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166 Possible Causes for Alanine Aminotransferase Increased, Burning Pain, Leg Swelling

  • Erythropoietic Protoporphyria

    Older children complain of burning pain . Repeated exposure to the sun causes skin thickening on the knuckles and scars on the nose, cheeks, and back of the hands.[epainassist.com] One or more of these was increased in 17 (25%) patients; sFn correlated with γ-glutamyl transpeptidase (r s 0.507; P .001) and alanine aminotransferase (r s 0.392; P .001)[doi.org] Older children complain of burning pain. Repeated exposure to the sun causes skin thickening on the knuckles and scars on the nose, cheeks, and back of the hands.[epainassist.com]

  • Liver Cirrhosis

    The rash is often painful and causes a burning sensation.[emedicinehealth.com] aminotransferase (ALT) is found abundantly in the cytosol of hepatocytes, and the liver has approximately 3000 times more ALT than serum.[doi.org] You may also get swelling in your legs, ankles or feet, known as peripheral oedema.[britishlivertrust.org.uk]

  • Polycythemia Vera

    Doctors can also treat the itchy skin and burning pain that you may experience.[familydoctor.org] […] with or without associated elevations in alanine aminotransferase and aspartate aminotransferase have been reported in patients with chronic hepatitis B virus (HBV) infections[jakafi.com] […] pain or swelling in arms or legs shortness of breath ruddy color in the face, hands, and feet chest pain sweating increased cough coughing up blood Cardiopulmonary problem[uihc.org]

  • Gaucher Disease

    ; three patients showed pressure pain hyperalgesia.[ncbi.nlm.nih.gov] Temporary swelling in the legs has also been observed with drugs like Cerezyme. Please see Full Prescribing Information (PDF).[cerezyme.com] At quantitative sensory testing, all of them showed high cold thresholds with errata sensation (burning instead of cold), paradoxical heat sensation and mechanic hypoesthesia[ncbi.nlm.nih.gov]

  • Obesity

    Chronic regional pain syndrome (CRPS) type 2 has been defined as a burning pain allodynia and hyperpathia usually in the hand or foot after partial injury of a nerve or one[doi.org] […] by a factor of at least 2 above the upper limit of normal in alanine aminotransferase and aspartate aminotransferase levels), had gastrointestinal problems that would prevent[doi.org] A 35-year-old man (height, 169 cm; body weight, 240 kg; BMI, 84) visited the Department of Dermatology due to left leg pain and swelling.[ncbi.nlm.nih.gov]

  • Osteoarthritis

    Pain Joints may ache, or the pain may feel burning or sharp. For some people, the pain may come and go.[stemgenex.com] The diclofenac group experienced greater increases in mean alanin and aspartate aminotransferase levels. No episodes of GI bleeding were reported.[doi.org] In addition, patients can develop bone spurs and one leg can appear shorter than the other.[my.clevelandclinic.org]

  • Fibromyalgia

    Fibromyalgia Symptoms The main symptoms of fibromyalgia are: Deep or burning pain in your trunk, neck, low back, hips, and shoulders Tender points (or trigger points) on the[weillcornell.org] aminotransferase increased, alkaline phosphatase increased, anaphylactic reaction, angioneurotic edema, aspartate aminotransferase increased, bilirubin increased, glaucoma[en.wikipedia.org] Possible side effects may include drowsiness, weight gain, swelling in the legs, blurred vision and co‐ordination problems.[doi.org]

  • Diabetes Mellitus

    Signs and symptoms of peripheral neuropathy are often worse at night, and may include: Numbness or reduced ability to feel pain or temperature changes Tingling or burning[mayoclinic.org] Abdominal subcutaneous fat area (SFA), visceral fat area, total fat area assessed by abdominal CT, aspartate aminotransferase, alanine aminotransferase (ALT), and γ-glutamyl[ncbi.nlm.nih.gov] TABLE 1 Signs of Kidney Disease in Patients with Diabetes Albumin/protein in the urine High blood pressure Ankle and leg swelling, leg cramps Going to the bathroom more often[kidney.org]

  • Sleep Apnea

    The management of pain after burn injuries is a clinical challenge magnified in patients with significant comorbidities.[ncbi.nlm.nih.gov] An increase (or decrease) in alanine aminotransferase (ALT) is often used as a biochemical marker to monitor progression (or amelioration) of NAFLD, despite the fact that[doi.org] swelling (if apnea is severe) Your health care provider will take your medical history and do a physical exam.[medlineplus.gov]

  • Constrictive Pericarditis

    The pain is sharp and stabbing, but may also be felt as a dull, ache or burning pain. The intensity may be mild or very severe and it can come on gradually or suddenly.[medicinenet.com] […] alkaline phosphatase (178 U/l) and gamma-glutamyl transpeptidase (109 U/l), normal aspartate aminotransferase, alanine aminotransferase and total bilirubin, reduced total[revportcardiol.org] Abstract A middle-aged male presented with symptoms of exertional shortness of breath and leg swelling for the past six months.[ncbi.nlm.nih.gov]

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