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308 Possible Causes for Affected Females Have Been Reported, Fatigue, Hepatomegaly

  • Primary Sclerosing Cholangitis

    Liver disease other than PSC was defined as autoimmune hepatitis, hepatitis, hepatomegaly, liver failure, cirrhosis, portal hypertension, cholangiocarcinoma, or hepatobiliary[] Primary sclerosing cholangitis (PSC) is a chronic inflammatory disease of bile ducts..Patients with PSC usually presents with fatigue, jaundice and pruritus.[] We report the case of a 51-year-old female affected with psoriatic arthritis concomitant to overlapping primary biliary cholangitis and primary sclerosing cholangitis in whom[]

  • Systemic Lupus Erythematosus

    Other signs are: Pancreatitis, Lupus Enteropathy, Hepatitis and Hepatomegaly 5. Systemic Fever, Malaise/Fatigue, Lymphadenopathy, Weight loss 6.[] Medication usage did not predict fatigue levels. Pain and depression were both unique positive predictors of fatigue.[] In terms of childhood cutaneous LE, prepubertal female-to-male ratios have been reported to be between 1:1 and 3:1, whereas the ratio in postpubertal children is between 8[]

  • Primary Biliary Cirrhosis

    The multifactorial analysis identified bilirubinemia and hepatomegaly as independent predictive variables.[] This Review article discusses the natural history and the measurement of fatigue in patients with PBC.[] The disease primarily affects women over 40 years of age (female preponderance (9–10 1), although younger patients have been diagnosed, including children [2].[]

  • Nephroblastoma

    VOD is primarily a clinical diagnosis characterized by hepatomegaly or pain in the right upper quadrant, jaundice, ascites, and unexplained weight gain.[] […] a pediatrician during a routine check-up, although it may be accompanied by symptoms such as blood in the urine, anemia (which may be accompanied by unusual bleeding or fatigue[] Because affected females typically manifest only the renal features and have normal genitalia and gonads, they are often diagnosed with isolated nephrotic syndrome.[]

  • Muckle-Wells Syndrome

    […] foot [ more ] 0001769 Conjunctivitis Pink eye 0000509 Cranial nerve paralysis 0006824 Episcleritis Inflammation of the thin layer on top of the white part of eye 0100534 Hepatomegaly[] Those diagnosed as adults described musculoskeletal symptoms (86%), rash (67%), hearing loss (52%), and fatigue (29%).[] It affects males and females equally and the onset seems to be during late childhood, or adulthood.[]

  • Pernicious Anemia

    Some people with Pernicious Anemia may have an abnormally enlarged liver (hepatomegaly) or spleen (splenomegaly).[] Signs and Symptoms of Anemia The most common symptom of all types of anemia is fatigue (tiredness).[] A female preponderance ranging from 1.7 to 2.0:1 has been reported in white subjects[ 3 ].[]

  • Methylmalonic Acidemia

    Two days after her discharge, after having a meal rich in protein, she was brought unconscious with hepatomegaly, severe acidosis, ketonuria, and mild hyperammonemia.[] Patients with methylmalonic acidemia with homocystinuria of all types can present with developmental delay, signs of megaloblastic anemia (pallor, fatigue, and anorexia),[] Approximately 12 affected males with the fully expressed disorder have been reported. The disorder was first described by Lenz in 1955.[]

  • Hyperammonemia Type 3

    A congenital form occurs in two types: Type 1, due to deficiency of the enzyme ornithine carbamoyltransferase, is marked by vomiting, lethargy, coma, and hepatomegaly; symptoms[] […] syndrome, Chinese restaurant syndrome, Christian syndrome, Christ-Siemens-Touraine syndrome, Chromosome breakage syndrome, Chronic exertional compartment syndrome, Chronic fatigue[] Affected Populations De Barsy syndrome affects males and females in equal numbers. Fewer than 50 cases have been reported in the medical literature.[]

  • Alpha-Thalassemia

    Concurrent alpha thalassemia might be a protective trait against significant hepatomegaly in sickle cell anaemia patients more than 60 months of age at Mulago hospital.[] Alpha-thalassemia Alpha-thalassemia inheritance pattern Specialty Hematology Symptoms Jaundice, Fatigue Anie KA, Massaglia P (March 2014).[] Approximately 500 cases have been reported, but many cases have probably not been reported.[]

  • Erythropoietic Protoporphyria

    Patients can also present with splenomegaly and hepatomegaly. Liver biopsy in such patients may reveal features of appreciable hepatocellular injury[ 5, 13, 22 - 24 ].[] We ask about general symptoms (anxious mood, depressed mood, fatigue, pain, and stress) regardless of condition. Last updated: May 13, 2019[] Males and females are affected equally.[]

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