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10 Possible Causes for Albumin Decreased, Immunoglobulin G Increased, Virus Associated Hemophagocytic Syndrome

  • Chronic Active Hepatitis B

    Corticosteroid therapy also lead to improvement in biochemical abnormalities (decrease bilirubin and aminotransferase level and increase albumin) as well as decrease in the[hepatitiscentral.com] Bone marrow biopsy showed hypocellularity, histiocytic hyperplasia, and hemophagocytosis consistent with a virus-associated hemophagocytic syndrome (VAHS).[ncbi.nlm.nih.gov] Laboratory testing should show evidence of abnormal liver chemistry tests, increased total immunoglobulin G (IgG) or gamma-globulin levels and autoantibodies.[clinicaladvisor.com]

  • Chronic Active Hepatitis

    Corticosteroid therapy also lead to improvement in biochemical abnormalities (decrease bilirubin and aminotransferase level and increase albumin) as well as decrease in the[hepatitiscentral.com] Bone marrow biopsy showed hypocellularity, histiocytic hyperplasia, and hemophagocytosis consistent with a virus-associated hemophagocytic syndrome (VAHS).[ncbi.nlm.nih.gov] Laboratory testing should show evidence of abnormal liver chemistry tests, increased total immunoglobulin G (IgG) or gamma-globulin levels and autoantibodies.[clinicaladvisor.com]

  • Lupus Nephritis

    In addition, patients may also have evidence of nephrotic syndrome with lower extremity and peri-orbital edema as well as decreased serum albumin.[clinicaladvisor.com] However, she suffered Epstein- Barr virus (EBV)-associated hemophagocytic syndrome (HPS) twice, and in each case she was treated with anticancer drugs and achieved a complete[ncbi.nlm.nih.gov] Or sCr Plus inactive urinary sediment ( Plus serum albumin 30 g/dL (GEAS) Partial response 50% decrease in proteinuria, to at least sub-nephrotic levels (except CARRA) Plus[ndt.oxfordjournals.org]

  • Hodgkin Lymphoma

    Hodgkin lymphoma-associated hemophagocytic syndrome: a disorder strongly correlated with Epstein-Barr virus. Clin Infect Dis. 2008 Aug 15. 47(4):531-4. [Medline].[emedicine.medscape.com]

  • Infectious Mononucleosis

    The most commonly seen abnormalities in the paper electrophoretic patterns of sera obtained from patients with infectious mononucleosis were decreased albumin, increased gamma[link.springer.com] Severe chronic active Epstein-Barr virus infection accompanied by virus-associated hemophagocytic syndrome, cerebellar ataxia and encephalitis.[emedicine.medscape.com] Epstein-Barr virus-associated hemophagocytic syndrome and fatal infectious mononucleosis. Am J Hematol. 1996 Oct. 53(2):111-5. [Medline].[emedicine.medscape.com]

  • Infectious Mononucleosis Hepatitis

    Severe chronic active Epstein-Barr virus infection accompanied by virus-associated hemophagocytic syndrome, cerebellar ataxia and encephalitis.[emedicine.medscape.com] Gradually, the aminotransferase levels decreased and after 2 weeks became normal; tests for EBV DNA became undetectable; and the bilirubin and albumin levels returned to normal[gastrohep.com] Commonly, patients and physicians equate increased EBV immunoglobulin G (IgG) VCA antibody titers with chronic infectious mononucleosis or CFS because more than 90% of the[emedicine.medscape.com]

  • Autoimmune Hepatitis

    Virus-, drug- and lymphoma-associated hemophagocytic syndrome (HPS) was ruled out. Therefore, the patient was diagnosed with autoimmune-associated HPS (AAHS).[ncbi.nlm.nih.gov] […] levels, and significantly decreased after corticosteroid treatment.[ncbi.nlm.nih.gov] It is characterized by inflammatory liver histology, elevated transaminase level, circulating nonorgan-specific autoantibodies, and increased level of immunoglobulin G in[ncbi.nlm.nih.gov]

  • Disseminated Cytomegalovirus Infection

    Infection-associated hemophagocytic syndrome (IAHS) is observed with viral infections (CMV, Epstein Barr virus, human herpes virus 8, human herpes virus 6, Parvovirus B19[intechopen.com] Immunoglobulin G (IgG) antibody production occurs within a few weeks of IgM increase[ 16 ].[wjgnet.com] CMV associated Hemophagocytic Syndrome (HPS) CMV hemophagocytic syndrome, also referred as macrophage activation syndrome (MAS) or haemophagocytic lymphohistiocytosis (HLH[intechopen.com]

  • Cytomegalovirus Colitis

    […] hgb (9.2 g/dL), sodium (130 mEq/L), and albumin (2.1 g/dL).[ispub.com] Infection-associated hemophagocytic syndrome (IAHS) is observed with viral infections (CMV, Epstein Barr virus, human herpes virus 8, human herpes virus 6, Parvovirus B19[intechopen.com] Immunoglobulin G (IgG) antibody production occurs within a few weeks of IgM increase[ 16 ].[wjgnet.com]

  • Dengue Fever

    In these cases, the pathogenesis of hemorrhagic diathesis is the result of severe liver damage leading to decreased production of coagulation proteins and albumin.[dx.doi.org] ’s records revealed that she met the clinical case definition for hemophagocytic lymphohistiocytosis, a hyperinflammatory syndrome that is sometimes associated with dengue[emedicine.com] Collenberg et al. reported that the prevalence of antibodies against DENV determined by immunoglobulin G indirect ELISA among a sample of pregnant women and blood donors ([doi.org]