Agitation & Fatigue & Parkinson's Disease: Causes & Reasons

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Patient File

Sex unknown, Age unknown

Reported Symptoms

Agitation, Fatigue, Parkinson's Disease,

Negated

None

Unsure

None

Possible Causes

Alzheimer Disease

The pain or discomfort caused by pneumonia or a urinary tract infection can result in agitation. [web.archive.org]

Its application is costly in terms of the time employed, with all the negative consequences this entails (decrease in motivation, frustration, and fatigue). [ncbi.nlm.nih.gov]

Parkinson's Disease Rating Scale; MMSE: Mini-Mental State Examination; PD: Parkinson disease; PDD: Parkinson disease dementia. [ncbi.nlm.nih.gov]

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Restless Legs Syndrome

Greater awareness of potential causes of RLS, and its differentiation from akathisia and illness related agitation might help in reducing the distress associated with it and [doi.org]

Is RLS Contributing to Your Fatigue? [verywellhealth.com]

Study Objectives: The association between restless legs syndrome (RLS) and Parkinson's disease (PD) has been extensively studied with inconclusive results; therefore, we prospectively [ncbi.nlm.nih.gov]

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Hypotension

BACKGROUND: Expert consensus panels have recommended risperidone as first-line treatment for agitation of psychiatric origin. [ncbi.nlm.nih.gov]

[…] the Visual Analogue Scale (VAS), and recovery time from fatigue after dialysis at the 0th and 4th week. [ncbi.nlm.nih.gov]

BACKGROUND: Domperidone is a proposed treatment of orthostatic hypotension (OH) in Parkinson's disease (PD). [ncbi.nlm.nih.gov]

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Dementia

Agitation and psychosis are common among older adults with dementia and are challenging to manage. [ncbi.nlm.nih.gov]

Difficulty in concentrating, fatigue, and sleep disturbance do not. 17 No studies to date have examined anxiety disorders other than GAD in this population. [web.archive.org]

To determine which clinical features best characterize Parkinson disease dementia (PDD), compared with Alzheimer disease (AD) and dementia with Lewy bodies (DLB), and to determine [ncbi.nlm.nih.gov]

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Carbon Monoxide Poisoning

The most indicative symptoms experienced were a severe headache, blurred vision, agitation, and confusion. [ncbi.nlm.nih.gov]

Symptoms include headache, fatigue, dizziness, nausea or vomiting, and loss of consciousness. [web.archive.org]

In some severe cases, movement can be effected in a manner similar to Parkinson’s disease. [npower.com]

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Aspiration Pneumonia

Increased impulsiveness or agitation 7. Use of medications such as psychotropic, neuroleptic, antidepressants, anticholinergic, or phenothiazine drugs 8. [patientsafetyinstitute.ca]

We ask about general symptoms (anxious mood, depressed mood, fatigue, pain, and stress) regardless of condition. Last updated: January 31, 2019 [patientslikeme.com]

BACKGROUND: Aspiration pneumonia is an important cause of morbidity and mortality in Parkinson's disease (PD). [ncbi.nlm.nih.gov]

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Carbon Disulfide Poisoning

Certain tank conditions, such as increased liquid volume, agitation and high temperatures, can intensify this already hazardous situation by changing the ratio of H2S in the [asphaltmagazine.com]

This syndrome consists of extreme fatigue, hyperirritability, insomnia, pathological shyness, and depression." [noamalgam.com]

Toluene has been shown to cause Parkinson's Disease or has been associated with people with Parkinson's Disease. [viartis.net]

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Depression

The symptoms of a depressive episode include: Loss of interest or loss of pleasure in all activities Change in appetite or weight Sleep disturbances Feeling agitated or feeling [nami.org]

And while depression doesn’t cause chronic fatigue syndrome, it can certainly cause increased fatigue. [healthline.com]

’s disease and chronic pain, by rewiring a network of signals in the brain. [foxnews.com]

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Encephalitis Lethargica

We describe 2 recent cases of EL characterized by an acute encephalitis with mixed movement disorders (dystonia-Parkinsonism plus stereotypy) and psychiatric disorders (agitated [ncbi.nlm.nih.gov]

Descriptions of lethargy are explored as a way of elucidating concepts of sleep, fatigue, and motivation during the study period. [ncbi.nlm.nih.gov]

Parkinson's Disease is a neurological disorder caused by the lack of dopamine in the brain. [awakenings-brain-bloodbrainbarrier.weebly.com]

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Menopause

Her mood is altered and she may be more agitated, depressed, apathetic, and forgetful. [bodylogicmd.com]

[…] pilot who presented to the Aviation Psychiatry Department with a several-month history of inconsistent training performance, mood lability, tearfulness, anxiety, insomnia, fatigue [ncbi.nlm.nih.gov]

We describe a female patient with stable Parkinson's disease who has shown a marked worsening of her motor functions following therapy of menopause related symptoms with veralipride [ncbi.nlm.nih.gov]

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Pick Disease of The Brain

Aggressive, agitated, or dangerous behaviors could require medication. Anti-depressants and tranquilizers have been shown to improve some symptoms. [secure.ssa.gov]

For example, they may check and treat you for: depression and other mood disorders anemia, which can cause fatigue, headaches, moodiness, and difficulty concentrating nutritional [healthline.com]

It is also known as Pick disease and PiD (not to be confused with pelvic inflammatory disease (PID) or Parkinson's disease (PD)). [en.wikipedia.org]

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Parasomnia

Thirty-four participants (mean [ /-SD] age 22.7 [ /-12.9] years) noting nocturnal motor agitation or behaviors and 12 healthy controls (mean age 24.1 [ /-3.1] years) underwent [ncbi.nlm.nih.gov]

Anxiety and fatigue are also associated with the disorder. [news-medical.net]

OBJECTIVE: To characterize parasomnia behaviors on arousal from NREM sleep in Parkinson's Disease (PD) and Multiple System Atrophy (MSA). [ncbi.nlm.nih.gov]

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Syncope

Another key differentiating feature is the lack of prolonged postictal obtundation or agitation after a faint. [reliasmedia.com]

[…] small percentage of patients taking the drug Recent Examples on the Web According to the Harford County Health Department, heat illness takes many forms, including heat fatigue [merriam-webster.com]

Syncope isn’t normally a primary sign of a neurological disorder, but it may indicate an increased risk for neurologic disorders such as Parkinson’s disease, postural orthostatic [ninds.nih.gov]

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Substance Abuse Problems

Milder symptoms such as agitation, restlessness, and insomnia are more common. [emedicine.medscape.com]

These symptoms can include : Loss of interest and pleasure Irritability and anger Changes in appetite Sleep problems Fatigue Slow movement and thinking Feelings of worthlessness [centerforanxietydisorders.com]

Dopamine agonists and risk: impulsive control disorders in Parkinson’s disease. [ncbi.nlm.nih.gov]

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Hyponatremia

On admission, the patient was agitated and had slurred speech. Treatment with hypertonic saline lead to full recovery. [ncbi.nlm.nih.gov]

Our patient complained of left knee pain, fatigue, and bilateral lower limb cramps. [ncbi.nlm.nih.gov]

Dementia has many risk factors[ 22 ], including age, sex, DM, hypertension, hyperlipidemia, atrial fibrillation, coronary artery diseases, mental illness, and Parkinson’s [journals.plos.org]

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Anxiety Disorder

[…] history of panic disorder and one patient with a history of generalized anxiety disorder were treated with buspirone and experienced an increase in their anxiety levels, agitation [ncbi.nlm.nih.gov]

[…] characterized by at least 6 months of pervasive and excessive anxiety; recurring worry about common events; and physical symptoms, such as muscle tension, insomnia, and fatigue [doi.org]

[…] in Parkinson's Disease, 10.1016/bs.irn.2018.08.002, (173-210), (2018). [doi.org]

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Chronic Alcoholism

Agitation. If you feel restless, agitated or discontent without alcohol in your bloodstream, you should start to reevaluate your drinking habits. Comments from others. [michaelshouse.com]

Chronic alcoholism can affect the circulatory system, increase the risk of anemia and lead to complaints like fatigue, breathlessness and lightheadedness. [epainassist.com]

There was a progressive development of parkinsonism, cerebellar ataxia, and mental deterioration by the time he was 32. [ncbi.nlm.nih.gov]

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Alcohol Withdrawal

A significant number of patients with terminal cancer experience terminal restlessness or an agitated delirium in the final days of life. [ncbi.nlm.nih.gov]

Individuals however, tend to suffer from insomnia, fatigue and irritability for several months. [symptoma.com]

As a depressant, alcohol can trigger episodes of depression, anxiety and lethargy, brain damage (Korsakoff's syndrome), and Parkinson's disease. [uncommonhelp.me]

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Orthostatic Hypotension

An amphetamine -- side effects may include agitation, tremor, insomnia, supine hypertension. Ephedrine 12.5-25 mg orally three times/day. [dizziness-and-balance.com]

The patient is a 76 year-old woman who presented with progressive dizziness, anorexia, and fatigue. [ncbi.nlm.nih.gov]

KEYWORDS: Cognition; Executive functions; Orthostatic hypotension; Parkinson’s disease [ncbi.nlm.nih.gov]

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Congestive Heart Failure

Patients with severe LV failure may appear visibly dyspneic or cyanotic, hypotensive, and confused or agitated because of hypoxia and poor cerebral perfusion. [msdmanuals.com]

Fatigue and exertion fatigue. From description through validation to application of the Dutch Fatigue Scale (DUFS) and the Dutch exertion scale (DEFS). [dx.doi.org]

Valvular heart disease and the use of dopamine agonists for Parkinson’s disease. N Engl J Med. 2007 ; 356 :39–46. doi: 10.1056/NEJMoa054830. [doi.org]

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Hyperpyrexia

At the end of surgery, following extubation he developed agitation, intense shivering and hyperpyrexia, and his level of consciousness decreased to a Glasgow Coma score of [ncbi.nlm.nih.gov]

The main clinical symptoms are fever, septicemia, headache, fatigue and myalgia. The disease usually begins with a high fever. [scopemed.org]

Motor Disease Early in the disease course, patients with Parkinson’s disease have a smooth and predictable response to dopaminergic medications. [emdocs.net]

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Pulmonary Edema

Neurogenic pulmonary edema is suggested by her acute agitation. [professional.diabetes.org]

You may experience: shortness of breath, chest discomfort, heart palpitations, coughing, difficulty walking uphill, fatigue, fever, or headaches. [lungmds.com]

CBD Oil and Parkinson’s Disease Exercises that Ease Arthritis Proving Painsomnia is Real: A Case Study Acute Flaccid Myelitis Causes and Diagnosis Antibodies and Huntington's [news-medical.net]

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Severe Depressive Episode

[…] lack of energy Changes in appetite (usually weight loss as a result of reduced appetite but increased cravings for food and weight gain is seen in some people) Anxiety, agitation [symptoma.com]

A depression was understood as an unnatural fatigue resulting from an uneconomic hyperarousal of the vegetative nervous system and the dysfunction of the metabolic system [books.google.com]

(National Institute of Mental Health, 2002) Parkinson's Disease: 50% of Parkinson's disease patients may experience depression. [dbsalliance.org]

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Hyperthyroidism

After tracheal extubation, the patient exhibited abnormal tachycardia, agitation, sweating, and hyperpyrexia. [ncbi.nlm.nih.gov]

It is the largest study to date of this population and will help mental health ... read more Chronic Fatigue Syndrome Possibly Explained by Lower Levels of Key Thyroid Hormones [sciencedaily.com]

» Coronavirus Resource Center » The facts about Parkinson’s Disease » What’s causing bladder pain or burning? [health.harvard.edu]

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Migraine

Another typical feature is that most cluster headache patients are restless or agitated during attacks. [web.archive.org]

Adverse events included paresthesia, fatigue, nausea, and anorexia. [aafp.org]

Author information 1 Parkinson's Disease Center and Movement Disorders Clinic, Department of Neurology, Baylor College of Medicine, Houston, TX, USA. 2 Department of Neurology [ncbi.nlm.nih.gov]

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Petroleum Distillates Poisoning

Arrhythmias usually occur before presentation and are unlikely to recur after presentation unless patients have excessive agitation. [msdmanuals.com]

[…] metabolized by the liver with a biological half-life of 46–48 h. [3] Inhalation overexposure causes primarily central nervous system (CNS) effects (headaches, dizzines, nausea, fatigue [en.wikipedia.org]

Will you have Petroleum distillate poisoning with Parkinson's disease - from FDA reports Summary There is no Petroleum Distillate Poisoning reported by people with Parkinson's [ehealthme.com]

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Parkinson's Disease Type 3

[…] apathy, anxiety disorders (including panic disorders, generalized anxiety disorder, and social phobia), depression, psychosis (hallucinations), behavioral disturbances (agitation [orpha.net]

Fatigue. Many people with Parkinson's disease lose energy and experience fatigue, especially later in the day. The cause isn't always known. Pain. [mayoclinic.org]

Parkinson's disease type 3 (PD3) is a form of Parkinson's disease that is inherited in an autosomal dominant manner. [symptoma.com]

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Hereditary Late-Onset Parkinson Disease

LOPD patients report a lower prevalence of non-motor symptoms such as depression, hallucinations, behavioral disturbances (i.e. agitation or impulse control disorder), dementia [orpha.net]

Fatigue. Many people with Parkinson's disease lose energy and experience fatigue, especially later in the day. The cause isn't always known. Pain. [mayoclinic.org]

Parkinson Disease. [malacards.org]

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Bipolar Disorder

He was psychiatrically hospitalized for agitation, aggression, and manic symptoms including insomnia, rapid and pressured speech, and hyperactivity. [ncbi.nlm.nih.gov]

Possible benzodiazepine side effects include: Drowsiness or dizziness Lightheadedness Fatigue Blurred vision Slurred speech Memory loss Muscle weakness Benzodiazepines can [webmd.com]

In Parkinson's disease, administration of high-dose dopamine precursors can produce a 'maniform' picture, which switches into a depressive analogue on withdrawal. [ncbi.nlm.nih.gov]

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Heart Failure

Fatigue and exertion fatigue. From description through validation to application of the Dutch Fatigue Scale (DUFS) and the Dutch exertion scale (DEFS). [dx.doi.org]

Valvular heart disease and the use of dopamine agonists for Parkinson’s disease. N Engl J Med. 2007 ; 356 :39–46. doi: 10.1056/NEJMoa054830. [doi.org]

[…] of cardiac functional impairment secondary to many aetiologies, and patients with HF experience a range of symptoms that affect their quality of life, including dyspnoea, fatigue [radcliffecardiology.com]

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