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140 Possible Causes for Akathisia, Melatonin

  • Insomnia

    The ability of melatonin to shift biological rhythms is well known.[doi.org] Serious adverse events identified from case reports included fatal hepatotoxicity, restless legs syndrome, akathisia, and weight gain.[ncbi.nlm.nih.gov] Acute akathisia associated with quetiapine use. Psychosomatics 2005 ; 46: 291 – 301. DOI 10.1176/appi.psy.46.4291 Google Scholar Crossref Medline ISI 24.[doi.org]

  • Dementia

    There were three parallel groups receiving either melatonin 10 mg, melatonin SR 2.5 mg, or placebo for eight weeks.[doi.org] Nurse managers checked lists of psychomotor adverse effects, including 13 items describing pseudoparkinsonism, akathisia, acute dystonic reaction and tardive dyskinesia.[doi.org] No serious adverse effects of melatonin were reported in the included studies.[ncbi.nlm.nih.gov]

  • Orofacial Dyskinesia

    Melatonin.[globalrph.com] The term "tardive dyskinesia" was first introduced in 1964 and is now commonly used to identify any tardive movement disorder, including stereotypy, akathisia, dystonia, myoclonus[medlink.com] Akathisia Akathisia refers to complex movements such as tics, compulsions, and mannerisms that are stereotypic and usually relieved when executing a motor act.[encyclopedia.com]

  • Delirium

    This search yielded a total of 2 RCTs for melatonin.[doi.org] Potential side effects include extra-pyramidal symptoms (EPS), including parkinsonism, akathisia, and dystonia, and prolongation of the QTc interval, particularly with use[bcmj.org] The objective of this review is to summarize the available data on the use of melatonin and melatonin agonist for the prevention and management of delirium in the elderly[ncbi.nlm.nih.gov]

  • Restless Legs Syndrome

    As it gets darker, the hormone norepinephrine triggers release of the “sleep hormone” melatonin to ready you for sleep.[womentowomen.com] […] basis of RLS and akathisia.[ncbi.nlm.nih.gov] Melatonin concentrations in older patients peak later at night at about half the plasma levels of younger people. 24 The relative melatonin deficiency that accompanies aging[doi.org]

  • Sleep Disturbance

    Melatonin had no effect on sleep onset latency (melatonin 1.37 vs. placebo 1.42, log units; difference -0.05; 95% CI, -0.14 to 0.03; p   0.23).[ncbi.nlm.nih.gov] Dystonia 333.82 Neuroleptic-Induced Tardive Dyskinesia 333.90 Medication-Induced Movement Disorder NOS 333.92 Neuroleptic Malignant Syndrome 333.99 Neuroleptic-Induced Acute Akathisia[northsoundbho.org] KEYWORDS: concussion; melatonin; mild traumatic brain injury; pediatric; sleep disturbance; treatment[ncbi.nlm.nih.gov]

  • Tardive Dyskinesia

    ) Treatment name GINKGO Effectiveness: Possibly Effective Read Reviews (72) Treatment name LECITHIN Effectiveness: Insufficient Evidence Read Reviews (55) Treatment name MELATONIN[webmd.com] Three common TD variants, which may be acute or tardive (occurring after long-term antipsychotic therapy), are: akathisia, a distressing and at times irresistible urge to[mdedge.com] “There have been several other medicines touted including ginkgo biloba, melatonin, and Yi-gan san – none of those have any controlled data supporting them,” Ondo said.[mdmag.com]

  • Pineal Gland Dysfunction

    Stress and dietary habits may lead to deficiencies of both serotonin and melatonin. Melatonin inhibits the release of cortisol via the release of vasotocin.[ncbi.nlm.nih.gov] The drug induced (iatrogenic) conditions Akathisia & Mania are well documented in the medical litarature.[antidepressantsfacts.com] The production of melatonin by the pineal gland is stimulated by darkness and inhibited by light.[liquidprofessionalhcg.com]

  • Benzodiazepine Withdrawal

    INTERVENTION: Melatonin (5 mg/day) or placebo: 6 weeks one arm, 1 week washout, 6 weeks other arm.[ncbi.nlm.nih.gov] The use of typical neuroleptics may lead to side effects, such as akathisia, which may in turn precipitate additional agitation.[ncbi.nlm.nih.gov] Antidepressants (and other psychotropic drugs) carry similar risks for physical dependence and adverse effects, which may be permanent to include Tardive Dyskinesia, akathisia[w-bad.org]

  • Psychomotor Retardation

    Melatonin may help disabled children suffering from sleep disorders.[ncbi.nlm.nih.gov] Quantitative assessment of psychomotor activity in patients with neuroleptic-induced akathisia. Prog. Neuropsychopharmacol. Biol. Psychol. 16: 27-37.[link.springer.com] , droperidol or other usual antipsychotics can lessen the length of agitation triggered by severe psychosis, but must be evaded if psychomotor agitation is assumed to be akathisia[epainassist.com]

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