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312 Possible Causes for Alkaline Phosphatase Increased, Interstitial Pneumonitis

  • Infectious Mononucleosis

    In patients with AIDS, Epstein-Barr virus is associated with hairy leukoplakia, leiomyosarcoma, CNS lymphoma, and lymphoid interstitial pneumonitis in children.[emedicine.com] However, it may occasionally cause a syndrome of fever, interstitial pneumonitis, pancytopenia, and uveitis (ie, chronic active EBV).[merck.com]

  • Sepsis

    Three days after initiation of ECMO, the patient developed jaundice, with increase of bilirubin, Gamma-glutamyltransferase and Alkaline phosphatase, without elevation of alanine[ncbi.nlm.nih.gov] Acute interstitial pneumonia. A clinicopathologic, ultrastructural, and cell kinetic study. Am J Surg Pathol. 1986 Apr. 10(4):256-67. [Medline].[medscape.com] Although ECMO was stopped, bilirubin serum levels were increasing, reaching the peak of 18.41 mg/dL of total and 15.67 mg/dL of direct bilirubin.[ncbi.nlm.nih.gov]

  • Congestive Heart Failure

    Thereafter, video-assisted thoracoscopic surgery was performed, resulting in a diagnosis of cellular non-specific interstitial pneumonia (c-NSIP).[ncbi.nlm.nih.gov]

  • Bone Metastasis

    Laboratory investigations are of limited value, but will often demonstrate increased serum calcium and alkaline phosphatase 1,3.[radiopaedia.org] She had a past history of rheumatoid arthritis, scleroderma, interstitial pneumonia, angina pectoris (with coronary artery bypass surgery) and arrhythmia (with pacemaker implantation[ncbi.nlm.nih.gov] Laboratory investigations are of limited value, but will often demonstrate increased serum calcium and alkaline phosphatase 1,3 .[radiopaedia.org]

  • Sarcoidosis

    Phosphate and alkaline phosphatase may be increased. LFTs may show derangement. If calcium is elevated then 24-hour urinary collection may demonstrate hypercalciuria.[patient.info] The pulmonary sarcoidosis did not show any deterioration despite the frequent use of amrubicin, which is known to be a cause of interstitial pneumonia.[ncbi.nlm.nih.gov] phosphatase Hypercalcemia/hypercalciuria/nephrolithiasis Increased serum calcium with no other cause Increased urine calcium Nephrolithiasis, no stone analysis Nephrolithiasis[doi.org]

  • Viral Hepatitis

    Hepatosplenomegaly and laboratory evidence of mild to moderate hepatic dysfunction are the predominant features, with increased aminotransferases and alkaline phosphatase[doi.org] Chronic infection may be inapparent. viral hepatitis see duck hepatitis. viral interstitial pneumonia bovine syncytial virus, a common cause of interstitial pneumonia in all[medical-dictionary.thefreedictionary.com] Alkaline phosphatase (ALP) – an enzyme related to the bile ducts but also found in other tissues throughout the body.[labtestsonline.org]

  • Multiple Myeloma

    Hepatic manifestations, observed in 30% of patients, usually consist of liver enlargement, accompanied by isolated increased serum alkaline phosphatase levels, without evidence[ojrd.biomedcentral.com] Thalidomide-induced interstitial pneumonitis. J Clin Oncol. 2005; 23 :2425–6. [ PubMed ] [ Google Scholar ] 36. Kyle RA, Rajkumar SV. Multiple myeloma.[doi.org] Pulmonary Toxicity Acute Respiratory Distress Syndrome (ARDS), acute respiratory failure, and acute diffuse infiltrative pulmonary disease such as pneumonitis and interstitial[investors.amgen.com]

  • Angiomyolipoma

    Acute interstitial pneumonitis is a rare but serious and potentially life-threatening side-effect of sirolimus.[academic.oup.com] pneumonia, delayed wound healing, and infection. 30-34 Montalbano et al. reported that sirolimus had to be discontinued because of side effects in 24% of liver-transplant[nejm.org] […] multiforme. 29 Reported adverse effects of sirolimus include leukopenia, thrombocytopenia, hypertriglyceridemia, hypercholesterolemia, aphthous ulcers, edema, joint pain, interstitial[nejm.org]

  • Primary Biliary Cirrhosis

    We had also observed in the other three groups of patients that the average of the values of γ-glutamyl transpeptidase and alkaline phosphatase increases with the increase[ncbi.nlm.nih.gov] A patient with primary Sjögren's syndrome complicated with primary biliary cirrhosis and lymphocytic interstitial pneumonia is presented.[ncbi.nlm.nih.gov] alkaline phosphatase levels results in an improvement of cholestasis as compared to placebo, with a parallel decrease of aminotransferases and immunoglobulin M, as well as[ncbi.nlm.nih.gov]

  • Massive Hepatic Necrosis

    […] elevation of serum alkaline phosphatase and bilirubin.[annals.org] Diffuse interstitial pneumonia. 5. Atelectasis of lower lobes. 6. Acute passive congestion of viscera. 7. Massive acute central necrosis of liver cells. 8. Ascites. 9.[nap.edu] Hepatic involvement is a common finding in cytomegalovirus mononucleosis as manifested by mild hepatomegaly, consistent increases in serum transaminase activity, and variable[annals.org]

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