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144 Possible Causes for Advanced Bone Age, Short Stature in Children

  • Adrenogenital Syndrome

    Advanced bone age may be diagnosed employing plain radiography. In patients with ambiguous genitalia, karyotyping should be carried out.[symptoma.com]

  • Pseudohypoparathyroidism

    We report three cases of primary osteoma cutis in children, two of whom (siblings) were associated with Albright's hereditary osteodystrophy (AHO), manifesting as short stature[ncbi.nlm.nih.gov]

  • Growth Hormone Deficiency

    Surprisingly, at 10.8 years, his bone age had advanced to 13 years, but physical exam, LH and testosterone levels remained prepubertal.[ncbi.nlm.nih.gov] Short stature is one of the clinical manifestations in these children.[ncbi.nlm.nih.gov] This can result in noticeably short stature in children.[childrenshospital.org]

  • Skeletal Dysplasia

    Advanced bone age, increased stature and irregular epiphyseal ossification with stippling of the main long bones were documented.[ncbi.nlm.nih.gov] Skeletal dysplasias are a group of genetic disorders characterized by short stature. They are frequently associated with a range of orthopaedic problems.[muhealth.org] With advancing age, platyspondyly became less conspicuous along with the development of thoracolumbar gibbus, the long bones showed dumbbell deformity and fluffy mega-epiphyses[jmg.bmj.com]

  • Russell-Silver Syndrome

    They also have characteristics of abnormal growth hormone pulsatility, absence of catch-down growth after growth hormone therapy and inappropriate advancement of bone age[ncbi.nlm.nih.gov] Russell-Silver syndrome (RSS) is characterized by slow growth both in utero and after birth, short stature, and specific facial features.[gemssforschools.org] Mean bone age advancement was 3.1 years after 3 years of treatment, and 6.0 years after 5 years treatment.[ncbi.nlm.nih.gov]

  • Osteogenesis Imperfecta

    The course is progressive, but many patients live to an advanced age.[whonamedit.com] Despite numerous fractures, restricted activity, and short stature, most adults and children with OI lead productive and successful lives.[checkorphan.org] Muscle mass is decreased in OI, even when short stature is taken into account.[ncbi.nlm.nih.gov]

  • Turner Syndrome

    There was no negative impact on growth course and bone age advancement nor on BMI in LE group.[ncbi.nlm.nih.gov] Stature on Children and Adolescents » Download a printable version of the Frequently Asked Questions when Beginning Growth Hormone Therapy brochure » Click here for member[magicfoundation.org] GH increases the rate of growth in most girls with Turner Syndrome without advancing the bone age.[turnersyndrome.co.nz]

  • Septo-Optic Dysplasia

    Marshall-Smith syndrome is characterized by advanced bone age, failure to thrive, respiratory problems, dysmorphic facial features, and variable mental retardation.[ncbi.nlm.nih.gov] Compared to other children referred for evaluation of short stature, children with SOD were younger (mean age 3.7 /- 3.6 vs 8.6 /- 4.9 years), had less severe short stature[ncbi.nlm.nih.gov] Her bone age at 9 years and 2 months was advanced (Japanese TW2 method, bone age of 10 years and 8 months). Her morning urine specific gravity was 1.010.[omicsonline.org]

  • Cushing's Disease

    Bone age had also advanced from 6.5 yr (at chronological age 8.5 yr) to 9.9 yr.[doi.org] It usually manifests as endocrinological deficits such as short stature, delayed puberty, and obesity.[ncbi.nlm.nih.gov] In one male patient, who was prepubertal at the time of RT, puberty occurred early, at age 9.8 yr (2 yr post RT), with genital development stage 2, pubic hair stage 2, and[doi.org]

  • Shwachman Syndrome

    […] marrow dysfunction. 3 - 5 Several studies have shown that, with advancing age, 40% to 60% of patients become pancreatic sufficient.[bloodjournal.org] stature.[dbpedia.org] Many children with this disease are short in stature and speech delays and slow development of motor skills are also common.[seattlecca.org]

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