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2,733 Possible Causes for Albumin Decreased, Gastrointestinal Hemorrhage, Mutation in the CDK6 Gene

  • Gastric Adenocarcinoma

    In Pt2, the SETBP1 gene (p.S944N) was mutated, as it is in myeloid malignancies ( 20 ), together with amplification of AKAP9 and CDK6 (cyclin-dependent kinase 6).[pnas.org] Figure 5: Integrated molecular description of gastric cancer. a, Mutations, copy-number changes and translocations for select genes are shown across samples organized by molecular[nature.com] Intriguingly, mutations of the gene encoding the voltage-dependent calcium channel protein, CACNA1D p.V529G , was found in both Pt1 and Pt2.[pnas.org]

  • Liver Cirrhosis

    CONCLUSION: Patients with liver cirrhosis and upper gastrointestinal bleeding hemorrhage from a variety of lesions.[ncbi.nlm.nih.gov] When liver function decreases, the value of albumin also decreases.[otsuka.co.jp] Unfortunately, the risk of recurrent bleeding affects 40% of patients within 6 weeks (mainly 1 week) from gastrointestinal hemorrhage.[ncbi.nlm.nih.gov]

    Missing: Mutation in the CDK6 Gene
  • Cronkhite-Canada Syndrome

    Total protein was within normal range, but the serum albumin level was moderately decreased [3.1g/dl, normal range 4.0–5.0g/dl].[academic.oup.com] Serum protein electrophoresis revealed a decrease in the albumin fraction in 50% of patients and elevation of α 1, globulin in 59.1%.[kjim.org] Laboratory evaluation revealed normochromic, normocytic anemia and decreased serum levels of ionized calcium (4.4 mg/dL; normal, 4.7 to 5.4 mg/dL), albumin (3.0 g/dL; normal[thefreelibrary.com]

    Missing: Mutation in the CDK6 Gene
  • Inflammatory Bowel Disease Type 1

    hemorrhage, short bowel syndrome, or end-stage liver disease secondary to primary sclerosing cholangitis.[oadoi.org] As seen in Table 4, improvements in hemoglobin (Hgb), white blood cell count, erythrocyte sedimentation rate, and albumin were observed during the course of the study and[journals.lww.com] […] severe CD complicated by intraabdominal abscess, bowel perforation, sepsis, cardiovascular complications, postoperative complications, cancer, thromboembolic complications, gastrointestinal[oadoi.org]

    Missing: Mutation in the CDK6 Gene
  • Acute Liver Failure

    The use of gastrointestinal hemorrhage prophylaxis with a histamine-2 (H2) blocker, proton pump inhibitor, or sucralfate is recommended.[en.wikipedia.org] In a post hoc analysis, combination of albumin and bioartificial liver support systems resulted in decreased mortality (relative risk, 0.80; 95% CI, 0.65–0.98).[gastro.org] Rimola A, Bory F, Teres J, Perez-Ayuso RM, Arroyo V, Rodes J (1985) Oral, nonabsorbable antibiotics prevent infection in cirrhotics with gastrointestinal hemorrhage.[link.springer.com]

    Missing: Mutation in the CDK6 Gene
  • Colonic Angiodysplasia

    Abstract Colonic angiodysplasia (AD) is an important vascular lesion responsible for approximately 6.0% of cases of lower gastrointestinal hemorrhage.[ncbi.nlm.nih.gov] Masive lower gastrointestinal hemorrhage in a patient with colonic angiodysplasia. Int J Surg 2009;20. 6. Foutch PG. Angiodysplasias of the gastrointestinal tract.[njcponline.com] Gastrointestinal hemorrhage in patients with systemic sclerosis and CREST syndrome. Am J Gastroenterol. 1998 Sep. 93(9):1453-6. [Medline].[emedicine.medscape.com]

    Missing: Mutation in the CDK6 Gene
  • Primary Biliary Cirrhosis

    This patient remains alive but experienced an emergent gastrointestinal hemorrhage.[ncbi.nlm.nih.gov] albumin levels in the body Easy bruising or bleeding: The liver is responsible for producing blood clotting factors.[medicinenet.com] hemorrhage.[disabilitysecrets.com]

    Missing: Mutation in the CDK6 Gene
  • Ulcerative Colitis

    […] colitis, microscopic colitis Obstruction: hernia, intussusception, volvulus, post-surgical adhesions, tumors, severe constipation, hemorrhoids Vascular: embolism, thrombosis, hemorrhage[en.wikipedia.org] This procedure is necessary in the event of: exsanguinating hemorrhage, frank perforation, or documented or strongly suspected carcinoma.[en.wikipedia.org] Vascular: occlusive intestinal ischemia, usually caused by thromboembolism of the superior mesenteric artery By system [ edit ] A more extensive list includes the following: Gastrointestinal[en.wikipedia.org]

    Missing: Mutation in the CDK6 Gene
  • Amyloidosis

    The causes of death in the eprodisate group were ischemic stroke in two patients, the nephrotic syndrome in one patient, gastrointestinal hemorrhage in one, and pneumonia[doi.org] If the patient shows significant renal involvement with a decrease in the concentration of albumin as a result of the nephrotic syndrome, very high doses of diuretic drugs[revespcardiol.org] CASE REPORT Localized gastrointestinal amyloidosis presenting with protein-losing enteropathy and massive hemorrhage Bárbara Corrêa, Cristiane Kibune Nagasako, Ciro Garcia[scielo.isciii.es]

    Missing: Mutation in the CDK6 Gene
  • Cystic Fibrosis

    Unfortunately, he succumbed to an acute upper gastrointestinal hemorrhage.[ncbi.nlm.nih.gov] Complications of liver enlargement may include internal hemorrhaging, abdominal fluid (ascites), spleen enlargement, and liver failure.[medical-dictionary.thefreedictionary.com] Other gastrointestinal symptoms can include: prolapsed rectum, in which part of the rectal lining protrudes through the anus; intestinal obstruction; and rarely, intussusception[medical-dictionary.thefreedictionary.com]

    Missing: Mutation in the CDK6 Gene

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