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36 Possible Causes for Affected Females Have Been Reported, Epistaxis, Hematemesis

  • Hemophilia

    Recurrent, heavy nosebleeds, or epistaxis, without apparent cause are another symptom. Minor cuts that don’t clot or that stop and then start again also can occur.[hemophilia.org] Although many hemophilia B carrier females do not have symptoms, an estimated 10-25% will develop mild symptoms and females have also been reported with moderate and severe[rarediseases.org] […] involvement include: • Fever • Abdominal distention and pain • Melena (bloody stool) • Hip flexion contracture (iliopsoas muscle spasm due to retroperitoneal hemorrhage) • Hematemesis[physio-pedia.com]

  • Factor VII Deficiency

    FVIID was diagnosed for the first time in a 23-year-old pregnant woman at the 24th week of gestation due to complaint of intermittent epistaxis.[ncbi.nlm.nih.gov] Although FVII gene mutations are extremely heterogeneous, several recurrent mutations have been reported, a few of them relatively frequent.[ncbi.nlm.nih.gov] Bleeding isolated to a single organ or system (eg, hematuria, hematemesis, hemoptysis) is less likely to be due to a hemostatic abnormality than to a local cause such as neoplasm[emedicine.medscape.com]

  • Wiskott Aldrich Syndrome

    Wiskott-Aldrich syndrome (WAS) is a rare immunodeficiency disease with a characteristic phenotype that includes: X-linked recessive petechiae, bloody diarrhea, epistaxis due[radiopaedia.org] However, affected females have been reported.[patient.info] The clinical presentation of WAS includes several key findings: Bleeding abnormalities - As a result of thrombocytopenia, petechiae, epistaxis, hematemesis and melena are[symptoma.com]

  • Hemophilia B

    Bleeding into muscle, soft tissue or joints (hemarthrosis), GI / GU tract bleeding, easy bruising, excessive bleeding after surgery, trauma, dental procedures or circumcision; epistaxis[pathologyoutlines.com] Thus the vast majority of affected individuals are males although rare females have been reported.[wohproject.org] Tingling, cracking, warmth, pain, stiffness, and refusal to use joint (children) CNS - Headache, stiff neck, vomiting, lethargy, irritability, and spinal cord syndromes GI - Hematemesis[emedicine.medscape.com]

  • Blue Rubber Bleb Nevus Syndrome

    Patients have nonspecific complaints like asthenia caused by chronic hemorrhage due to acute blood loss following hematemesis, rectal bleeding or melena, hemoptysis, hematuria, epistaxis[symptoma.com] Affected Populations Blue Rubber Bleb Nevus Syndrome affects males and females in equal numbers. Approximately 150 cases have been reported in the medical literature.[rarediseases.org] […] pericardium, lungs, peritoneal cavity, adrenal glands, and kidneys 3. hereditary hemorrhagic telangiectasia multiple telangiectasias, pulmonary arteriovenous malformations epistaxis[radiopaedia.org]

  • Gastritis

    Often the result of strain, including sneezing, coughing, vomiting or other kind of strain Nose Epistaxis - nosebleed Mouth Tooth eruption – losing a tooth Hematemesis – vomiting[en.wikipedia.org] […] both sexes with approximately the same frequency, though some studies have noted a slight male predominance. [82] The female-to-male ratio for autoimmune gastritis has been[emedicine.com] […] proton pump inhibitor use iatrogenic: forceful procedures including upper GI endoscopy and nasogastric tube insertion 2 Upper central abdominal pain (maybe severe), nausea, hematemesis[radiopaedia.org]

  • Acquired Hemophilia A

    Persistent wound bleeding and epistaxis suddenly began 6 hours after surgery.[ncbi.nlm.nih.gov] Pediatric cases are rare but have been reported; they may be related to the transplacental crossing of maternal autoantibodies.[symptoma.com] A 71-year-old man presented to the emergency department with his first episode of hematemesis.[ncbi.nlm.nih.gov]

  • Microangiopathy

    Creatinine levels deteriorated, falling to 3.92 mg/dl (0.73 mg/dl on admission), hematocrit fell to 22.6% and thrombocytopenia to 18 000/μl, causing repeated epistaxis.[archbronconeumol.org] Approximately 12 affected males with the fully expressed disorder have been reported. The disorder was first described by Lenz in 1955.[rarediseases.org] Vero cells in culture) Main cause of childhood acute renal failure Usually infants and young children, may occur at any age Symptoms : sudden onset of influenza, bleeding (hematemesis[pathologyoutlines.com]

  • Leiomyosarcoma

    Case Report A 23-year-old man presented with nasal obstruction for 2 months with occasional epistaxis.[ajnr.org] These tumors most commonly affect the uterus and the abdominal cavity. [2] It occurs in the fifth to seventh decade and affects more males than females. [3] Leiomyosarcoma[faoj.org] The tumors may cause bleeding in the gastrointestinal tract and cause black, tarry, foul-smelling stools (melena), or vomiting of blood (hematemesis) or abdominal discomforts[rarediseases.org]

  • Glanzmann Thrombasthenia

    We present a unique case report of a 4-year-old child with known Glanzmann thrombasthenia and two separate episodes of life-threatening epistaxis that were treated successfully[ncbi.nlm.nih.gov] Approximately 500 cases have been reported, but many cases have probably not been reported.[rarediseases.org] Unfortunately, she developed profuse bleeding at the site of G-tube insertion, followed by massive hematemesis.[learningcenter.ehaweb.org]

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