Create issue ticket

19 Possible Causes for Akinetic Mutism, Prominent Sulci

  • Cerebral Cortical Atrophy

    Imaging wise feature of cerebral cortical atrophy Generalized prominence of hemisphere cortical sulci on CT or MRI in mild cases.[neuroradiologycases.com] Characteristic features include prominent cerebral sulci (i.e. cortical atrophy) and v entriculomegaly (i.e. central atrophy) without bulging of the third ventricular recesses[radiopaedia.org] Characteristic features include prominent cerebral sulci (i.e. cortical atrophy) and ventriculomegaly (i.e. central atrophy) without bulging of the third ventricular recesses[homeoguru.com]

  • Brain Stem Disorder

    As arousal improves, behavioural disturbances become evident, such as hemineglect, amnestic syndromes (5, 7), akinetic mutism, or subcortical demented states with apathy and[neuroophthalmology.ca] There is a prominent ventral cleft at the level of the pontomedullary junction.[ajnr.org] Behavioral disturbances from thalamic damage include hemineglect, amnestic syndromes (5, 7), akinetic mutism, or subcortical demented states with apathy and slowness of thought[neuroophthalmology.ca]

  • Creutzfeldt Jakob Disease

    mutism.[ncbi.nlm.nih.gov] B, Corresponding FLAIR image shows marked prominence of ventricles and sulci for the patient’s age.[ajnr.org] Four months after the onset, she entered a state of an akinetic mutism. Gene analysis revealed a homozygous V203I mutation in the PRNP.[ncbi.nlm.nih.gov]

  • Hypoxia

    But his neurological condition deteriorated later on and gradually progressed into akinetic mutism and generalized hypertonia within 3 weeks.[ncbi.nlm.nih.gov] Grossly, the lesion was marked by preserved gyral crests and involved sulci, resulting in prominent, mushroom-shaped gyri.[emedicine.medscape.com] mutism, and rarely catatonia.[ncbi.nlm.nih.gov]

  • Normal Pressure Hydrocephalus

    Langheim, Syndrome of akinetic mutism associated with obstructive hydrocephalus. Neurology (Minneap.) 16 (1966), 635–649. Google Scholar 9. Daly, D., J. L. Whelan, R. G.[link.springer.com] NPH is suggested when ventricular dilation is out of proportion to the prominence of the sulci, but this is a subjective call.[docneuro.com] mutism).[ncbi.nlm.nih.gov]

  • Dihydropyrimidine Dehydrogenase Deficiency

    Reversible leukoencephalopathy caused by 5-fluorouracil derivatives, presenting as akinetic mutism. Surg Neurol. 1986; 25 : 279 –282.[neurology.org] Head MRI showed prominent sulci and abnormal T2 prolongation in the cerebral white matter and brainstem.[ncbi.nlm.nih.gov] Thus, DPD deficiency may feature prominent brain abnormalities involving the cerebral white matter and brainstem.[ncbi.nlm.nih.gov]

  • Meningoencephalitis

    mutism, central respiratory irregularities, or somnolence and/or sleep inversion. 14 The CSF is frequently abnormal, with signs of meningeal irritation, ie, increased pressure[jamanetwork.com] MRI of the brain showed some effacement of cortical sulci, rendering the vessels prominent, with increased T2-weighted signal diffusely scattered throughout both hemispheres[academic.oup.com] […] encephalitis associated with at least 3 of the following major criteria: signs of basal ganglia involvement, oculogyric crises, ophthalmoplegia, obsessive-compulsive behavior, akinetic[jamanetwork.com]

  • Subacute Sclerosing Panencephalitis

    Stage III Rigidity, extra-pyramidal symptoms, progressive unresponsiveness Stage IV Coma, vegetative state, autonomic instability and akinetic mutism Table 1 Clinical stages[doi.org] They can range from hyperintensities in the parietal and occipital region, brain stem lesions, and marked atrophy, causing prominence of sulci.[cureus.com] Although catatonia is seen in patients with many neurological illnesses as presenting symptom, but akinetic mutism has been seen only in advanced illness in case of SSPE.[ijpm.info]

  • Neuhauser Syndrome

    mutism Aksu von Stockhausen Syndrome Al Awadi Syndrome Al Gazali Aziz Salem Syndrome Al Gazali Hirschsprung Syndrome Al Gazali Khidr Prem Chandran Syndrome Al Gazali Sabrinathan[rgd.mcw.edu] Cranial magnetic resonance imaging (MRI): prominent subarachnoid cortical sulci, Sylvian issure, and basal cisterns. Fig 2.[text-br.123dok.com] Extragenital Malformations AICAR Transformylase Inosine Monophosphate Cyclohydrolase Deficiency Aicardi syndrome Aicardi-Goutieres syndrome Akaba Hayasaka Syndrome Akesson Syndrome akinetic[rgd.mcw.edu]

  • Autosomal Recessive Isolated Optic Atrophy

    Features of stage IV include active startle reflex, flexor limb positioning, quadraparesis, akinetic mutism, wandering eye movements and coma.[neuroweb.us] Also note on coronal T2W (B) image the prominence of cerebellar fissures (arrowhead) and cortical sulci suggestive of atrophy Click here to view The diagnosis is often delayed[ijri.org]

Further symptoms