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3,574 Possible Causes for Albumin Decreased, Mutation in the CDK6 Gene, Splenomegaly

  • Liver Cirrhosis

    We performed LS in 83 patients with massive splenomegaly ( 30 cm) secondary to portal hypertension and liver cirrhosis.[ncbi.nlm.nih.gov] When liver function decreases, the value of albumin also decreases.[otsuka.co.jp] Increasing Child score, INR and decreasing albumin were correlated with TO. In addition, decompensated patients with ascites showed more abnormal TO and TS.[ncbi.nlm.nih.gov]

    Missing: Mutation in the CDK6 Gene
  • Portal Cirrhosis

    Liver cirrhosis: Liver cirrhosis with an inhomogeneous liver with irregular contour and ascites and splenomegaly Liver cirrhosis: Liver cirrhosis with an irregular liver contour[ultrasoundcases.info] […] platelets Splenomegaly Reduced hepatic production of thrombopoietin Direct toxic effect of alcohol on the bone marrow Albumin Decreased in advanced cirrhosis Decreased hepatic[pathophys.org] Albumin will decrease and this is a marker for reduced synthetic function of the liver.[kenhub.com]

    Missing: Mutation in the CDK6 Gene
  • Septicemia

    Following evidence-based guidelines and formal protocols for timely diagnosis and treatment of sepsis has recently been shown to decrease mortality and length of stay in the[merckmanuals.com] The SAFE study indicated albumin administration was safe and equally effective as crystalloid [ 65 ].[doi.org] Some clinicians add albumin to the initial fluid bolus in patients with severe sepsis or septic shock; albumin is more expensive than crystalloid but is generally a safe complement[merckmanuals.com]

    Missing: Mutation in the CDK6 Gene
  • Systemic Lupus Erythematosus

    […] relapsing illness, with a variety of different presentations. [ 5 , 6 ] Symptoms and signs are often nonspecific - eg, fatigue (can be severe and debilitating), malaise, fever, splenomegaly[patient.info] In some systemic lupus erythematosus studies, heart rate variability was found to correlate with inflammatory markers and albumin levels.[ncbi.nlm.nih.gov] […] relapsing illness, with a variety of different presentations. [ 5, 6 ] Symptoms and signs are often nonspecific - eg, fatigue (can be severe and debilitating), malaise, fever, splenomegaly[patient.info]

    Missing: Mutation in the CDK6 Gene
  • Alcoholic Hepatitis

    Image studies showed an extremely enlarged fatty liver and splenomegaly.[ncbi.nlm.nih.gov] He was able to increase his albumin and decrease his international normalized ratio (INR) to the normal ranges, increase healthy eating and regain weight, and resolve the[hepatitis.va.gov] Splenomegaly is uncommon. Ascites and hepatic encepalopathy are common in severe disease but varices are not common.[euroliver.org]

    Missing: Mutation in the CDK6 Gene
  • Primary Biliary Cirrhosis

    […] of the caudate lobe hepatic surface irregularity due to regenerative nodules regional lymphadenopathy: tends to dominate in the gastrohepatic ligament and porta hepatis 4 splenomegaly[radiopaedia.org] albumin levels in the body Easy bruising or bleeding: The liver is responsible for producing blood clotting factors.[medicinenet.com] The multivariate analysis identified two independent predictive factors: low albumin level and splenomegaly ( Table 3 ).[nejm.org]

    Missing: Mutation in the CDK6 Gene
  • Secondary Amyloidosis

    Hepatomegaly, splenomegaly, and autonomic neuropathy frequently occur as the disease progresses; cardiomyopathy occurs rarely.[bu.edu] However, recently, after 18 months of anakinra treatment, her proteinuria gradually increased and albumin levels decreased.[ncbi.nlm.nih.gov] Oedema accompanied by proteinuria was present in 88% of the cases, hepatomegaly in 17%, and splenomegaly in 11%.[ncbi.nlm.nih.gov]

    Missing: Mutation in the CDK6 Gene
  • Viral Hepatitis

    An ultrasound obtained for evaluation of a prolonged prothrombin time and decreased serum albumin level showed a suspicious nodular lesion in the left lobe of the liver.[ncbi.nlm.nih.gov] Many other conditions also affect albumin level. Total protein – albumin and all other proteins in blood; may be decreased with severe liver disease.[labtestsonline.org] Since albumin is produced by the liver, its level can decrease with loss of liver function; however, this typically occurs only when the liver has been severely affected.[labtestsonline.org]

    Missing: Mutation in the CDK6 Gene
  • Amyloidosis

    PATIENT CONCERNS: We reported two cases with ApoA-1 amyloidosis, a 64-year-old man suffering from nephrotic syndrome and a 40-year-old man with nephrotic syndrome and splenomegaly[ncbi.nlm.nih.gov] If the patient shows significant renal involvement with a decrease in the concentration of albumin as a result of the nephrotic syndrome, very high doses of diuretic drugs[revespcardiol.org] Hepatomegaly is a frequent finding, 39 and although palpable splenomegaly is rare, evidence of splenic dysfunction is often apparent (table 5 ).[pmj.bmj.com]

    Missing: Mutation in the CDK6 Gene
  • Felty's Syndrome

    Computed tomography of the pelvis led to an incorrect diagnosis of malignancy, while radionuclide imaging using Tc-99m sulfur colloid confirmed the diagnosis of ectopic splenomegaly[ncbi.nlm.nih.gov] Chemistry tests are usually normal in rheumatoid arthritis with the exception of a slight decrease in albumin and increase in total protein reflecting the chronic inflammatory[hopkinsarthritis.org] Abstract The syndrome of atrophic polyarthritis occurring in an adult, associated with fever, secondary anemia, leukopenia and splenomegaly, was described by Felty 1 in 1924[annals.org]

    Missing: Mutation in the CDK6 Gene

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