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64 Possible Causes for Alkaline Phosphatase Increased, Hepatomegaly, Increased Echogenicity

  • Liver Cirrhosis

    Cardinal symptoms include fasting hypoglycemia, lactic acidosis and hepatomegaly as well as neutropenia.[] Findings that suggest the presence of cirrhosis include: Small, contracted liver Surface nodularity, increased echogenicity of liver Splenomegaly Ascites Collateral veins[] phosphatase (ALP).[]

  • Portal Cirrhosis

    The presence of this triad in a patient with unexplained hepatomegaly is indicative of portal cirrhosis.[] Parenchymal changes seen in patients with diffuse liver disease and cirrhosis include surface nodularity, increased echogenicity, coarsened echotexture, and a high caudate-to-right[] The liver becomes large, even huge (hepatomegaly). The normal liver weighs about 1,200 grams (2.6 lb).[]

  • Fatty Liver

    Ultrasound findings are those of hepatic steatosis, with increased echogenicity and coarsened echotexture of the liver (see also: grading of diffuse hepatic steatosis ) if[] Furthermore, these cases of hepatomegaly and fatty liver have been also in the context of concomitant extrahepatic side effects.[] Blood levels of alkaline phosphatase may become elevated in NAFLD. Sometimes ferritin level is elevated as well.[]

  • Acute Fatty Liver of Pregnancy

    USG abdomen revealed hepatomegaly with fatty changes grade 2-3, medical renal disease, and minimal ascites.[] The ultrasound findings were normal in 12 patients, an increasingly coarsened echo-pattern and increased echogenicity of the liver in 10 patients, and mild to moderate fatty[] The serum concentrations of transaminase enzymes, bilirubin, and alkaline phosphatase were increased, and a mild coagulopathy was present.[]

  • Hepatic Sarcoidosis

    Clinical presentation was with weight loss, hepatomegaly and abnormal liver function tests.[] […] homogeneous or heterogeneous echogenicity nodules are usually hypoechoic relative to the background liver 1 CT and MRI : in most patients the liver appears homogeneous 10[] His ESR (9mm) and Alkaline Phosphatase (104 IU) - though not his yGT - declined rapidly to normal.[]

  • Liver Disease

    CASE REPORT In 1979, CESD was first diagnosed in a 13-year-old female with marked hepatomegaly.[] Abdominal ultrasound 5 weeks after SIRT revealed a slightly increased echogenicity of the liver.[] […] bilirubin (without increase in alkaline phosphatase) (See web-based course on liver function test abnormalities .)[]

  • Liver Abscess

    CASE PRESENTATION: We report a case of a 63-year-old male with a history of anorexia for 3 weeks, fever for 4 days and examination findings of tender hepatomegaly with a liver[] An abdominal CT scan ( Fig. 1 ) revealed an increase in the size of the left lobe of the liver with a heterogeneous alteration of its echogenicity, but no clear image of mass[] Liver function tests showed a grade 1 increase in bilirubin and transaminases and a grade 2 increase in alkaline phosphatases and gammaglutamyltransferase.[]

  • Angiomyolipoma

    Examination revealed hepatomegaly with tenderness in the right upper quadrant.[] Echocardiography revealed right cardiac chambers with increased dimensions related to a large echogenic tumor with an inferior component within the inferior vena cava ( Figure[] Pregnancy increases the risk of rupture.[]

  • Primary Biliary Cirrhosis

    […] bile ducts affected only irregularly ( Hum Pathol 2002;33:983 ) 85% women, usually ages 40 - 60 Symptoms: insidious onset of pruritis, malaise, dark urine, light stools, hepatomegaly[] A bedside ultrasound of the right upper quadrant showed a liver measuring 15 cm with increased echogenicity, suggesting the presence of fatty infiltration but revealing no[] We had also observed in the other three groups of patients that the average of the values of γ-glutamyl transpeptidase and alkaline phosphatase increases with the increase[]

  • Secondary Amyloidosis

    Hepatomegaly, splenomegaly, and autonomic neuropathy frequently occur as the disease progresses; cardiomyopathy occurs rarely.[] Ultrasound examination revealed enlarged kidneys with increased echogenicity in all patients. All patients had a medical history of chronic or repeated infections.[] The median SAA concentration in these patients was 51 mg per liter, a finding that is consistent with increased production of alkaline phosphatase as an acute-phase reactant[]

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