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1,214 Possible Causes for Alkaline Phosphatase Increased, Proximal Interphalangeal Joint Space Narrowed

  • Hemochromatosis

    Involvement of proximal interphalangeal joints, radiographic joint space narrowing and cartilage destruction is often evident in hemochromatosis.[clinicaladvisor.com] The second and third metacarpophalangeal joints are usually the first to be affected.[clinicaladvisor.com]

  • Primary Hyperparathyroidism

    Review Topic QID: 106788 1 Joint space narrowing at the proximal and distal interphalangeal joints 2 Osteoid matrix accumulation around bony trabeculae 3 Subperiosteal cortical[medbullets.com] Serum calcium is increased. Serum phosphorus may be decreased. Serum alkaline phosphatase may be increased. Bone x-ray may show bone reabsorption or fractures.[uclahealth.org] Laboratory analyses of blood samples typically reveal increased levels of PTH, hypercalcemia, hypophosphatemia and augmented alkaline phosphatase levels.[symptoma.com]

  • Secondary Hyperparathyroidism

    Review Topic QID: 106788 1 Joint space narrowing at the proximal and distal interphalangeal joints 2 Osteoid matrix accumulation around bony trabeculae 3 Subperiosteal cortical[medbullets.com] phosphatase) and fracture risk.6 In DOPPS I and II, risks of new fracture were 42% and 67% in patients with mildly and markedly increased alkaline phosphatase levels, respectively[ajmc.com] The increased preoperative level of the alkaline phosphatase and parathormone, along with the large dimension of the parathyroids and patient's age, could be regarded as predictive[cyberleninka.org]

  • Vitamin D Deficiency

    Juvenile Paget's disease (JPD) is a rare heritable osteopathy characterized biochemically by markedly increased serum alkaline phosphatase (ALP) activity emanating from generalized[ncbi.nlm.nih.gov] Laboratory test showed severe hypocalcemia, elevated alkaline phosphatase, normal serum phosphorous, decreased 25(OH) cholecalciferol, increased intact parathyroid hormone[ncbi.nlm.nih.gov] Serum phosphate usually decreases, and serum alkaline phosphatase usually increases. Serum PTH may be normal or elevated.[merckmanuals.com]

    Missing: Proximal Interphalangeal Joint Space Narrowed
  • Menopause

    The serum levels of calcium, osteocalcin, and alkaline phosphatase and osteoblast density in the tibia were increased, but the density of osteoclast was decreased in OVX rats[ncbi.nlm.nih.gov]

    Missing: Proximal Interphalangeal Joint Space Narrowed
  • Cholelithiasis

    Patients with increased CBD dilatation more than 5 mm showed statistically significant increases in alkaline phosphatase and gamma-glutamyltransferase.[ncbi.nlm.nih.gov] […] in serum bilirubin concentration, alkaline phosphatase activity, or aspartate transaminase activity.[link.springer.com] CONCLUSIONS: The incidence of cholelithiasis was not increased due to subtotal gastrectomy without vagotomy, but the incidence was higher after Billoth-II compared to Billoth-I[ncbi.nlm.nih.gov]

    Missing: Proximal Interphalangeal Joint Space Narrowed
  • Fracture

    Ann Anat. 2018 Mar;216:120-124. doi: 10.1016/j.aanat.2017.12.005. Epub 2018 Jan 1. Author information 1 Studio Fonzar, Strada dei Tigli, 54, 33030 Campoformido, UD, Italy. Electronic address: federica.fonzar@gmail.com. 2 Department of Stomatology, Universitat de València (Spain) Clínica Odontológica, Calle Gascó Oliag, 1, 46010[…][ncbi.nlm.nih.gov]

    Missing: Proximal Interphalangeal Joint Space Narrowed
  • Pregnancy

    Pregnancy in patients with end-stage renal disease is rare, with a paucity of management guidelines in the literature. Various hemodialysis (HD) and peritoneal dialysis (PD) protocols have been used to successfully manage pregnancy in this population; however, there is a growing body of evidence that the best[…][ncbi.nlm.nih.gov]

    Missing: Proximal Interphalangeal Joint Space Narrowed
  • Third Trimester Pregnancy

    The concomitant phenomenon of a third trimester pregnancy with a significant degree of pelvic organ prolapse is extremely rare. We report on a patient with pelvic organ prolapse complicating third trimester pregnancy treated by concomitant cesarean hysterectomy and abdominal sacrocolpopexy. A 30-year-old woman,[…][ncbi.nlm.nih.gov]

    Missing: Proximal Interphalangeal Joint Space Narrowed
  • Chronic Alcoholism

    The concept of "structural plasticity" has emerged as a potential mechanism in neurodegenerative and psychiatric diseases such as drug abuse, depression, and dementia. Chronic alcoholism is a progressive neurodegenerative disease while the person continues to abuse alcohol, though clinical and imaging studies show[…][ncbi.nlm.nih.gov]

    Missing: Proximal Interphalangeal Joint Space Narrowed

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