Albumin Decreased: Causes & Reasons

Warning: Do not use in emergencies, if pregnant, if under 18, or as a substitute for a doctor’s advice or diagnosis. Learn more

Possible Causes for Albumin Decreased

Capillary Leak Syndrome

Laboratory data showed an increase in hematocrit (65%), leucocytes (24.590 μ/L), creatinine (2.5 mg/dL), creatine phosphokinase (10.000 U/L), and a decrease in serum albumin [ncbi.nlm.nih.gov]

Patients with a greater decrease in albumin level had a higher likelihood of developing rhabdomyolysis (p=.03). [ncbi.nlm.nih.gov]

The sudden and profound capillary leak causes a sharp decrease in serum albumin level (hypoalbuminemia) and a similarly sharp increase in the level of hemoglobin and hematocrit [rarediseases.org]

Protein-Losing Enteropathy

After the heart transplantation, the albumin level decreased to 2.3 g/dl, and therefore it was restarted. [ncbi.nlm.nih.gov]

However, the correlation between the decrease in serum albumin and liver function is far from linear and arguments in favor of an additive role of protein-losing enteropathy [ncbi.nlm.nih.gov]

After 8 weeksBCAA supplementation, the ratio of oxidized albumin within total albumin decreased significantly and that of reduced albumin increased significantly (P < 0.05 [forum.bodybuilding.com]

Nephrotic Syndrome

See also nephrosis. neph·rot·ic syn·drome a clinical state characterized by edema, albuminuria, decreased plasma albumin, doubly refractile bodies in the urine, and usually [medical-dictionary.thefreedictionary.com]

Taking a diuretic medication to decrease fluid in the body Taking a blood pressure medication to help lower blood pressure Taking an albumin infusion to decrease swelling [multicare.org]

Synonym(s): nephrotic syndrome neph·rot·ic syn·drome ( nef-rot'ik sin'drōm ) Clinical state characterized by edema, albuminuria, decreased plasma albumin, doubly refractile [medical-dictionary.thefreedictionary.com]

Analbuminemia

The disease is caused by mutations in the human serum albumin (HSA) gene which result in a markedly decreased serum albumin concentration (estimated at between 1/100th to [renalfellow.blogspot.com]

Long-term atorvastatin therapy together with periodic albumin infusions may contribute to decreasing cardiovascular risk safely in this clinical setting. [wjgnet.com]

It also hints that perhaps something other than the hypoalbuminemia and subsequent loss of oncotic pressure observed in patients with nephrotic syndrome is responsible for [renalfellow.blogspot.com]

Kwashiorkor

Hypovolemic shock: The incompetent fatty liver in Kwashiorkor will decrease the albumin production and decrease the osmotic gradient in the intracellular spaces. [symptoma.com]

[…] haematocrit, blood volume, decreased albumin Treatment Succotash, a diet mixture that provides the deficient amino acids kwa·shi·or·kor ( kwah-shē-ōr'kōr ) A disease seen [medical-dictionary.thefreedictionary.com]

Total protein albumin and globulin determination to assess the levels of hypoalbuminemia and hypoglobulinemia. [symptoma.com]

Cardiac Cirrhosis

albumin and globulin, prothrombin time prolonged, the latter can not be corrected with vitamin K, and with the improvement of congestive heart failure and gradually Back [healthfrom.com]

[…] in CHF The congested liver is usually enlarged and firm, often associated with slight enlargement of the spleen Modest elevations of ALT, AST, LDH, r-GT,ALP, T-Bil small decreases [powershow.com]

Serum albumin levels can be decreased in a 40% of patients. [ncbi.nlm.nih.gov]

Hypertrophic Gastritis

(low blood serum level of albumin) Excess mucus secretion in the stomach Decreased acid secretion by the stomach The low level of acid secretion results in a failure to digest [dovemed.com]

[…] serum level of albumin) due to loss of albumin by the stomach. [medicinenet.com]

A high-protein diet should be recommended to replace protein loss in patients with low levels of albumin in the blood (hypoalbuminemia). [en.wikipedia.org]

Cronkhite-Canada Syndrome

Total protein was within normal range, but the serum albumin level was moderately decreased [3.1g/dl, normal range 4.0–5.0g/dl]. [academic.oup.com]

Serum protein electrophoresis revealed a decrease in the albumin fraction in 50% of patients and elevation of α 1, globulin in 59.1%. [kjim.org]

Serum protein electrophoresis revealed a decrease in the albumin fraction in 50% of patients and elevation of α1, globulin in 59.1%. [kjim.org]

Macronodular Cirrhosis

decreased in chronic liver diseases. prothrombin time: increased in acute and chronic liver diseases. [quizlet.com]

Data from liver function tests usually show elevated transaminase levels, elevated bilirubin levels, and decreased values for albumin and clotting factors. [medical-dictionary.thefreedictionary.com]

Protein metabolism tests show decreased total protein, decreased albumin, and increased globulin. [medical-dictionary.thefreedictionary.com]

Portal Cirrhosis

[…] platelets Splenomegaly Reduced hepatic production of thrombopoietin Direct toxic effect of alcohol on the bone marrow Albumin Decreased in advanced cirrhosis Decreased hepatic [pathophys.org]

Albumin will decrease and this is a marker for reduced synthetic function of the liver. [kenhub.com]

Their big concerns are encephalopathy (toxins), bleeding problems (loss of clotting factors and platelets), ascites (decreased albumin), chronic jaundice (build up of bilirubin [tissupath.com.au]

Cholestatic Jaundice

Proteins: Albumin: Decreased – advanced cirrhosis & signify severe hepatic dysfunction. [slideshare.net]

Serum albumin and globulin will change little in the acute phase but albumin will decrease and globulin increase in chronic disease. [patient.info]

Serum albumin is usually normal except in cirrhosis and chronic liver disease where albumin is decreased. [ncbi.nlm.nih.gov]

Liver Cirrhosis

When liver function decreases, the value of albumin also decreases. [otsuka.co.jp]

Increasing Child score, INR and decreasing albumin were correlated with TO. In addition, decompensated patients with ascites showed more abnormal TO and TS. [ncbi.nlm.nih.gov]

Thus, there is a frequent lack of BCAAs in LC patients, resulting in decreased albumin synthesis. [dx.doi.org]

Malabsorption Syndrome

Prothrombin time- Vitamin K level decreased 3. Serum albumin- Decreased (protein loss) 4. [histopathology-india.net]

Albumin is a general indicator of nutritional state. Low albumin can result from poor intake, decreased synthesis in cirrhosis, or protein wasting. [msdmanuals.com]

Serum albumin is decreased. D. Vitamin absorption: 1. Vitamin B12- Schilling test 2. Serum folate- Indicator of jejunal dysfunction 3. [histopathology-india.net]

Minimal Change Nephropathy

When albumin is excreted in the urine, its serum (blood) concentration decreases. Consequently, the plasma oncotic pressure reduces relative to the interstitial tissue. [en.wikipedia.org]

The precentage of cholesterol esters was not decreased. In case of recovery, the cholesterol seemed to return to normal values at a slower rate than the serum albumin. [pediatrics.aappublications.org]

A satisfactory response characterized by correction of hypoalbuminemia, clearance of proteinuria, and an increase of endogenous creatinine clearance occurred with corticosteroid [ncbi.nlm.nih.gov]

Primary Biliary Cirrhosis

albumin levels in the body Easy bruising or bleeding: The liver is responsible for producing blood clotting factors. [medicinenet.com]

[…] called spontaneous bacterial peritonitis (peritoneum=sac that contains the abdominal organs + itis=inflammation) Edema: Swelling of the legs may occur, again because of decreased [medicinenet.com]

[…] called spontaneous bacterial peritonitis (peritoneum=sac that contains the abdominal organs + itis=inflammation) Edema : Swelling of the legs may occur, again because of decreased [medicinenet.com]

Exfoliative Dermatitis

Common laboratory abnormalities found in ED patients include anemia, leukocytosis, lymphocytosis, eosinophilia, increased IgE, decreased serum albumin, and an elevated erythrocyte [plasticsurgerykey.com]

Hypoalbuminemia results, in part, from decreased synthesis or increased metabolism of albumin. [emedicine.medscape.com]

Systemic and potentially life-threatening complications include fluid and electrolyte imbalance, thermoregulatory disturbance, fever, tachycardia, high-output failure, hypoalbuminemia [plasticsurgerykey.com]

Alcoholic Hepatitis

[…] serum albumin level Increased serum IgA and IgG levels Decreased serum cholesterol level Decreased serum triiodothyronine level - Serum transaminases levels are often not [euroliver.org]

He was able to increase his albumin and decrease his international normalized ratio (INR) to the normal ranges, increase healthy eating and regain weight, and resolve the [hepatitis.va.gov]

Serum albumin may be decreased, prothrombin time prolonged and the international normalized ratio (INR) may be elevated; however, these values depend on the severity of the [elsevier.es]

Glomerulonephritis

Urinary protein exertion was decreased, and serum level of complement and albumin was increased. [ncbi.nlm.nih.gov]

When the liver is unable to compensate for the excreted proteins, serum protein levels, particular albumin and globulin, are decreased. [symptoma.com]

[…] kidney; characterized by decreased production of urine and by the presence of blood and protein in the urine and by edema. [onlinerecnik.com]

Multicentric Castleman's Disease

In each case, tocilizumab alleviated symptoms, including generalized fatigue, pyrexia, and alleviated biochemical abnormalities, including anemia, hypoalbuminemia, hypergammaglobulinemia [ncbi.nlm.nih.gov]

Indicators of inflammation were remarkable: she had extremely high levels of serum interleukin-6 (IL-6) (398 pg/ml) in addition to hypergammaglobulinemia and hypoalbuminemia [ncbi.nlm.nih.gov]

However, laboratory findings of anemia, hypoalbuminemia, polyclonal gammaglobulinemia, high C-reactive protein level, and elevated serum interleukin-6 level were consistent [ncbi.nlm.nih.gov]

Metastatic Liver Carcinoma

Diagnosis [ edit ] Hemoglobin decrease Liver function test : ALP elevated, bilirubin elevated, albumin decrease Carcinoembryonic antigen for colorectal secondaries Ultrasound [en.wikipedia.org]

Renal Amyloidosis

Serum protein electrophoresis showed a decrease in both total protein and total albumin without a monoclonal spike. [kjim.org]

The patient was put on Colchicine and anticoagulants seeing the major hypoalbuminemia. [ecco-ibd.eu]

Among the 23 patients with AA amyloidosis, after six months of treatment with colchicine, the proteinuria improved, serum albumin level increased and edema disappeared in [ncbi.nlm.nih.gov]

Liver Abscess

The size of abscess was correlated with leukocytes increase, albumin decrease, and time duration for body temperature normalization (all p p = 0.022). [nature.com]

[…] tests Complete blood count : neutrophilic leukocytosis, normocytic normochromic anemia Liver function tests : and enzymes: ↑ alkaline phosphatase ( 90% ), ↑ AST and ALT ;, hypoalbuminemia [amboss.com]

A worse prognosis may be expected when there is a delay in diagnosis; multiple organisms cultured from blood; jaundice; hypoalbuminemia; a pleural effusion; or other associated [enotes.tripod.com]

Pseudomembranous Colitis

Investigations FBC - Increased WBC LFT – decreased albumin EUC/CMP – electrolyte disturbance and renal dysfunction Lactate Stool cultures - unformed stool only AXR – thumbprinting [aci.health.nsw.gov.au]

On admission, leukocytosis was found in 79% of patients, > 20,000/mm3 in half of them; 60% were anemic, 60% had elevated erythrocyte sedimentation rate, and 78% had hypoalbuminemia [ncbi.nlm.nih.gov]

Features considered nonspecific but suggestive of Clostridium difficile infection include leukocytosis, hypoalbuminemia and faecal leukocytes and occult blood. [histopathology-india.net]

Acute Fatty Liver of Pregnancy

Albumin level was decreased in 88 % women and hypoglycemia was documented in 56 % women. [ncbi.nlm.nih.gov]

LABORATORY FINDINGS: all had raised transaminases and serum bilirubin (32.5-510.8 mumol/L), hypoalbuminemia (22.4-30.0 g/L), hypofibrinogenemia (< 180 mg/dl), prolonged prothrombin [ncbi.nlm.nih.gov]

The moderate elevation of transaminases and bilirubin levels, and hypoalbuminemia is compatible with AFLP; the presence of marked hypoglycemia in the metabolic panel, and [medicaljoyworks.com]

Polymyalgia Rheumatica

Anemia of chronic disease, leukocytosis, reactive thrombocytosis, and decreased albumin are also common. Alkaline phosphatase and hepatic enzymes may be elevated. [rheumaknowledgy.com]

An electrophoresis analysis using a blood sample revealed a decrease in albumin with no signs of monoclonal peaks. [revistanefrologia.com]

Serum albumin levels may be slightly decreased. • The creatine kinase level is normal; this finding helps differentiate PMR from polymyositis and other primary myopathic disorders [uspharmacist.com]

Food Allergy

Features of FPE are nonbloody diarrhea, malabsorption, protein-losing enteropathy, hypoalbuminemia, and failure to thrive. [ncbi.nlm.nih.gov]

Congenital Liver Cirrhosis

Decreased serum albumin and a prolonged PT directly reflect impaired hepatic synthesis—usually an end-stage event. Albumin can also be low when nutrition is poor. [merckmanuals.com]

Alterations of laboratory test results can represent physiologic changes of pregnancy an example of this is a decreased level of serum albumin and increased level of alkaline [clevelandclinicmeded.com]

Total protein and albumin levels, indicators of liver synthetic function, are decreased in only 5-10% of patients seen in the outpatient setting. [acc.org]

Burn Injury

The level of albumin is reduced, causing a decrease in the binding fraction of drugs which bind primarily with albumin, such as the benzodiazepines and the antiepileptic drugs [medbc.com]

Alkaline phosphatase is a zinc-dependent enzyme and can be decreased in zinc deficiency. [dermatologyadvisor.com]

The real problem in burn treatment is hypoalbuminemia. [ncbi.nlm.nih.gov]

Gastritis

Partial or complete gastric resection may be necessary in cases of severe hypoalbuminemia. [web.archive.org]

Variable findings sometimes associated with GHG include low levels of the protein albumin (hypoalbuminemia), which may result in fluid accumulation (edema) in the stomach. [rarediseases.org]

Hypoalbuminemia (the most consistent laboratory abnormality) caused by GI protein loss may be present (protein-losing gastropathy). [web.archive.org]

Acute Inflammation

"Negative" acute-phase proteins Protein Immune system function of decrease Albumin Transferrin Transthyretin Transcortin Decreased binding of cortisol, upregulation of inflammation [slideshare.net]