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617 Possible Causes for Age at Onset of Self-Injurious Behavior: 2 Years, Spasticity - Hyperreflexia

  • Lesch Nyhan Syndrome

    In LNS patients there are three major signs of pyramidal dysfunction: spasticity, hyperreflexia and the extensor plantar reflex (also known as the Babinski reflex: the great[themedicalbiochemistrypage.org] They also develop signs of pyramidal involvement including spasticity, hyperreflexia, and extensor plantar reflexes.[ncbi.nlm.nih.gov] ., spasticity, hyperreflexia, extensor plantar reflexes) become evident. Cognitive impairment and behavioral disturbances emerge between ages two and three years.[ncbi.nlm.nih.gov]

  • Primary Lateral Sclerosis

    […] a slowly progressing degenerative brain disease characterized by weakness, spasticity, hyperreflexia, and a positive Babinski sign.[medical-dictionary.thefreedictionary.com] Patients typically present with gradual lower extremity spasticity, hyperreflexia, weakness, and pain, which may be asymmetric at onset.[visualdx.com] Spasticity with hyperreflexia, exaggerated jaw jerk and extensor plantar responses were eventually seen in all patients.[ncbi.nlm.nih.gov]

    Missing: Age at Onset of Self-Injurious Behavior: 2 Years
  • Autosomal Dominant Spastic Paraplegia Type 10

    ) is a rare type of hereditary spastic paraplegia that can present as either a pure form of spastic paraplegia with lower limb spasticity, hyperreflexia and extensor plantar[orpha.net] […] can present as either a pure form of spastic paraplegia with lower limb spasticity, hyperreflexia and extensor plantar responses, presenting in childhood or adolescence, or[orpha.net] Showing of 38 100% of people have these symptoms Lower limb spasticity 0002061 80%-99% of people have these symptoms Distal lower limb amyotrophy 0008944 Lower limb hyperreflexia[rarediseases.info.nih.gov]

    Missing: Age at Onset of Self-Injurious Behavior: 2 Years
  • Hallervorden-Spatz Syndrome

    Described features include 9,11 : progressive dementia extrapyramidal signs (rigidity, dystonia, choreoathetosis) corticospinal signs (spasticity, hyperreflexia) dysarthria[radiopaedia.org] Spasticity, hyperreflexia, and other signs of corticospinal tract involvement are common and eventually limit ambulation.[ncbi.nlm.nih.gov] Corticospinal tract involvement is common and includes spasticity, hyperreflexia, and extensor toe signs. Seizures are rare.[ncbi.nlm.nih.gov]

    Missing: Age at Onset of Self-Injurious Behavior: 2 Years
  • Autosomal Dominant Spastic Paraplegia Type 17

    Central Nervous System: spasticity hyperreflexia clonus difficulty standing walking on tiptoes more Clinical features from OMIM: 607584 UMLS symptoms related to Spastic Paraplegia[malacards.org] […] usually presents in late adolescence or early adulthood as a pure phenotype of lower limb spasticity with hyperreflexia and extensor plantar responses, as well as mild bladder[orpha.net] […] paraplegia characterized by progressive spastic paraplegia, upper and lower limb muscle atrophy, hyperreflexia, extensor plantar responses, pes cavus and occasionally impaired[malacards.org]

    Missing: Age at Onset of Self-Injurious Behavior: 2 Years
  • Pregnancy

    A total of 31 of the 49 infants (63%) had grossly abnormal results on neurologic examinations; hypertonicity, clonus, hyperreflexia, abnormal movements, spasticity, contractures[nejm.org] , hyperreflexia, contractures, dysphagia, and feeding difficulties.[nejm.org] […] have been described in prior case series. 27,28 We have observed a variety of neurologic findings, including visual and hearing deficits, seizure activity, hypertonicity, spasticity[nejm.org]

    Missing: Age at Onset of Self-Injurious Behavior: 2 Years
  • Autosomal Dominant Spastic Paraplegia Type 6

    […] usually presents in late adolescence or early adulthood as a pure phenotype of lower limb spasticity with hyperreflexia and extensor plantar responses, as well as mild bladder[orpha.net] […] limb spasticity with hyperreflexia and extensor plantar responses, as well as mild bladder disturbances and pes cavus.[rarediseases.info.nih.gov] Homepage Rare diseases Search Search for a rare disease Autosomal dominant spastic paraplegia type 6 Disease definition A rare form of hereditary spastic paraplegia which[orpha.net]

    Missing: Age at Onset of Self-Injurious Behavior: 2 Years
  • Autosomal Dominant Spastic Paraplegia Type 8

    24, Autosomal Recessive Symptoms via clinical synopsis from OMIM: 57 Neurologic Central Nervous System: spasticity hyperreflexia clonus difficulty standing walking on tiptoes[malacards.org] Get Update Overview Spastic paraplegia-8 is an autosomal dominant neurologic disorder characterized by adult onset of progressive lower limb spasticity and hyperreflexia resulting[diseaseinfosearch.org] […] paraplegia 8 is a neurologic disorder characterized by severe lower limb spasticity and weakness.[cags.org.ae]

    Missing: Age at Onset of Self-Injurious Behavior: 2 Years
  • Hyponatremia

    They are primarily central nervous system (CNS) manifestations, such as irritability, restlessness, lethargy, muscular twitching, spasticity and hyperreflexia, all of which[aafp.org]

    Missing: Age at Onset of Self-Injurious Behavior: 2 Years
  • Myelopathy

    Physical examination commonly elicits long tract signs such as spasticity, hyperreflexia, and abnormal reflexes such as Babinski or Hoffman's sign.[neurosurgery.ucla.edu] […] gait," hesitant and jerky) Myelopathic or "upper motor neuron" findings such as spasticity, hyperreflexia, clonus, Babinski, and Hoffman signs, and bowel and bladder dysfunction[emoryhealthcare.org] […] and hyperreflexia below the level of the injury level.[amboss.com]

    Missing: Age at Onset of Self-Injurious Behavior: 2 Years

Further symptoms