loss of appetite Duration of Illness Variable, from 2 weeks to 3 months What Do I Do?[foodsafety.gov]

  • Primary Sclerosing Cholangitis

    Dark urine, as a result of excretion of bile by-products into urine Anorexia, fatigue, malaise (general discomfort or unease), and abdominal pain Nutritional deficiencies,[dovemed.com] Finally, although unusual, PSC can present as acute liver failure.[ncbi.nlm.nih.gov] Additional symptoms include a general feeling of ill health (malaise); abdominal pain, especially the upper right portion of the abdomen; nausea; dark urine; light-colored[rarediseases.org]

  • Autoimmune Hepatitis

    In more severe cases, biopsy typically shows periportal necrosis with mononuclear cell infiltrates (piecemeal necrosis) accompanied by variable periportal fibrosis and bile[merckmanuals.com] Acute liver failure is a rare syndrome with high mortality and is often diagnosed late.[ncbi.nlm.nih.gov] urine.[txliver.com]

  • Drug-induced Cholestatic Hepatitis

    Liver biopsy showed prominent spotty necrosis and focal confluent necrosis. Portal and mild periportal lymphomononuclear inflammation.[jcdr.net] The clinical presentation of a patient with DILI can vary from an asymptomatic rise in liver enzymes to acute liver failure.[mdedge.com] The typical presentation of symptoms includes nausea, fatigue and pruritus followed by dark urine and jaundice .[livertox.nih.gov]

  • Hepatitis D

    A comparison of the first and third liver-biopsy specimens showed a significant reduction of portal inflammation (P 0.05) in patients treated with the higher dose of interferon[nejm.org] Complications may include: Chronic active hepatitis Acute liver failure Call your health care provider if you have symptoms of hepatitis B.[medlineplus.gov] urine and pale-coloured faeces.”[nuaa.org.au]

  • Chronic Hepatitis

    In more severe cases, biopsy typically shows periportal necrosis with mononuclear cell infiltrates (piecemeal necrosis) accompanied by variable periportal fibrosis and bile[merckmanuals.com] Clinical Features of Acute Liver Failure.[doi.org] Hepatitis symptoms can include: Fever Weakness Nausea, vomiting Headache Appetite loss Muscle aches, joint pains Drowsiness Dark urine Light-colored stools Abdominal discomfort[everydayhealth.com]

Similar symptoms