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706 Possible Causes for Alkaline Phosphatase Increased, Poor Outcome

  • Vitamin D Deficiency

    The aim of this trial is to determine if vitamin D deficiency is a modifiable risk factor for poor outcome after THR/TKR.[ncbi.nlm.nih.gov] Juvenile Paget's disease (JPD) is a rare heritable osteopathy characterized biochemically by markedly increased serum alkaline phosphatase (ALP) activity emanating from generalized[ncbi.nlm.nih.gov] Laboratory test showed severe hypocalcemia, elevated alkaline phosphatase, normal serum phosphorous, decreased 25(OH) cholecalciferol, increased intact parathyroid hormone[ncbi.nlm.nih.gov]

  • Hepatosplenic Lymphoma

    outcome.[bloodjournal.org] Patients with post-transplant HSTL exhibit an especially poor outcome. Standard treatment has yet to be established.[ncbi.nlm.nih.gov] Liver test results were essentially normal, with slightly elevated levels of serum aspartate aminotransferase (ASAT), alanine aminotransferase (ALAT), or alkaline phosphatase[bloodjournal.org]

  • Secondary Sclerosing Cholangitis

    Sclerosing cholangitis in critically ill patients, however, is associated with rapid disease progression and poor outcome.[en.wikipedia.org] Laboratory tests Increased serum alkaline phosphatase, transaminase, bilirubin and IgM. Mitochondrial antibodies: rarely present.[meddean.luc.edu] In conclusion, SSC-CIP following major burn injury is a rapidly progressive disease with a poor outcome. Liver cirrhosis developed rapidly.[ncbi.nlm.nih.gov]

  • Sepsis

    Only surgical removal of the focus of infection and early onset of antibiotic therapy can prevent a very poor outcome.[ncbi.nlm.nih.gov] Three days after initiation of ECMO, the patient developed jaundice, with increase of bilirubin, Gamma-glutamyltransferase and Alkaline phosphatase, without elevation of alanine[ncbi.nlm.nih.gov] Interestingly, although clinical course and laboratory data suggested poor outcome, serial LiMAx test revealed improvement of the enzymatic liver function at this time point[ncbi.nlm.nih.gov]

  • Fracture

    Considering the notoriously poor outcomes, the importance of early recognition and accurate treatment should be emphasized repeatedly in similar lesions.[ncbi.nlm.nih.gov] Univariate analysis failed to find any factor that was significantly associated with a fair or poor outcome.[ncbi.nlm.nih.gov] OUTCOMES: Poor reduction of Milch type I LCFs resulted in incongruity of the articular surface and poor cosmetic results in two patients.[ncbi.nlm.nih.gov]

  • Pregnancy

    Denied pregnancies have a statistically significant worse outcome compared with a normal group; at least some of these poor outcomes are potentially avoidable.[doi.org] PURPOSE: The aim of the present study was to review current literature about risk factors for poor pregnancy outcome.[ncbi.nlm.nih.gov] Although there are no studies linking SDB to poor fetal outcomes, fetal well-being remains paramount throughout the course of pregnancy. Copyright 2018 Elsevier Inc.[ncbi.nlm.nih.gov]

  • Acute Liver Failure

    outcome of the disease.[ncbi.nlm.nih.gov] phosphatase and renal function biomarkers.[ncbi.nlm.nih.gov] Laboratory tests showed bilirubin of 13.2 mg/dL and marked elevations of serum ALT (1501 U/L) and AST (2800 U/L), with minimal increase in alkaline phosphatase (287 U/L).[livertox.nih.gov]

  • Liver Metastasis

    BACKGROUND: Liver metastasis is common in patients with colorectal cancer (CRC), and is correlated with poor outcome.[ncbi.nlm.nih.gov] Alkaline phosphatase, gamma-glutamyl transpeptidase, and sometimes LDH typically increase earlier or to a greater degree than do other test results; aminotransferase levels[msdmanuals.com] BACKGROUND: Recent studies have revealed that liver metastasis is associated with poor outcomes after treatment using immune checkpoint inhibitors, although the cause remains[ncbi.nlm.nih.gov]

  • Autoimmune Hepatitis

    Independent predictors of poor liver-related outcomes were incomplete normalization of ALT at 6 months (P 0.01), serum albumin 36 g/L (P 0.01), and age at presentation of[ncbi.nlm.nih.gov] phosphatase – In 80-90% of patients; a sharp increase in the alkaline phosphatase values during the course of autoimmune disease may reflect the development of primary sclerosing[emedicine.com] Autoimmune, Cholestatic and Biliary Disease Predictors of poor outcome in patients w ith autoimmune hepatitis: A population‐based study † ‡ Department of Gastroenterology,[doi.org]

  • Gallbladder Carcinoma

    Gallbladder carcinoid has a poor outcome, requires aggressive treatment, and should be considered as one of the rare but possible gallbladder lesions.[ncbi.nlm.nih.gov] Increased alkaline phosphatase and bilirubin levels are found in cases of advanced gallbladder cancer.[clinicaladvisor.com] BACKGROUND/AIM: Gallbladder carcinoma (GBCA) has extremely poor outcomes.[ncbi.nlm.nih.gov]

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