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129 Possible Causes for Alkaline Phosphatase Increased, Hypervitaminosis D

  • Vitamin D

    D toxicity.[ncbi.nlm.nih.gov] Serum phosphate usually decreases, and serum alkaline phosphatase usually increases. Serum PTH may be normal or elevated.[merck.com] […] of serum alkaline phosphatase activity; circulating concentrations of 1,25(OH) 2 D are low or undetectable. 4 Before the availability of 1α-hydroxylated vitamin D metabolites[doi.org]

  • Osteoporosis

    D toxicity Future research References Chapter 9.[fao.org] Increased rates of osteoclastic bone resorption, measured by the level of collagen breakdown products, as well as increased bone formation, measured by bone-specific alkaline[dx.doi.org] D toxicity, autoimmune sarcoidosis or excessive bone breakdown related to “silent” diseases like diabetes or thyroid disorders.[betterbones.com]

  • Vitamin D Deficiency

    Vitamin D toxicity usually results from taking supplements in excess.[en.wikipedia.org] Juvenile Paget's disease (JPD) is a rare heritable osteopathy characterized biochemically by markedly increased serum alkaline phosphatase (ALP) activity emanating from generalized[ncbi.nlm.nih.gov] Serum phosphate usually decreases, and serum alkaline phosphatase usually increases. Serum PTH may be normal or elevated.[merck.com]

  • Osteomalacia

    D Increased Increased Normal Decreased Treatment Medical treatment is directed against the underlying cause for example vitamin D supplemention indication in patients with[step2.medbullets.com] Renal dysfunction, hypophosphatemia and increased levels of bone alkaline phosphatase were found.[ncbi.nlm.nih.gov] Rickets and hypervitaminosis D. In: Kliegman RM, Stanton BF, St. Geme JW, Schor NF, eds. Nelson Textbook of Pediatrics . 20th ed.[mountsinai.org]

  • Nephrocalcinosis

    D Milk-alkali syndrome Williams syndrome Oxalosis ( /- completely opaque kidneys; younger age) Tuberculosis Cortical Nephrocalcinosis Acute cortical necrosis (hypotensive[radipedia.com] […] in alkaline phosphatase.[ncbi.nlm.nih.gov] Pathology Causes include 1,2 : medulla hyperparathyroidism medullary sponge kidney renal tubular acidosis (type 1) hypervitaminosis D milk-alkali syndrome sarcoidosis hyperthyroidism[radiopaedia.org]

  • Osteitis Fibrosa Cystica

    Do you know why ALP is normal in hypervitaminosis D?[forums.studentdoctor.net] […] in alkaline phosphatase to 486 units/l.[ncbi.nlm.nih.gov] D), Paget s disease, myelofibrosis, mastocytosis, aplastic anemia.[gamma.wustl.edu]

  • Familial Hypophosphatemia

    D Increased Increased Normal Decreased Treatment Medical treatment is directed against the underlying cause for example vitamin D supplemention indication in patients with[medbullets.com] […] serum alkaline phosphatase level Tetany Calcium, magnesium, vitamin D malabsorption Hypocalcemia, hypophosphatemia, increased serum alkaline phosphatase level, hypomagnesemia[aafp.org] If the ratio exceeds 0.25, discontinue the 1,25(OH) 2 D for a few days. 4 Complications Hypervitaminosis D occurs secondary to high doses of fat-soluble vitamin D and infrequent[consultant360.com]

  • Vitamin D Toxicity

    Abstract Vitamin D toxicity also known as hypervitaminosis D was previously believed to be rare.[ncbi.nlm.nih.gov] phosphatase ( 26 ).[fao.org] […] usually accompanies them, demanding that an alternative explanation for the mechanism of vitamin D toxicity be developed.[ncbi.nlm.nih.gov]

  • Sarcoidosis

    Possible causes entertained were malignancy, hyperparathyroidism, hypervitaminosis D, and granulomatous diseases.[ncbi.nlm.nih.gov] Phosphate and alkaline phosphatase may be increased. LFTs may show derangement. If calcium is elevated then 24-hour urinary collection may demonstrate hypercalciuria.[patient.info] […] hepatic enzymes or alkaline phosphatase .[en.wikipedia.org]

  • Hereditary Hypophosphatemic Rickets with Hypercalciuria

    Rickets and hypervitaminosis D. In: Kliegman RM, Behrman RE, Jenson HB, Stanton BF, ed. Nelson Textbook of Pediatrics.[scielo.mec.pt] When there is a deficiency of vitamin D, the amount of phosphorus and calcium in the blood decreases, the activity of alkaline phosphatase increases, the amount of citrates[encyclopedia2.thefreedictionary.com] In osteoblasts isolated from a HHRH patient, basal alkaline phosphatase (ALP) activities and osteocalcin syntheses by a physiological concentration of 1,25(OH)(2)D(3) were[ncbi.nlm.nih.gov]

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