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430 Possible Causes for Alkaline Phosphatase Increased, Iron Increased

  • Chronic Alcoholism

    Coexisting iron accumulation or chronic hepatitis C increases risk of hepatocellular carcinoma.[] Other factors that may trigger type 1 PCT include oestrogen, iron and viral infections (especially hepatitis C).[] A diet high in unsaturated fat increases susceptibility, as does obesity.[]

  • Hemochromatosis

    Recent studies have shown an increased concentration of redox-active iron in plasma in patients with increased transferrin saturation.[] DISCUSSION: In the placenta of NH, increases in expressions of TFR1, transferrin, and ferritin of which those of TFR1 were especially marked, reflect increased iron influx[] BACKGROUND: Hereditary hemochromatosis is a disorder of iron metabolism characterized by increased iron absorption.HFE gene mutations C282Y and H63D are responsible for the[]

  • Liver Failure

    Screening and detection tests include: Alanine aminotransferase (ALT) – an enzyme found mainly in the liver; best test to detect hepatitis Alkaline phosphatase (ALP) – an[] Serum ferritin levels are frequently elevated, while iron and iron-binding capacity are normal ( 42 , 130 ).[] […] in serum IgG, and normal or only slightly elevated alkaline phosphatase.[]

  • Portal Cirrhosis

    Laennec's cirrhosis, also known as portal cirrhosis, alcoholic cirrhosis, fatty cirrhosis, or atrophic cirrhosis, [1] is named after René Laennec, [2] a French physician and the inventor of the stethoscope. It is a disease of the liver in which the normal lobular architecture is lost, with fibrosis (scarring) and later[…][]

  • Viral Hepatitis

    Hepatosplenomegaly and laboratory evidence of mild to moderate hepatic dysfunction are the predominant features, with increased aminotransferases and alkaline phosphatase[] Alkaline phosphatase (ALP) – an enzyme related to the bile ducts but also found in other tissues throughout the body.[] The ALP test is often increased when bile ducts are blocked but may also be increased with bone disorders.[]

  • Vitamin D Deficiency

    Juvenile Paget's disease (JPD) is a rare heritable osteopathy characterized biochemically by markedly increased serum alkaline phosphatase (ALP) activity emanating from generalized[] Low PTH is correlated with increased cardiac iron.[] Laboratory test showed severe hypocalcemia, elevated alkaline phosphatase, normal serum phosphorous, decreased 25(OH) cholecalciferol, increased intact parathyroid hormone[]

  • Pregnancy

    There is no evidence that iron supplementation increases placental malaria. For some outcomes heterogeneity was higher than 50%.[] Iron requirements increase notably during the second half of pregnancy because of the expansion of the red blood cell mass and the transfer of increasing amounts of iron to[] It should also be noted that vitamin C increases iron absorption, meaning that iron-rich foods (or an iron-fortified supplement) is best taken with orange juice or tomato[]

  • Third Trimester Pregnancy

    This trimester still calls for higher levels of iron and protein.[] During the last trimester of pregnancy it becomes even more important as your body will increase the supply of blood to the placenta.[] In fact the amount of blood increases by 50%. No wonder so many women experience low iron counts, also those eating an omnivorous diet rich in meat.[]

  • Liver Cirrhosis

    phosphatase (ALP).[] Iron absorption can be increased if iron stores are depleted (usually through blood loss), and in genetically normal people absorption decreases with iron overload 1, 2 (usually[] […] bilirubin (without increase in alkaline phosphatase) (See web-based course on liver function test abnormalities .)[]

  • Sepsis

    Three days after initiation of ECMO, the patient developed jaundice, with increase of bilirubin, Gamma-glutamyltransferase and Alkaline phosphatase, without elevation of alanine[] Iron overload states are known to increase patient susceptibility to infections caused by lower virulence bacteria lacking sophisticated iron metabolism pathways, for example[] The literature concerning the role of iron in microbe-host interaction and the increased susceptibility to infection of patients with hemochromatosis is reviewed.[]

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