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39 Possible Causes for Affected Females Have Been Reported, Arthralgia, Hematemesis

  • Hemophilia

    Although many hemophilia B carrier females do not have symptoms, an estimated 10-25% will develop mild symptoms and females have also been reported with moderate and severe[rarediseases.org] The most common adverse reactions reported (incidence 10%) were injection site reactions, headache, and arthralgia.[fda.gov] […] involvement include: • Fever • Abdominal distention and pain • Melena (bloody stool) • Hip flexion contracture (iliopsoas muscle spasm due to retroperitoneal hemorrhage) • Hematemesis[physio-pedia.com]

  • Factor VII Deficiency

    Although FVII gene mutations are extremely heterogeneous, several recurrent mutations have been reported, a few of them relatively frequent.[ncbi.nlm.nih.gov] Bleeding isolated to a single organ or system (eg, hematuria, hematemesis, hemoptysis) is less likely to be due to a hemostatic abnormality than to a local cause such as neoplasm[emedicine.medscape.com] In females, menorrhagia is prevalent and affects two thirds of the patients of fertile age.[ncbi.nlm.nih.gov]

  • Hemophilia B

    Thus the vast majority of affected individuals are males although rare females have been reported.[wohproject.org] Tingling, cracking, warmth, pain, stiffness, and refusal to use joint (children) CNS - Headache, stiff neck, vomiting, lethargy, irritability, and spinal cord syndromes GI - Hematemesis[emedicine.medscape.com] Approximately four cases have been reported in the medical literature.[rarediseases.org]

  • Henoch-Schönlein Purpura

    Although most studies have shown a male preponderance [ 8 , 12 – 15 ], but there are reports where greater number of females has been found to be affected [ 16 , 17 ].[ped-rheum.biomedcentral.com] She initially presented with arthralgia and murmur. Echocardiography showed mild to moderate mitral regurgitation.[ncbi.nlm.nih.gov] Severe abdominal pain with hematemesis developed, along with an increase in liver aminotransferase levels. Henoch–Schönlein purpura was suspected.[nejm.org]

  • Cutaneous Leukocytoclastic Vasculitis

    It has been further reported that almost half of all patients presenting with cutaneous vasculitis have self-limited disease localized to the skin without any attributable[ispub.com] The patient sought emergency treatment presenting with headache, arthralgia, cutaneous rash, and weight loss (4 kg) in the last 20 days.[ncbi.nlm.nih.gov] […] hemangiofibroma【血管線維腫】 *hemangioma【血管腫 毛細血管腫】 racemose hemangioma【蔓状血管腫】 *hemangiomatosis【血管腫症】 *hemangiopericytoma【血管外皮細胞腫】 *hemangiosarcoma【血管肉腫】 *hemarthrosis【関節出血 出血性関節症】 *hematemesis[medo.jp]

  • Mucopolysaccharidosis 2

    It is an X-linked recessive condition and expected to be found in males, but on rare occasions, affected females have been reported.[symptoma.com] Symptoms can include abdominal pain and vomiting of blood (hematemesis). Lesions can develop that cause a hole to form in the stomach or intestines (perforation).[rarediseases.org] In extremely rare cases, affected females have been reported. The incidence of Hunter syndrome is estimated at one in 100,000-150,000 male births.[rarediseases.org]

  • Primary Biliary Cirrhosis

    The disease primarily affects women over 40 years of age (female preponderance (9–10 1), although younger patients have been diagnosed, including children [2].[journals.plos.org] We report the case of a 53-year-old patient who presented with weakness, myalgia, arthralgia, shortness of breath and purpura.[ncbi.nlm.nih.gov] It has a lengthy latent period, usually followed by the sudden appearance of abdominal pain and swelling, hematemesis, dependent edema, or jaundice.[medical-dictionary.thefreedictionary.com]

  • Vasculitis

    Summary Epidemiology Prevalence is unknown but less than 200 cases have been reported in the literature.[orpha.net] Abstract IgA vasculitis (IgAV) commonly occurs in young children, who present with a tetrad of purpura, abdominal pain, arthralgia and nephritis.[ncbi.nlm.nih.gov] Severe abdominal pain, melena, or hematemesis usually responds promptly to 1 mg / kg / day of prednisone, which should not be continued longer than 2 weeks.[lupusinternational.com]

  • Necrotizing Vasculitis

    In the last decades, multiple cases of PTU causing antineutrophilic cytoplasmic antibody have been reported, some of them fatal.[ncbi.nlm.nih.gov] Within 14 days of interferon-alpha therapy (3 x 3 million IU/ml/week), purpuric skin lesions disappeared as well as fatigue and arthralgia; 9 months after initiation of therapy[ncbi.nlm.nih.gov] Severe abdominal pain, melena, or hematemesis usually responds promptly to 1 mg / kg / day of prednisone, which should not be continued longer than 2 weeks.[lupusinternational.com]

  • Measles

    A significant association between prepubescent mumps in females and infertility has been reported; it has been suggested that oophoritis might have resulted in a disturbance[cdc.gov] […] pathogens identified Known pathogen in birds; tested in virotherapy for certain malignancies Chikungunya Togaviridae SOT Fever, headache, abdominal pain; no arthritis or arthralgia[doi.org] Mastitis was included in case reports ( 99, 100 ) but also was described in a 1956–1957 outbreak as affecting 31% of postpubertal females ( 87 ).[cdc.gov]

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