Increased levels of aldosterone in the blood are indicative of hyperaldosteronism which, in turn, may be caused by adrenal disease and a variety of other conditions.
Most common diseases
Adrenocortical Carcinoma
From the 24-h urine collection sample, urine aldosterone and urine cortisol levels were greatly increased. [ncbi.nlm.nih.gov]
Laboratory testing showed increased levels of aldosterone, renin, cortisol, testosterone and androstenedione. [ncbi.nlm.nih.gov]
[…] body hair (especially on the face), pubic hair, acne, deepening of the voice, and enlarged clitoris (females) Symptoms of increased aldosterone are the same as symptoms of [nlm.nih.gov]
Hyperaldosteronism
Both these pathological conditions are responsible for the increased aldosterone production. [symptoma.com]
High systemic aldosterone levels result in increased sodium reabsorption and potassium secretion in the collecting ducts of the kidney, which leads to the retention of water [amboss.com]
[…] of angiotensin and aldosterone is increased. [britannica.com]
Conn Syndrome
Regardless of the cause, aldosterone is produced despite low renin levels Increased aldosterone can lead to hypokalaemia, increased blood pH (alkalosis), and high blood pressure [labtestsonline.org.au]
Regardless of the cause, aldosterone is produced despite low renin levels Increased aldosterone can lead to hypokalaemia, increased blood pH ( alkalosis ), and high blood [labtestsonline.org.au]
If adrenal hyperplasia triggers CS, plasma aldosterone levels should increase. [symptoma.com]
Familial Hyperaldosteronism Type 1
During posture, aldosterone increased in one but decreased in both other GRA patients. [ncbi.nlm.nih.gov]
Glucocorticoid remediable aldosteronism also describable as aldosterone synthase hyperactivity, is an autosomal dominant disorder in which the increase in aldosterone secretion [en.wikipedia.org]
Hypertension, increased aldosterone secretion and low plasma renin activity relieved by dexamethasone. Can Med Assoc J 1966 ;95:1109-19. [ Links ] 2. [doi.org]
Hypoaldosteronism
One hour after administration of 0.25 mg i.m. cosyntropin, cortisol increased normally, aldosterone increased from 220 to 360 pM, and 18-OHB increased from 3700 to 4800 pM [ncbi.nlm.nih.gov]
Aldosterone increases this transport and excretion of potassium ions. [hubpages.com]
In 1977, potassium, baseline cortisol, aldosterone, and renin activity were normal; renin activity increased normally with posture; and cortisol responded normally to ACTH [ncbi.nlm.nih.gov]
Secondary Aldosteronism
Renin from Juxtaglomerulo apparatus Increased Aldosterone (secondary aldosteronism) Increased sodium and water retention [pathology-ii.2865597.n2.nabble.com]
Shazy ĎŐŃ'Ť ĹŐŚĔ ĤŐРĔ Administrator Global Moderator Forum Moderator Reputation: 13 Primary Aldosteronism Increase intravascular Volume Decrease RENIN Level Do not have pedal [forum.pfmsg.com]
Development of hypostases is promoted also by other factors causing a secondary aldosteronism: increase of activity of system a renin — angiotensin and decrease in an inactivation [infomeds.net]
Essential Hypertension
BACKGROUND: There is conflicting evidence, relying on heterogeneous studies, as to whether aldosterone excess is responsible for an increased risk of cardiovascular and cerebrovascular [ncbi.nlm.nih.gov]
thirst/ADH and aldosterone Increased sodium reabsorption in the kidneys (DCT and CD) Increased blood pressure. [en.wikipedia.org]
We concluded that she had essential hypertension associated with primary aldosteronism. [ncbi.nlm.nih.gov]
Bartter's Disease
[…] potassium excretion occurs as a result of increased production of aldosterone. [britannica.com]
[…] system increases. 1 Prostaglandins increase as a consequence of volume contraction, and this increase may itself stimulate renin secretion. 2 Unfortunately, prostaglandins [nejm.org]
Increased production of aldosterone was subsequently associated with excessive potassium excretion. [britannica.com]
Hyperkalemia
[…] release) These all increase K uptake by the Na/K pump. [sharinginhealth.ca]
After this change, the urinary potassium concentration and the aldosterone and plasma renin activity increased. [ncbi.nlm.nih.gov]
Increased urinary loses – potassium excretion occurs mostly in the distal nephrons and increased losses may be seen in diuretic use, increased aldosterone secretion, nonreabsorbable [acls.com]
Hyporeninemic Hypoaldosteronism
PRA increased to a lesser degree in two other patients and plasma aldosterone slightly increased. Five showed no response. [ncbi.nlm.nih.gov]
Under ACTH-infusion only marked increases in aldosterone were observed in one patient whereas cortisol responded normally in all diabetics tested. [ncbi.nlm.nih.gov]
[…] and/or hypotension) Serum Aldosterone Technique : should be performed after the administration of a loop diuretic or 3 hrs in the upright position (as these will increase [mdnxs.com]