Create issue ticket

27 Possible Causes for Alkaline Phosphatase Increased, Cryoglobulinemia, Yellow Discoloration of the Skin

  • Viral Hepatitis

    HCV RNA can be demonstrated in the tumor as well as in surrounding liver tissue although HCV RNA cannot be integrated in the hepatocytic DNA. 3--Essential cryoglobulinemia[meddean.luc.edu] The most notable symptom of acute viral hepatitis is jaundice, which is a yellow discoloration of the skin and the whites of the eyes.[patients.gi.org] Hepatosplenomegaly and laboratory evidence of mild to moderate hepatic dysfunction are the predominant features, with increased aminotransferases and alkaline phosphatase[doi.org]

  • Hepatitis B

    RESULTS: Clinical history, examinations, and laboratory results suggest HBV-associated cryoglobulinemia and vasculitis.[ncbi.nlm.nih.gov] Jaundice (a yellow discoloration of eyes and skin), which is usually a sign of liver damage, may not occur.[web.archive.org] […] serum alkaline phosphatase (4%), increased liver enzymes (2%) Local: Pain at injection site (4%) Neuromuscular & skeletal: Myalgia (10%), joint stiffness (2%) Renal: Increased[drugs.com]

  • Liver Cirrhosis

    […] non-organ-specific autoantibody production up to overt non-Hodgkin's lymphoma along a continuous step-by-step model of B-cell lymphomagenesis, where the intermediated mixed cryoglobulinemia[ncbi.nlm.nih.gov] Yellow discoloration in the skin and eyes (jaundice) Fluid accumulation in your abdomen (ascites) Spiderlike blood vessels on your skin Redness in the palms of the hands[mayoclinic.org] phosphatase (ALP).[qi.quintessenz.de]

  • Infectious Mononucleosis

    Arima, Mami Tamai, Satoshi Yamasaki, Hideki Nakamura, Hiroyuki Moriuchi and Atsushi Kawakami, An elderly patient with chronic active Epstein–Barr virus infection with mixed cryoglobulinemia[oadoi.org] skin.[hopkinsmedicine.org] discoloration of the skin and whites of the eyes due to abnormally high levels of bilirubin (bile pigmentation) in the bloodstream Once a person has had mononucleosis, the[hopkinsmedicine.org]

  • Autoimmune Hepatitis

    cryoglobulinemia is more common.[merckmanuals.com] discoloration of the skin and the whites of the eyes ( jaundice ).[labtestsonline.org] phosphatase – In 80-90% of patients; a sharp increase in the alkaline phosphatase values during the course of autoimmune disease may reflect the development of primary sclerosing[emedicine.com]

  • Liver Disease

    Keratoconjunctivitis (sicca syndrome), glomerulonephritis, skin disorders (for example, lichen planus, porphyria cutanea tarda), neuropathy, and immune dysfunction (for example, cryoglobulinemia[ssa.gov] Symptoms of liver diseases include weakness and fatigue, weight loss, nausea, vomiting, and yellow discoloration of the skin (jaundice).[medicinenet.com] […] bilirubin (without increase in alkaline phosphatase) (See web-based course on liver function test abnormalities .)[hiv.va.gov]

  • Hepatitis A

    Transverse myelitis Renal findings Acute tubular necrosis Interstitial nephritis Mesangial proliferative glomerulonephritis Nephrotic syndrome Other findings Cutaneous vasculitis Cryoglobulinemia[aafp.org] The most common symptoms are as follows: Nausea Vomiting Diarrhea, especially in children Low-grade fever Loss of appetite Rash Tiredness, fatigue Jaundice - A yellow discoloration[web.archive.org] Alkaline phosphatase activity also rises relatively late in the course of the infection, and tends to parallel serum bilirubin increases.[clinchem.org]

  • Hepatitis G

    Hepatitis C virus (HCV) infection is associated with type II cryoglobulinemia.[ncbi.nlm.nih.gov] Hepatitis may occur with limited or no symptoms, but often leads to yellow discoloration of the skin, mucus membranes, and conjunctivae, poor appetite and malaise.[disabled-world.com] There is also evidence for two-fold increases in the activity of alkaline phosphatase (AP) and γ-glutamyl transpeptidase (γ-GTP) in GBV-C positive patients[ 95 ].[dx.doi.org]

  • Hepatocellular Carcinoma

    For people with hepatitis C, the rash is usually a symptom of cryoglobulinemia.[webmd.com] The rare patient with a hepatic adenoma will also develop pain just below the right rib cage, vague discomfort, itching or yellowing discoloration of the skin.[hepatocellular.org] Rarely, hemoperitoneum in a cirrhotic patient may shine the light on HCC after a sudden increase in alkaline phosphatase and aspartate transaminase/alanine transaminase levels[docksci.com]

  • Hepatitis E

    Type II cryoglobulinemia with monoclonal immunoglobulin G (IgG) κ light chain was detected.[ncbi.nlm.nih.gov] Typical signs and symptoms of hepatitis include jaundice (yellow discoloration of the skin and sclera of the eyes, dark urine and pale stools), anorexia (loss of appetite)[hepfi.org] During acute infection, infected individuals may see a rise bilirubin (bile pigments) in the blood and urine, and a slight increase in alkaline phosphatase, an enzyme of the[ppdictionary.com]

Similar symptoms