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22 Possible Causes for Acute Liver Failure, Liver Biopsy showing Periportal Necrosis

  • Massive Hepatic Necrosis

    A, intraoperative (POD 0) wedge biopsy of the native liver showed massive hepatic necrosis and periportal ductular structure (HE, 200 ).[] Wilson's disease (hereditary copper accumulation) may infrequently present with acute liver failure.[] […] necrosis of liver Approximate Synonyms Acute and subacute hepatic failure Acute hepatic failure Acute hepatic necrosis Acute hepatitis Acute liver failure Acute liver failure[]

  • Viral Hepatitis

    Parvovirus B19 may be the causative agent in some adult cases of acute non-A-E viral hepatitis and acute liver failure.[] The clinical spectrum of acute hepatitis A is wide, ranging from mild case without any noticeable symptoms to severe case with acute liver failure leading to mortality.[] Occasionally, acute viral hepatitis progresses to acute liver failure (indicating fulminant hepatitis).[]

  • Isoniazid Hepatitis

    Supportive care for acute liver failure and even liver transplantation may be required.[] […] acetaminophen-induced acute liver failure.[] Acute liver failure due to isoniazid.[]

  • Hepatitis B

    liver failure.[] The main indications for transplant owing to HBV are now acute liver failure (both acute and acute reactivation on the background of chronic HBV) and HCC.[] Severe acute hepatitis B can be treated with an oral antiviral drug but available data on effectiveness are conflicting and those with acute liver failure are candidates for[]

  • Hepatitis A

    Hepatitis A related acute liver failure is rare, but is associated with a poor prognosis.[] Therefore, he was diagnosed with severe acute liver failure with acute renal failure (ARF) caused by HAV infection.[] Late-onset hepatic failure, the least of the fulminant hepatic failures, has not occurred in patients with hepatitis A virus-related acute liver failure.[]

  • Aflatoxicosis

    OBJECTIVES: During January-June 2004, an aflatoxicosis outbreak in eastern Kenya resulted in 317 cases and 125 deaths. We conducted a case-control study to identify risk factors for contamination of implicated maize and, for the first time, quantitated biomarkers associated with acute aflatoxicosis. DESIGN: We[…][]

  • Primary Sclerosing Cholangitis

    Finally, although unusual, PSC can present as acute liver failure.[] Disease-Associated Acute-On-Chronic Liver Failure , Canadian Journal of Gastroenterology and Hepatology , 10.1155/2018/5108781 , 2018 , (1-7) , (2018) .[] Hepatic failure - orthotopic liver transplant is indicated for PSC patients with significant cirrhosis or liver failure .[]

  • Hepatitis D

    A comparison of the first and third liver-biopsy specimens showed a significant reduction of portal inflammation (P 0.05) in patients treated with the higher dose of interferon[] Complications may include: Chronic active hepatitis Acute liver failure Call your health care provider if you have symptoms of hepatitis B.[] failure).[]

  • Autoimmune Hepatitis

    In more severe cases, biopsy typically shows periportal necrosis with mononuclear cell infiltrates (piecemeal necrosis) accompanied by variable periportal fibrosis and bile[] Acute liver failure is a rare syndrome with high mortality and is often diagnosed late.[] According to this definition, patients with "acute-on-chronic" or "acute-on-cirrhosis" liver failure were excluded.[]

  • Drug-induced Cholestatic Hepatitis

    Liver biopsy showed prominent spotty necrosis and focal confluent necrosis. Portal and mild periportal lymphomononuclear inflammation.[] The clinical presentation of a patient with DILI can vary from an asymptomatic rise in liver enzymes to acute liver failure.[] Supportive care for acute liver failure and even liver transplantation may be required.[]

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