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815 Possible Causes for Advanced Bone Age

  • Tuberculosis

    The study aims to evaluate the clinical efficacy of bilateral costotransverse debridement, transpedicular fixation, fusion, and local continuous chemotherapy in 20 patients of contiguous multisegmental thoracic spinal tuberculosis (CMTSTB). We analyzed 20 patients with contiguous thoracic spinal tuberculosis (TB) who[…][]

  • Lipodystrophy

    Advanced bone age and linear growth and skeletal muscle prominence can be seen during childhood.[] bone age, acanthosis nigricans and hirsutism. lip·o·dys·tro·phy ( lip'ō-dis'trō-fē ), 1.[] Patients with CGL can develop hyperphagia as a result of profound leptin deficiency in early childhood, and may have accelerated linear growth, advanced bone age and features[]

  • Gigantism

    Her precocious manifestations were public hair, acne vulgaris, hirsutism, and advanced bone age.[] The bone age is usually advanced so that the adult stature may be diminished.[] From two years of age she showed unusual overgrowth, and at 5 years old she was 133.5 cm ( 5.5 SD) tall and weighed 40.5 kg.[]

  • Weaver Syndrome

    Accelerated growth and advanced bone age are consistent findings in Weaver-Smith syndrome (WSS).[] In addition to the characteristic manifestations of overgrowth and advanced bone age, the facies were typical, with a broad forehead, hypertelorism, a long philtrum, micrognathia[] Weaver syndrome is a rare disorder of unknown etiology characterized by skeletal overgrowth, distinctive craniofacial and digital abnormalities, and advanced bone age.[]

  • Marshall-Smith Syndrome

    The causes of advanced bone age in this syndrome are also reviewed. Additionally, the patient showed progressive dilatation of the aortic root.[] Marshall-Smith syndrome is characterized by advanced bone age, failure to thrive, respiratory problems, dysmorphic facial features, and variable mental retardation.[] Marshall-Smith syndrome is a rare congenital condition, characterized by advanced bone age, facial anomalies and relative failure to thrive.[]

  • Generalized Lipodystrophy

    It is characterized by a lack of adipose tissue throughout the body from birth, muscular hypertrophy, advanced bone age, fatty liver, and insulin resistance.[] The clinical phenotype, viz. lack of subcutaneous fat, hepatosplenomegaly, cardiomegaly, and advanced bone age was also documented.[] Advanced bone age and linear growth and skeletal muscle prominence can be seen during childhood.[]

  • Sotos Syndrome

    Facial gestalt and macrocephaly, rather than advanced bone age, are the strongest indications for clinical diagnosis.[] Of these 18 children, 3 (17%) had an advanced bone age and were diagnosed with Sotos syndrome.[] On bone radiography, most patients will have advanced bone age although this is not a specific test as some patients will have appropriate bone age or delayed growth.[]

  • Alstrom Syndrome

    One additional manifestation not described widely in the literature, advanced bone age, was observed in all subjects tested.[] bone age 15 years – adulthood 2 major and 2 minor criteria or 1 major and 4 minor criteria.[] Criteria Obesity and/or insulin resistance and/or Type 2 Diabetes History of dilated cardiomyopathy with congestive heart failure Hearing loss Hepatic dysfunction Renal failure Advanced[]

  • Acrodysostosis Type 1

    Individuals often have advanced bone age, may be obese and some are resistant to multiple hormones including parathyroid, calcitonin and growth hormone releasing hormone.[] ACRDYS1 is caused by heterozygous mutation in the PRKAR1A gene and is characterized by short stature, severe brachydactyly, facial dysostosis, nasal hypoplasia, advanced bone[] Very frequent - Abnormal vertebral size / shape - Advanced bone age - Broad nose / nasal bridge - Cone epiphyses / epiphysis - Depressed nasal bridge - Flattened nose - Hypoplastic[]

  • Metaphyseal Acroscyphodysplasia

    bone age Early bone maturation [ more ] 0005616 Brachydactyly Short fingers or toes 0001156 Cone-shaped metacarpal epiphyses Cone-shaped end part of long bone 0006059 Coxa[] , advanced bone age and complete alopecia (5).[] Showing of 40 80%-99% of people have these symptoms Abnormality of the metaphysis Abnormality of the wide portion of a long bone 0000944 Accelerated skeletal maturation Advanced[]

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