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2,403 Possible Causes for Albumin Decreased, Complete Blood Count Abnormal, Mutation in the CDK6 Gene

  • Gastric Adenocarcinoma

    In Pt2, the SETBP1 gene (p.S944N) was mutated, as it is in myeloid malignancies ( 20 ), together with amplification of AKAP9 and CDK6 (cyclin-dependent kinase 6).[pnas.org] Figure 5: Integrated molecular description of gastric cancer. a, Mutations, copy-number changes and translocations for select genes are shown across samples organized by molecular[nature.com] Intriguingly, mutations of the gene encoding the voltage-dependent calcium channel protein, CACNA1D p.V529G , was found in both Pt1 and Pt2.[pnas.org]

  • Third Trimester Pregnancy

    The concomitant phenomenon of a third trimester pregnancy with a significant degree of pelvic organ prolapse is extremely rare. We report on a patient with pelvic organ prolapse complicating third trimester pregnancy treated by concomitant cesarean hysterectomy and abdominal sacrocolpopexy. A 30-year-old woman,[…][ncbi.nlm.nih.gov]

    Missing: Mutation in the CDK6 Gene
  • Polymyalgia Rheumatica

    blood count, measurement of inflammatory markers, blood chemistries, urinalysis, and chest radiography, along with any test needed based on symptoms. 42 TEMPORAL ARTERY BIOPSY[aafp.org] Anemia of chronic disease, leukocytosis, reactive thrombocytosis, and decreased albumin are also common. Alkaline phosphatase and hepatic enzymes may be elevated.[rheumaknowledgy.com] An electrophoresis analysis using a blood sample revealed a decrease in albumin with no signs of monoclonal peaks.[revistanefrologia.com]

    Missing: Mutation in the CDK6 Gene
  • Hepatocellular Carcinoma

    Routine liver function tests, coagulation parameters, complete blood count, and serum chemistries should be ordered for any patient with decompensated liver disease and suspicion[clinicaladvisor.com] Discussions In this case study, it was observed that the levels of total protein decreased with concomitant decrease in albumin levels and increased in globulin levels.[jbiomeds.com] Common lab abnormalities include: thrombocytopenia, hypoalbuminemia, hyperbilirubinemia, and an elevated serum INR.[clinicaladvisor.com]

    Missing: Mutation in the CDK6 Gene
  • Cronkhite-Canada Syndrome

    Total protein was within normal range, but the serum albumin level was moderately decreased [3.1g/dl, normal range 4.0–5.0g/dl].[academic.oup.com] Serum protein electrophoresis revealed a decrease in the albumin fraction in 50% of patients and elevation of α 1, globulin in 59.1%.[kjim.org] Laboratory evaluation revealed normochromic, normocytic anemia and decreased serum levels of ionized calcium (4.4 mg/dL; normal, 4.7 to 5.4 mg/dL), albumin (3.0 g/dL; normal[thefreelibrary.com]

    Missing: Mutation in the CDK6 Gene
  • Inflammatory Bowel Disease Type 1

    Blood cell counts: Complete blood count ( CBC ) blood test may show abnormalities and may indicate anemia or inflammation.[emedicinehealth.com] As seen in Table 4, improvements in hemoglobin (Hgb), white blood cell count, erythrocyte sedimentation rate, and albumin were observed during the course of the study and[journals.lww.com] Blood tests may be ordered to test for Crohn's disease. The purpose of these is to detect inflammation or nutritional deficiencies.[emedicinehealth.com]

    Missing: Mutation in the CDK6 Gene
  • Septicemia

    Following evidence-based guidelines and formal protocols for timely diagnosis and treatment of sepsis has recently been shown to decrease mortality and length of stay in the[merckmanuals.com] The SAFE study indicated albumin administration was safe and equally effective as crystalloid [ 65 ].[doi.org] Some clinicians add albumin to the initial fluid bolus in patients with severe sepsis or septic shock; albumin is more expensive than crystalloid but is generally a safe complement[merckmanuals.com]

    Missing: Mutation in the CDK6 Gene
  • Multiple Myeloma

    A complete blood count, peripheral blood smear, chemistry screen including calcium and creatinine determinations, β 2 -microglobulin (β 2 M), lactate dehydrogenase and routine[doi.org] In the blood of patients with multiple myeloma, the amount of beta-2-microglobulin is increased and the amount of albumin is decreased.[my.clevelandclinic.org] Sβ 2 M reflects not only tumor mass and renal function but also other as yet unknown parameters, possibly including immune function. 7, 34, 35 The specific cause of decreased[doi.org]

    Missing: Mutation in the CDK6 Gene
  • Systemic Lupus Erythematosus

    Each of these are detectable with standard complete blood count testing ( CBC ).[medicinenet.com] In some systemic lupus erythematosus studies, heart rate variability was found to correlate with inflammatory markers and albumin levels.[ncbi.nlm.nih.gov] count (RBC), or platelet count on routine complete blood count testing; leukopenia, anemia , and thrombocytopenia, respectively.[medicinenet.com]

    Missing: Mutation in the CDK6 Gene
  • Lipoid Nephrosis

    A complete blood count shows low hemoglobin and elevated serum creatinine.[medbullets.com] It has been shown that the simple sugar galactose blocks the effect of FSGS serum on albumin permeability in vitro and decreases permeability activity when administered to[doi.org] When albumin is excreted in the urine, its serum (blood) concentration decreases. Consequently, the plasma oncotic pressure reduces relative to the interstitial tissue.[en.wikipedia.org]

    Missing: Mutation in the CDK6 Gene