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90 Possible Causes for Alkaline Phosphatase Increased, Hypervitaminosis D

  • Vitamin D Deficiency

    Vitamin D toxicity usually results from taking supplements in excess.[en.wikipedia.org] Juvenile Paget's disease (JPD) is a rare heritable osteopathy characterized biochemically by markedly increased serum alkaline phosphatase (ALP) activity emanating from generalized[ncbi.nlm.nih.gov] Laboratory test showed severe hypocalcemia, elevated alkaline phosphatase, normal serum phosphorous, decreased 25(OH) cholecalciferol, increased intact parathyroid hormone[ncbi.nlm.nih.gov]

  • Osteitis Fibrosa Cystica

    Do you know why ALP is normal in hypervitaminosis D?[forums.studentdoctor.net] […] in alkaline phosphatase to 486 units/l.[ncbi.nlm.nih.gov] D), Paget s disease, myelofibrosis, mastocytosis, aplastic anemia.[gamma.wustl.edu]

  • Vitamin D

    D toxicity.[ncbi.nlm.nih.gov] Serum phosphate usually decreases, and serum alkaline phosphatase usually increases. Serum PTH may be normal or elevated.[merck.com] […] of serum alkaline phosphatase activity; circulating concentrations of 1,25(OH) 2 D are low or undetectable. 4 Before the availability of 1α-hydroxylated vitamin D metabolites[doi.org]

  • Sarcoidosis

    Possible causes entertained were malignancy, hyperparathyroidism, hypervitaminosis D, and granulomatous diseases.[ncbi.nlm.nih.gov] Phosphate and alkaline phosphatase may be increased. LFTs may show derangement. If calcium is elevated then 24-hour urinary collection may demonstrate hypercalciuria.[patient.info] phosphatase Hypercalcemia/hypercalciuria/nephrolithiasis Increased serum calcium with no other cause Increased urine calcium Nephrolithiasis, no stone analysis Nephrolithiasis[doi.org]

  • Nephrocalcinosis

    D Milk-alkali syndrome Williams syndrome Oxalosis ( /- completely opaque kidneys; younger age) Tuberculosis Cortical Nephrocalcinosis Acute cortical necrosis (hypotensive[radipedia.com] […] in alkaline phosphatase.[ncbi.nlm.nih.gov] Pathology Causes include 1,2 : medulla hyperparathyroidism medullary sponge kidney renal tubular acidosis (type 1) hypervitaminosis D milk-alkali syndrome sarcoidosis hyperthyroidism[radiopaedia.org]

  • Hepatic Sarcoidosis

    Elevated serum calcium Hypervitaminosis-D is associated with hypercalcemia.[chronicillnessrecovery.org] His ESR (9mm) and Alkaline Phosphatase (104 IU) - though not his yGT - declined rapidly to normal.[jpma.org.pk] The lab tests showed an increase of the liver enzymes: AST 95 U/L (10–37), ALT 130 U/L (10–37), gamma-GT 317 U/L (10–49), alkaline phosphatase 561 U/L (30–120), hypergammaglobulinemia[reumatologiaclinica.org]

  • Osteomalacia

    D Increased Increased Normal Decreased Treatment Medical treatment is directed against the underlying cause for example vitamin D supplemention indication in patients with[step2.medbullets.com] Renal dysfunction, hypophosphatemia and increased levels of bone alkaline phosphatase were found.[ncbi.nlm.nih.gov] Rickets and hypervitaminosis D. In: Kliegman RM, Stanton BF, St. Geme JW, Schor NF, eds. Nelson Textbook of Pediatrics. 20th ed.[mountsinai.org]

  • Rickets

    Rickets and hypervitaminosis D. In: Kliegman RM, Stanton BF, St. Geme JW, Schor NF, eds. Nelson Textbook of Pediatrics. 20th ed.[nlm.nih.gov] Biochemical test showed obviously increased alkaline phosphatase (ALP) and parathyroid hormone (PTH), mild hypocalcemia and hypophosphatemia.[ncbi.nlm.nih.gov] Rickets and hypervitaminosis D. In: Kliegman RM, Stanton BF, St. Geme JW, Schor NF, eds. Nelson Textbook of Pediatrics . 20th ed.[medlineplus.gov]

  • Extrahepatic Cholestasis

    Other causes of low ALP that have been reported in the medical literature include: Hypophosphatasia Hypoparathyroidism Zinc deficiency Vitamin D toxicity Collection of blood[clinlabnavigator.com] […] of GGT as a marker for CEHC is similar to that of alkaline phosphatase.[ncbi.nlm.nih.gov] Early biochemical markers in often asymptomatic patients include increases in serum alkaline phosphatase (AP) and γ-glutamyltranspeptidase (γGT) followed by conjugated hyperbilirubinemia[easl.eu]

  • Familial Hypophosphatemia

    D Increased Increased Normal Decreased Treatment Medical treatment is directed against the underlying cause for example vitamin D supplemention indication in patients with[medbullets.com] alkaline phosphatase levels is a typical laboratory profile in patients with XLH rickets.[consultant360.com] Increase in plasma phosphate and decrease in alkaline phosphatase concentrations, healing of rickets, and improvement of growth rate occur.[msdmanuals.com]

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