Create issue ticket

58 Possible Causes for Alkaline Phosphatase Increased, Monoclonal Gammopathy of Undetermined Significance

  • Multiple Myeloma

    Summary Monoclonal gammopathy of undetermined significance (MGUS) is one of the most common premalignant disorders.[doi.org] Monoclonal gammopathy of undetermined significance (MGUS) is a premalignant plasma-cell proliferative disorder associated with a life-long risk of progression to multiple[ncbi.nlm.nih.gov] Monoclonal gammopathy of undetermined significance (MGUS) is one of the most common premalignant disorders.[ncbi.nlm.nih.gov]

  • Systemic Amyloidosis

    Prognostic significance of whole-body MRI in patients with monoclonal gammopathy of undetermined significance.[ncbi.nlm.nih.gov] […] of NT-proBNP in the absence of primary heart disease, presence of hepatomegaly or increase of alkaline phosphatase without an imaging abnormality, peripheral and/or autonomic[doi.org] […] of vital capacity and forced expiratory volume); and 1 patient, with liver involvement, had normalization of alkaline phosphatase (from 451 to 178 U/L; reference, 279 U/L[doi.org]

  • Fanconi Syndrome

    Further exploration revealed monoclonal gammopathy of undetermined significance (MGUS) excreting urinary Bence Jones protein (kappa light chain).[doi.org] phosphatase Greatly elevated alkaline phosphatase High serum alkaline phosphatase Increased alkaline phosphatase Increased serum alkaline phosphatase Last updated: 2/27/2017[rarediseases.info.nih.gov] RESULTS: All recruited patients had hypophosphataemia, increased urinary phosphate excretion and elevated alkaline phosphatase.[ncbi.nlm.nih.gov]

  • Amyloidosis

    OBJECTIVE: To identify the prevalence of monoclonal gammopathy of undetermined significance (MGUS) in patients with transthyretin (ATTR) amyloidosis.[ncbi.nlm.nih.gov] Hepatomegaly or increased alkaline phosphatase** 4. Monoclonal gammopathy with a. Autonomic or sensory neuropathy b. Unexplained fatigue c. Edema d.[doi.org] More importantly, patients being monitored for smoldering multiple myeloma and a monoclonal gammopathy of undetermined significance (MGUS) are at risk for developing AL amyloidosis[ncbi.nlm.nih.gov]

  • Secondary Amyloidosis

    Monoclonal gammopathy of undetermined significance, Waldenstrom macroglobulinemia, AL amyloidosis, and related plasma cell disorders: diagnosis and treatment.[doi.org] The median SAA concentration in these patients was 51 mg per liter, a finding that is consistent with increased production of alkaline phosphatase as an acute-phase reactant[doi.org]

  • Hepatocellular Carcinoma

    […] of undetermined significance and lymphomas with plasmacytoid differentiation."[e-immunohistochemistry.info] […] in gamma-glutamyl transpeptidase/alkaline phosphatase in non-cirrhotic patients( 45, 52 ).[doi.org] "Expression of CD56/neural cell adhesion molecule correlates with the presence of lytic bone lesions in multiple myeloma and distinguishes myeloma from monoclonal gammopathy[e-immunohistochemistry.info]

  • Osteogenesis Imperfecta

    MGUS: 2010: MGUS, Consensus Statement PMID 20507313 -- "Monoclonal gammopathy of undetermined significance: a consensus statement."[en.wikibooks.org] Blood calcium, phosphate, albumin, fasting urinary calcium/creatinine ratio, total serum alkaline phosphatase, and bone alkaline phosphatase were obtained at baseline and[ncbi.nlm.nih.gov] Levels of biochemical markers of bone metabolism generally were within the reference range, but serum alkaline phosphatase and urinary collagen type I N-telopeptide excretion[ncbi.nlm.nih.gov]

  • Primary Amyloidosis

    Prognostic significance of whole-body MRI in patients with monoclonal gammopathy of undetermined significance.[ncbi.nlm.nih.gov] Functional liver tests evidenced a high level of alkaline phosphatase and serum gamma-glutamyl transpeptidase with mild increase of bilirubin level.[ncbi.nlm.nih.gov] […] of vital capacity and forced expiratory volume); and 1 patient, with liver involvement, had normalization of alkaline phosphatase (from 451 to 178 U/L; reference, 279 U/L[doi.org]

  • Systemic Mastocytosis

    Non-IgM monoclonal gammopathy of undetermined significance b)Plasma cell myeloma c)Plasma cell myeloma variants d)Plasmacytoma e)Monoclonal immunoglobulin deposition diseases[chugaiigaku.jp] In multivariate analysis of all patients, an increased spleen volume 450 ml (hazard ratio (HR), 5.2; 95% confidence interval (CI), (2.1-13.0); P 0.003) and an elevated alkaline[ncbi.nlm.nih.gov] Preoperative laboratory investigations were normal, except for moderate anemia (hemoglobin 99 g/L), increased alkaline phosphatase (196 U/L, normal 36-108 U/L), and decreased[journals.lww.com]

  • Acquired Von Willebrand Syndrome

    Here we present a case in which a patient presented with profound epistaxis and was found to have AVWS in the setting of monoclonal gammopathy of undetermined significance[ncbi.nlm.nih.gov] The leucocyte alkaline phosphatase (LAP) score was low 14 (normal score 10-100).[omicsonline.org] We report herein the case of a 69-year-old Japanese man with acquired von Willebrand syndrome associated with monoclonal gammopathy of undetermined significance who developed[ncbi.nlm.nih.gov]

Further symptoms

Similar symptoms