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1,578 Possible Causes for Akinesia, 'Eye of the Tiger' Sign on MRI, Mask-like Facies

  • Juvenile Paralysis Agitans of Hunt

    Associated, reflex, and voluntary movements are absent (akinesia). Muscle tone is plastic, and the extremity can move only passively.[encyclopedia2.thefreedictionary.com] Parkinsonismo precoce associado a lesões palidais de tipo "eye-of-the-tiger" "Eye-of-the-tiger" sign at MRI in a patient with early-onset parkinsonism Egberto Reis Barbosa[scielo.br] Resting and action tremor, akinesia, stooped posture, distortion of the trunk, dystonia of the upper extremities, oculogyric crisis, and impairment of the postural reflex[ncbi.nlm.nih.gov]

  • Parkinson's Disease

    Acute akinesia (AA) is an unusual motor complication in Parkinson's disease (PD).[ncbi.nlm.nih.gov] Facial expression is blunted, described as a "masked facies". The patient typically has difficulty with the initiation of movement.[clinicaladvisor.com] Abstract We herein report the case of a 43-year-old man with a 4-year history of resting tremor and akinesia.[ncbi.nlm.nih.gov]

    Missing: 'Eye of the Tiger' Sign on MRI
  • Parkinson's Disease Type 3

    Moreover clinical features are variable with some patients presenting with akinesia and rigidity only and others with a tremor dominant type.[pmj.bmj.com] Other characteristic symptoms of Parkinson disease include rigidity or stiffness of the limbs and torso, slow movement (bradykinesia) or an inability to move (akinesia), and[ghr.nlm.nih.gov] […] disease is a common neurodegenerative condition, with an estimated prevalence of approximately 1 in 100 persons. 1 Parkinson's disease is characterized by resting tremor, akinesia[nejm.org]

    Missing: 'Eye of the Tiger' Sign on MRI
  • X-linked Parkinsonism-Spasticity Syndrome

    Supportive features:  symmetrical akinesia or rigidity  proximal more than distal  abnormal neck posture  especially retrocollis  poor or absent response of parkinsonism[slideshare.net] T2-weighted fast spin echo (G) and T1-weighted (H) brain MRI scans from a child with PKAN demonstrating the "eye of the tiger" sign (courtesy of Susan J.[ojrd.biomedcentral.com] T2 weighted brain MRI shows an ”eye of the tigersign corresponding to pallidal hypointensity with a high signal center.[neuroweb.us]

  • Parkinson-Dementia Syndrome

    During the disease course, akinesia and rigidity were present in all cases and classic resting tremor was noted in 29 (table 1).[jnnp.bmj.com] Vingerhoets et al.16 claimed that patients with initial tremor are more likely to suffer cognitive impairment in the more advanced stages of PD compared with patients with akinesia[demneuropsy.com.br] […] tremor), Hoehn and Yahr stage, response to dopaminergic treatment (% of improvement in motor disability), complications of treatament (such as early morning and nocturnal akinesia[jnnp.bmj.com]

    Missing: 'Eye of the Tiger' Sign on MRI
  • Progressive Supranuclear Palsy

    METHODS: We retrospectively enrolled 48 patients with PSP composed of 25 patients with PSP-Richardson's syndrome (RS) and 23 patients with pure akinesia with gait freezing[ncbi.nlm.nih.gov] PSP-Pure akinesia with gait freezing (PSP-PAGF) is characterized by progressive freezing of gait, speech and writing early in the course of the disease.[orpha.net] […] a patient with amnestic dementia developing frontal lobe dementia, Parkinsonism and supranuclear gaze palsy and a patient with cerebellar ataxia and nystagmus developing akinesia[ncbi.nlm.nih.gov]

    Missing: 'Eye of the Tiger' Sign on MRI
  • Postencephalitic Parkinson Disease

    In uncontrolled studies, two-thirds of patients who received amantadine monotherapy experienced improvements in akinesia, rigidity, and tremor.[enotes.tripod.com] PARKINSON’S DISEASE Parkinson’s disease is characterized by a characteristic pill rolling tremor, bradykinesia, mask-like facies with a reduced blinking frequency (hypomimia[thebigl.co] See also: dopamine agonist Akinesia Inability to move ("freezing") or difficulty in initiating or maintaining a body motion.[michaeljfox.org]

    Missing: 'Eye of the Tiger' Sign on MRI
  • Hallervorden-Spatz Syndrome

    Two siblings were seen in our outpatient movement disorders clinic with an indolent clinical picture of a pure akinesia syndrome.[ncbi.nlm.nih.gov] Iron deposition in conjunction with destruction of the globus pallidus gives rise to the characteristic eye-of-the-tiger sign in MRI.[ncbi.nlm.nih.gov] At the age of 22, she suffered from akinesia, resting tremor, and rigidity.[ncbi.nlm.nih.gov]

    Missing: Mask-like Facies
  • Malignant Hyperthermia - Arthrogryposis - Torticollis

    Microphthalmia camptodactyly mental retardation Microphthalmia cataract Microphthalmia diaphragmatic hernia Fallot Microphthalmia mental deficiency Microphthalmia microtia fetal akinesia[en.wikipedia.org] facies Expressionless face Lack of facial expression Mask-like facial appearance [ more ] 0000298 Metatarsus adductus Front half of foot turns inward 0001840 Plagiocephaly[rarediseases.info.nih.gov] Microphthalmia microtia fetal akinesia[?] Microphthalmia, Lentz type[?] Microphthalmia[?] Microphthalmos, microcornea, and sclerocornea[?] Microscopic polyangiitis[?][encyclopedia.kids.net.au]

    Missing: 'Eye of the Tiger' Sign on MRI
  • Wilson Disease

    She underwent successful transplant from a hepatic and surgical standpoint, but her postoperative course was marked by protracted mutism, hypophonia, and fluctuating akinesia[ncbi.nlm.nih.gov] Some have a mask-like facies and pseudobulbar symptoms. Symptoms can appear anytime from 3 years of age to over 50.[disorders.eyes.arizona.edu] Neurologic disease may present in various forms - tremor, akinesia, ataxia, dystonia with severe contractures and rigidity similar to Parkinson's disease, whereas spasticity[symptoma.com]

    Missing: 'Eye of the Tiger' Sign on MRI

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