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522 Possible Causes for Alkaline Phosphatase Increased, Hypercalcemia

  • Primary Hyperparathyroidism

    Hypercalcemia is found frequently in patients with cancer.[ncbi.nlm.nih.gov] Serum calcium is increased. Serum phosphorus may be decreased. Serum alkaline phosphatase may be increased. Bone x-ray may show bone reabsorption or fractures.[uclahealth.org] Laboratory analyses of blood samples typically reveal increased levels of PTH, hypercalcemia, hypophosphatemia and augmented alkaline phosphatase levels.[symptoma.com]

  • Sarcoidosis

    A blood analysis revealed hypercalcemia. Computed tomography revealed mediastinal and hilar lymph node hyperplasia.[ncbi.nlm.nih.gov] Phosphate and alkaline phosphatase may be increased. LFTs may show derangement. If calcium is elevated then 24-hour urinary collection may demonstrate hypercalciuria.[patient.info] The patient was started on aggressive intravenous fluid hydration and intravenous calcitonin, after which her altered mental status resolved and both kidney function and hypercalcemia[ncbi.nlm.nih.gov]

  • Multiple Myeloma

    Spontaneous respiration and gastrointestinal function were restored after the correction of hypercalcemia.[ncbi.nlm.nih.gov] Hepatic manifestations, observed in 30% of patients, usually consist of liver enlargement, accompanied by isolated increased serum alkaline phosphatase levels, without evidence[ojrd.biomedcentral.com] We report the case of a 25-year-old man with femoral Streptococcus pneumoniae pyomyositis as well as hypercalcemia, mild anemia, and elevated inflammatory markers; he subsequently[ncbi.nlm.nih.gov]

  • Vitamin D

    Prednisolone treatment improved the hypercalcemia and decreased the levels of 1,25(OH)2D and IL-6. We first reported a case of vitamin D-mediated hypercalcemia in MCD.[ncbi.nlm.nih.gov] Hypercalcemia is caused by many different conditions and may lead to severe complications.[ncbi.nlm.nih.gov] Idiopathic infantile hypercalcemia is caused by mutations of the CYP24A1 gene, which regulates vitamin D activity. Classically infants present with hypercalcemia.[ncbi.nlm.nih.gov]

  • Graves Disease

    The possibility of their coexistence should therefore be taken into consideration in cases of hypercalcemia.[ncbi.nlm.nih.gov] Both of primary hyperparathyroidism and Graves' disease can contribute and accelerate hypercalcemia, resulting in a state of crisis.[ncbi.nlm.nih.gov]

  • Osteitis Deformans

    The agency did not specify a time frame for the short-term use of calcitonin for treating hypercalcemia caused by cancer.[en.wikipedia.org] The amount of blood serum alkaline phosphatase increased. A diseased bone increased demand for oxygen and nutrients causes increased load on the heart.[medicalformat.com] Plasma alkaline phosphatase concentration is increased.[books.google.com]

  • Hepatic Sarcoidosis

    We report a case of early recurrence of sarcoidosis in the liver allograft diagnosed on biopsy in a patient who presented with severe hypercalcemia, kidney dysfunction, and[ncbi.nlm.nih.gov] His ESR (9mm) and Alkaline Phosphatase (104 IU) - though not his yGT - declined rapidly to normal.[jpma.org.pk] However a moderately increased Serum Angiotensin Converting Enzyme and hypercalcemia were present.[minervamedica.it]

  • Total Parenteral Nutrition

    We report a patient with long-term TPN, who demonstrated hypercalciuria, hypercalcemia and growth retardation.[ncbi.nlm.nih.gov] Under this treatment, serum total bilirubin was significantly decreased at 3 months, total cholesterol was significantly decreased at 2 months, and alkaline phosphatase (ALP[ncbi.nlm.nih.gov] .  Fluid overload  Hypo/hypernatremia  Hypercalcemia  Hypo/hyperkalemia Infection :  Catheter related sepsis is most common life threatening complication  Causes: staph[slideshare.net]

  • Hepatocellular Carcinoma

    Occasionally, systemic metabolic complications, including hypoglycemia, erythrocytosis, hypercalcemia, and hyperlipidemia, occur.[merckmanuals.com] […] strong link to smoking more common in men Presentation central (hilar) cavitating lesion can ectopically secrete PTH-related protein (PTHrP) results in parathyroid-like hypercalcemia[medbullets.com]

  • Fanconi Syndrome

    A 77-year-old female with renal dysfunction, hypercalcemia, and hypercalciuria was presented.[ncbi.nlm.nih.gov] phosphatase Greatly elevated alkaline phosphatase High serum alkaline phosphatase Increased alkaline phosphatase Increased serum alkaline phosphatase Last updated: 2/27/2017[rarediseases.info.nih.gov] All recruited patients had hypophosphataemia, increased urinary phosphate excretion and elevated alkaline phosphatase.[ncbi.nlm.nih.gov]

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