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65 Possible Causes for Adrenocorticotropin Deficiency

  • Autoimmune Hypophysitis

    Adrenocorticotropin deficiency was the most common (7/10) followed by thyroid stimulating hormone and gonadotropins (each in 5).[scopemed.org] Isolated adrenocorticotropin deficiency associated with an autoantibody to a corticotroph antigen that is not adrenocorticotropin or other proopiomelanocortin-derived peptides[link.springer.com] Deficient hormones were replaced and none of the patients were treated with immunosuppressive therapy or surgery.[scopemed.org]

  • Congenital Isolated ACTH Deficiency

    Otsuka F, Yamamoto K, Shimada N et al (2004) Cholestatic jaundice: an unusual symptom of isolated adrenocorticotropin deficiency in adults.[link.springer.com] Vallette-Kasic S, Brue T, Pulichino A-M, Gueydan M, Barlier A, et al. (2005) Congenital isolated adrenocorticotropin deficiency: an underestimated cause of neonatal death,[journals.plos.org] Vallette-Kasic S, Couture C et al (2007) The TPIT gene mutation M86R associated with isolated adrenocorticotropin deficiency interferes with protein: protein interactions.[link.springer.com]

  • Hyponatremia

    Low plasma bicarbonate level in hyponatremia related to adrenocorticotropin deficiency. J Clin Endocrinol Metab. 2003; 88 :5255–7. [ PubMed ] [ Google Scholar ] 35.[ncbi.nlm.nih.gov]

  • Polycystic Ovary Syndrome

    Abstract In cortisone reductase deficiency (CRD), activation of cortisone to cortisol does not occur, resulting in adrenocorticotropin-mediated androgen excess and a phenotype[doi.org]

  • Hypothyroidism

    Evaluation of thyroid function in patients with isolated adrenocorticotropin deficiency. Am J Med Sci 1992; 304: 279-284. 9.8.4.4. Abdullatif HD, Ashraf AP.[ncbi.nlm.nih.gov]

  • Graves Disease

    However, she suffered a further decrease in her serum cortisol level and was diagnosed with isolated adrenocorticotropin deficiency (IAD), in which bioinactive ACTH likely[ncbi.nlm.nih.gov]

  • Adrenal Insufficiency

    Alternatively, adrenal insufficiency can be caused by a deficiency of the adrenocorticotropin hormone (ACTH).[endocrineweb.com] […] growth hormone deficiency, FSH, follicle-stimulating hormone, LH, luteinizing hormone, adrenocorticotropin hormone, ACTH, prolactin, ADH, antidiuretic hormone, low hormones[webmd.com] Hereditary isolated glucocorticoid deficiency is associated with abnormalities of the adrenocorticotropin receptor gene. J Clin Invest. 1993 Nov. 92(5):2458-61.[emedicine.com]

  • Addison's Disease

    Treatment involves replacement of the deficient hormones.[ncbi.nlm.nih.gov] Alternatively, adrenal insufficiency can be caused by a deficiency of the adrenocorticotropin hormone (ACTH).[endocrineweb.com] Glucocorticoid deficiency with achalasia of the cardia and lack of lacrimation. Clin Endocrinol (Oxf) . Sep 1985;23(3):237-43. [Medline].[web.archive.org]

  • Adrenogenital Syndrome

    adrenocorticotropin (ACTH) and overproduces cortisol precursors.[medigoo.com] Owing to this loss of enzyme function, patients with 21-hydroxylase deficiency cannot synthesize cortisol efficiently, and as a result, the adrenal cortex is stimulated by[medigoo.com]

  • Hypopituitarism

    Adrenocorticotropin deficiency in combined pituitary hormone deficiency patients homozygous for a novel PROP1 deletion.[web.archive.org] Not enough adrenocorticotropin hormone. This is a rare deficiency. It leads to an underactive adrenal gland.[hopkinsmedicine.org] Congenital isolated adrenocorticotropin deficiency: an underestimated cause of neonatal death, explained by TPIT gene mutations.[web.archive.org]

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