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1,333 Possible Causes for Aldehyde, metabolism

  • Xanthinuria

    […] oxypurinol, although there was a slight metabolizing of prazinamide into 5-hydroxypyrazinamide.[ncbi.nlm.nih.gov] […] lack aldehyde oxidase activity.[emedicine.com] The purine metabolism of four cases with marked hypouricemia (serum uric acid concentration of less than 0.018 mmol/l) from three Japanese families was investigated.[ncbi.nlm.nih.gov]

  • Osteoporosis

    IFNA8, IFNA13, IFNA14, IFNA16, IFNA17, IFNA21 , Interferon α proteins [ 36 ] PIK3C3 Phosphatidylinositol 3-kinase catalytic subunit type 3 [ 36 ] Other pathways ALDH7A1 Aldehyde[doi.org] […] with respect to BMD at different sites and ultrasound transmission through the peripheral skeleton, and to use PTH, total serum calcium, and biochemical markers of bone metabolism[doi.org] In order to improve the field of metabolic bone disease treatment, Dr.[centerforboneresearch.com]

  • Sjogren-Larsson Syndrome

    FALDH is an enzyme component of fatty alcohol:NAD oxidoreductase (FAO), which is necessary for fatty alcohol metabolism.[ncbi.nlm.nih.gov] Toxicity of long-chain aldehydes for FALDH-deficient cells decreased almost to the level of unaffected keratinocytes.[ncbi.nlm.nih.gov] […] gene for fatty aldehyde dehydrogenase (FALDH) that result in deficient enzyme activity and impaired oxidation of long-chain aliphatic aldehydes derived from fatty alcohol metabolism[ommbid.mhmedical.com]

  • Aldehyde

    Some aldehydes are substrates for aldehyde dehydrogenase enzymes which metabolize aldehydes in the body.[en.wikipedia.org] Metabolism, Covance Laboratories Ltd., Otley Road, Harrogate, North Yorkshire, HG3 1PY, UK. 3 Department of Drug Metabolism, Covance Laboratories Inc., Madison, Wisconsin[ncbi.nlm.nih.gov] The combined organics were dried over Na2SO4, filtered and concentrated in vacuo to give aldehyde compound as a yellow solid (251 mg, 88%).[organic-reaction.com]

  • Xanthinuria Type 1

    Arabinoside 647 Role of Deoxycytidine Kinase dCK Thymidine Kinase 2 TK2 657 Increased Activity of Cytidine Triphosphate Synthetase in Pediatric Acute 667 5FU Prodrugs 677 Metabolic[books.google.com] […] allopurinol to oxipurinol during an allopurinol loading test for determining the type of classical xanthinuria revealed that the patients had classical type 1 xanthinuria, because aldehyde[ncbi.nlm.nih.gov] Allopurinol was metabolized to oxypurinol and pyrazinamide to 5-hydroxypyrazinamide in spite of no activity of xanthine oxidase, suggesting that aldehyde oxidase converted[ncbi.nlm.nih.gov]

  • Influenza

    Infectivity of the virion is easily inactivated by all alcoholic disinfectants, chlorine, aldehydes and temperature above 70 C. Sources www.gov.uk/...[news-medical.net] In addition, the metabolism of oseltamivir is different in rats than in humans. A key component of influenza therapy is the possibility for development of resistance.[ncbi.nlm.nih.gov] We observed an inverse correlation between influenza virulence and G2/M checkpoint control and glutathione metabolism.[doi.org]

  • Disulfiram

    Thus it seems unlikely that the previously observed protective effects of disulfiram against acetaminophen-induced hepatotoxicity in animals due to inhibition of metabolism[doi.org] Disulfiram (DSF), an inhibitor of aldehyde dehydrogenase, is currently in clinical use for treating alcoholism.[ncbi.nlm.nih.gov] The influence of disulfiram on theophylline metabolism was studied in 20 recovering alcoholics.[ncbi.nlm.nih.gov]

  • Xanthinuria Type 2

    Also Known As Xanthine dehydrogenase and xanthine aldehyde oxydase dual deficiency[codelay.com] Arabinoside 647 Role of Deoxycytidine Kinase dCK Thymidine Kinase 2 TK2 657 Increased Activity of Cytidine Triphosphate Synthetase in Pediatric Acute 667 5FU Prodrugs 677 Metabolic[books.google.de] In addition, XAN2 patients cannot metabolize allopurinol into oxypurinol due to dual deficiency of xanthine dehydrogenase and aldehyde oxidase.[malacards.org]

  • Deficiency of Sulfite Oxidase

    Encephalopathy without metabolic acidosis 174 Urea cycle enzyme defects UCED 175 Nonketotic hyperglycinemia NKHG 179 Pyridoxinedependent seizures 180 Peroxisomal disorders[books.google.de] The cofactor is essential for the function of the human enzymes sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase.[ommbid.mhmedical.com] Molybdenum cofactor is associated with the enzymes sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase (see the image below). [1] Molybdenum cofactor deficiency.[emedicine.medscape.com]

  • Sunburn

    Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes . Free Radic Biol Med 1991 ; 11 : 81 – 128 . 18 .[doi.org] Ultraviolet (UV) B-induced hydrolysis of membrane phospholipids releases polyunsaturated fatty acids, and their subsequent metabolism by cyclooxygenases (COXs) and lipoxygenases[ncbi.nlm.nih.gov] UVR activates release of membrane fatty acids and upregulates their metabolism by cyclooxygenases (COX) and lipoxygenases (LOX) to different eicosanoids.[ncbi.nlm.nih.gov]

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