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20 Possible Causes for Addison's Disease, Complement C3 Decreased

  • Autoimmune Disease

    , scleroderma , Addison disease, vitiligo , pernicious anemia , glomerulonephritis, and pulmonary fibrosis .[medicinenet.com] Glomerulonephritis is a common feature of patients with complement deficiencies, particularly those affecting complement components C1, C2, C3, or C4.[primaryimmune.org] Common autoimmune disorders include: Addison's disease Celiac disease - sprue (gluten-sensitive enteropathy) Dermatomyositis Graves' disease Hashimoto's thyroiditis Multiple[web.archive.org]

  • Systemic Amyloidosis

    Serum complement C3 decreased in all patients given at least 1 mg of the antibody.[medpagetoday.com]

  • Vitiligo-Associated Autoimmune Disease

    Glomerulonephritis is a common feature of patients with complement deficiencies, particularly those affecting complement components C1, C2, C3, or C4.[primaryimmune.org] […] anemia, systemic lupus erythematosus, and Addison's disease.[ncbi.nlm.nih.gov] (particularly hypothyroidism), pernicious anaemia, Addison's disease, systemic lupus erythematosus, and probably inflammatory bowel disease.[ingentaconnect.com]

  • Vitiligo-Associated Multiple Autoimmune Disease

    […] anemia, systemic lupus erythematosus, and Addison's disease.[ncbi.nlm.nih.gov] Glomerulonephritis is a common feature of patients with complement deficiencies, particularly those affecting complement components C1, C2, C3, or C4.[primaryimmune.org] Autoimmune diseases associated with vitiligo: (1) autoimmune polyendocrinopathy, especially when Addison's disease and/or Grave's disease are present (2) rheumatoid arthritis[meducator3.net]

  • Premature Ovarian Failure

    PATIENT(S): A 30-year-old woman with autoimmune premature ovarian failure, Addison's disease, and ulcerative colitis.[ncbi.nlm.nih.gov] Antibodies against thyroglobulin, nuclear antigens, heart, tissue gluten, or increased levels of immunoglobulin (Ig)M, or decreased levels of complement C3 and C4 were significantly[ncbi.nlm.nih.gov] Premature ovarian failure in patients with autoimmune Addison's disease: clinical, genetic, and immunological evaluation . J. Clin. Endocrinol.[nature.com]

  • Hypothyroidism

    disease, hypoparathyroidism, and mucocutaneous candidiasis.[emedicine.com] Ten proteins were more abundant in the hypothyroid vs. euthyroid state: complement C2, serotransferrin, complement C3, Ig κ chain C region, α-1-antichymotrypsin, complement[ncbi.nlm.nih.gov] […] is inherited in an autosomal recessive manner. [17] Autoimmune polyendocrinopathy type I is caused by a mutation in the AIRE gene and is characterized by the presence of Addison[emedicine.com]

  • Chronic Glomerulonephritis

    IN THE classic description of the disease that bears his name, Addison presented no significant clinical evidence of renal disease in any of the 11 cases he reported.[nejm.org] (even more so than patients with DDD), while serum levels of components of the classical complement pathway (C4 and C1q) are normal or decreased mildly [ 8 ].[ndt.oxfordjournals.org] disease.[nejm.org]

  • Partial Acquired Lipodystrophy Associated with C3 Nephritic Factor

    FACTOR Classification unclassified Phenotypes Decreased serum complement C3 ; Hematuria ; Lipodystrophy ; Loss of subcutaneous adipose tissue from upper limbs ; Membranoproliferative[mousephenotype.org] Pernicious anaemia is associated with other autoimmune diseases, including Graves' disease, myxedema, thyroiditis, Addison’s disease, vitiligo, and hypoparathyroidism.[seals.health.nsw.gov.au] Complement factor H (CFH) binds to C3b and inhibits the binding of Factor B, thereby decreasing C3 convertase levels.3 Conversely, stabilizing proteins are also present, such[path.upmc.edu]

  • Oligomeganephronia

    . • Complement C3 is typically decreased in the acute phase and usually normalises within 6 - 12 weeks after the onset of the disease.[cmej.org.za] 著者 由井 郁子 YUI IKUKO 川崎市立川崎病院小児科 Department of Pediatrics, Kawasaki Municipal Hospital 抄録 A male Japanese baby weighing 2830g was born to a mother with Addison's disease, who[ci.nii.ac.jp] アジソン病 Addison’s disease, autoimmune adrenalitis アジソン病、自己免疫性副腎炎 1 不要 有 HPS2726 HPS2727 HPS2728 HPS2729 HPS2730 HPS2731 235.[cell.brc.riken.jp]

  • POEMS Syndrome

    From those with endocrinopathy, 36.7% had thyroid disease, 26.7% hypogonadism, 3.3% type 2 diabetes mellitus (2DM) and 6.5% Addison disease.[endocrine-abstracts.org] Laboratory studies revealed a further decrease of hemoglobin to 56 g/L. Serum IgA was elevated (5.39 g/L), IgG and complements C3, C4 were within normal range.[journals.lww.com] There is an increase in melanin production without an increase in the number of melanocytes , a process similar to that seen in Addison disease .[dermnetnz.org]

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