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665 Possible Causes for Alkaline Phosphatase Increased, Autoimmune Disease

  • Infectious Mononucleosis

    Abstract Epstein-Barr virus and vitamin D both have been implicated in the pathogenesis of autoimmune diseases, especially multiple sclerosis (MS).[ncbi.nlm.nih.gov] disease.[dx.doi.org] Abstract Follicular helper T (Tfh) cells are recognized as a distinct CD4helper T cell subset, and mainly dysregulated in the autoimmune disease, whether it plays a role in[ncbi.nlm.nih.gov]

  • Autoimmune Hepatitis

    Abstract Autoimmune polyglandular syndrome (APS) is a combination of different autoimmune diseases.[ncbi.nlm.nih.gov] phosphatase – In 80-90% of patients; a sharp increase in the alkaline phosphatase values during the course of autoimmune disease may reflect the development of primary sclerosing[emedicine.com] In severe cases, a liver transplant may be needed. [3] People with another autoimmune disease or a family history of autoimmune disease may be more likely to develop autoimmune[rarediseases.info.nih.gov]

  • Graves Disease

    Autoimmune Factors Graves’ disease is considered an antibody-mediated autoimmune disorder.[elaine-moore.com] The association of Moyamoya disease and Graves disease in these cases is explained by the same autoimmune mechanism ( 10 ).[ajnr.org] Graves' disease is an autoimmune condition that results in overstimulation of the thyroid gland.[emedicinehealth.com]

  • Primary Biliary Cirrhosis

    OBJECTIVES: Autonomic dysfunction is closely associated with autoimmune diseases (AID) including primary biliary cirrhosis (PBC).[ncbi.nlm.nih.gov] We had also observed in the other three groups of patients that the average of the values of γ-glutamyl transpeptidase and alkaline phosphatase increases with the increase[ncbi.nlm.nih.gov] alkaline phosphatase levels results in an improvement of cholestasis as compared to placebo, with a parallel decrease of aminotransferases and immunoglobulin M, as well as[ncbi.nlm.nih.gov]

  • Reynold Syndrome

    autoimmune disorders 4A43 Overlap or undifferentiated non-organ specific systemic autoimmune disease H01133 Reynolds syndrome Gene LBR [HSA: 3930 ] [KO: K19532 ] Other DBs[genome.jp] The liver disease is characterized by pruritis, jaundice, hepatomegaly, increased serum alkaline phosphatase and positive serum mitochondrial autoantibodies, all consistent[malacards.org] Overview Reynolds syndrome is a rare autoimmune disease, consisting of the combination of primary biliary cirrhosis and progressive systemic sclerosis.[checkorphan.org]

  • Primary Sclerosing Cholangitis

    […] pathogenesis, and position PSC as an autoimmune disease.[ncbi.nlm.nih.gov] Liver function tests are usually abnormal (increased serum alkaline phosphatase (ALP) most commonly) and the bilirubin level can be raised with biliary obstruction.[royalfree.nhs.uk] Serum alkaline phosphatase levels tend to increase 3-5 times than normal.[symptoma.com]

  • Liver Disease

    About Autoimmune Liver Disease Autoimmune liver diseases are typically chronic conditions.[mountsinai.org] […] bilirubin (without increase in alkaline phosphatase) (See web-based course on liver function test abnormalities .)[hiv.va.gov] Screening and detection tests include: Alanine aminotransferase (ALT) – an enzyme found mainly in the liver; best test to detect hepatitis Alkaline phosphatase (ALP) – an[labtestsonline.org]

  • Sweet Syndrome

    BACKGROUND: Pemphigus vulgaris is an autoimmune blistering disease of the skin and mucous membranes. Sweet syndrome is an uncommon reactive neutrophilic dermatosis.[ncbi.nlm.nih.gov] Studies show a moderate neutrophilia (less than 50%), elevated ESR (greater than 30 mm/h) (90%), and a slight increase in alkaline phosphatase (83%).[en.wikipedia.org] Screening for underlying etiologies, including autoimmune disease, malignancy, and offending drugs, is important for targeted therapy.[ncbi.nlm.nih.gov]

  • Pharyngitis

    Post streptococcal glomerulonephritis-not prevented by treated of GABHS infection PANDAS-(Pediatric Autoimmune Neuropsychiatric Disease Associated with Streptococcus) Controversial[pedclerk.bsd.uchicago.edu] Alanine aminotransferase, alkaline phosphatase, aspartate aminotransferase, bilirubin, glucose, creatinine phosphokinase, gamma-glutamyltransferase, LDL cholesterol, lipids[medical-dictionary.thefreedictionary.com] SUMMARY: The gap between molecular markers of disease (correlation) and virulence mechanisms (causation) in the establishment of tissue tropisms for GAS infection currently[ncbi.nlm.nih.gov]

  • Vitamin D Deficiency

    Abstract Primary Sjögren's syndrome (pSS) is a chronic autoimmune disease characterized by progressive lymphocyte infiltration of the exocrine glands.[ncbi.nlm.nih.gov] Juvenile Paget's disease (JPD) is a rare heritable osteopathy characterized biochemically by markedly increased serum alkaline phosphatase (ALP) activity emanating from generalized[ncbi.nlm.nih.gov] Serum phosphate usually decreases, and serum alkaline phosphatase usually increases. Serum PTH may be normal or elevated.[merck.com]

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