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170 Possible Causes for Affected Females Have Been Reported, Fatigue, Megaloblastic Anemia

  • Gastritis

    (pernicious) anemia, autoimmune disorders, and chronic bile reflux.[ariahealth.org] We ask about general symptoms (anxious mood, depressed mood, fatigue, pain, and stress) regardless of condition. Last updated: January 31, 2019[patientslikeme.com] […] both sexes with approximately the same frequency, though some studies have noted a slight male predominance. [82] The female-to-male ratio for autoimmune gastritis has been[emedicine.com]

  • Pernicious Anemia

    In rare cases, megaloblastic anemia is the result of inherited problems: Thiamine-responsive megaloblastic anemia syndrome (TRMA) is a rare inherited megaloblastic anemia[danafarberbostonchildrens.org] Signs and Symptoms of Anemia The most common symptom of all types of anemia is fatigue (tiredness).[web.archive.org] A female preponderance ranging from 1.7 to 2.0:1 has been reported in white subjects[ 3 ].[doi.org]

  • Hereditary Sideroblastic Anemia

    Howell-Jolly body Absent or atrophic spleen, hyposplenism, hemolytic anemia, megaloblastic anemia, alcoholism May see more than one inclusion per cell in megaloblastic anemia[labce.com] Common features include fatigue, dizziness, a rapid heartbeat, pale skin, and an enlarged liver and spleen (hepatosplenomegaly).[icdlist.com] However, about 10 females have been reported to present with CSA where the Lyon's hypothesis of X-chromosome inactivation or an autosomal recessive inheri- tance is used to[indianpediatrics.net]

  • Methylmalonic Acidemia with Homocystinuria Type cblF

    Individuals suffering from HMMAF present with infantile-onset developmental delays and neurological symptoms, and they often have megaloblastic anemia.[symptoma.com] Patients with methylmalonic acidemia with homocystinuria of all types can present with developmental delay, signs of megaloblastic anemia (pallor, fatigue, and anorexia),[orpha.net] They may also show signs of anemia (not megaloblastic), have potentially life-threatening ketoacidosis and/or hyperammonemia, and developmental delay and intellectual deficit[malacards.org]

  • Methylmalonic Acidemia

    Abstract We studied a six-month-old infant with severe megaloblastic anemia, coma and hyperpigmentation of the extremities.[ncbi.nlm.nih.gov] Patients with methylmalonic acidemia with homocystinuria of all types can present with developmental delay, signs of megaloblastic anemia (pallor, fatigue, and anorexia),[orpha.net] Approximately 12 affected males with the fully expressed disorder have been reported. The disorder was first described by Lenz in 1955.[rarediseases.org]

  • Sjögren Syndrome

    The primary feature of this condition is a blood disorder called megaloblastic anemia.[ghr.nlm.nih.gov] […] with fatigue.[ncbi.nlm.nih.gov] Affected Populations Marinesco-Sjögren syndrome affects males and females in equal numbers. More than 200 cases have been reported in the medical literature.[rarediseases.org]

  • Fibromyalgia

    Vitamin B12 and folic acid deficiencies are associated with megaloblastic anemia as well that may lead to fatigue.[news-medical.net] Capuron L, Welberg L, Heim C, et al: Cognitive dysfunction relates to subjective report of mental fatigue in patients with chronic fatigue syndrome.[dx.doi.org] Estimates of prevalence in specific populations vary greatly, but have been reported to be as high as 9% in female textile workers in Turkey and 10% in metalworkers in Brazil[doi.org]

  • Fanconi Anemia

    Although PC is described in patients with various hematological diseases including iron-deficiency anemia, megaloblastic anemia, acquired aplastic anemia, hemolytic anemia[ncbi.nlm.nih.gov] For those children, the first sign is often fatigue.[ucsfbenioffchildrens.org] Affected Populations Fanconi anemia affects males and females in equal numbers. More than 1,200 cases have been reported in the medical literature.[web.archive.org]

  • Plummer-Vinson Syndrome

    […] due to selective vitamin B₁₂malabsorption with proteinuria D511 이머스룬트(-그래스베크)증후군 Imerslund(-Grasbeck) syndrome D511 거적모구성 유전성 빈혈 Megaloblastic hereditary anemia D512 트랜스코발라민[druginfo.co.kr] METHODS: Five males presented to us with dysphagia and fatigue of various durations, from April to August, 2012.[ncbi.nlm.nih.gov] It is known to affect white female mainly but cases have been reported from other ethnic group in the literature.[ispub.com]

  • Autoimmune Polyendocrine Syndrome

    She was diagnosed as megaloblastic anemia with vitamin B12 level: 34 (126.5-505) pg/ml, hemoglobin:11.6 g/dl, and mean corpuscular volume (MCV):102.3 Fl.[jcor.in] , low blood pressure and fatigue.[dermnetnz.org] Males appear to be affected in the expected Mendelian proportions in family reports, but no affected females have been reported. Obligate carrier females are healthy.[jmg.bmj.com]

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