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87 Possible Causes for Alkalosis, Hyperreninemia, Muscle Weakness

  • Bartter's Disease

    Clinical findings Proximal muscle weakness, failure to thrive, short stature, convulsions, tetany, cramps, ileus, gout, mental retardation, enuresis, nocturia, polyuria, salt[medical-dictionary.thefreedictionary.com] Physicians should be aware of the possibility of gout as a clinical complication of Bartter's syndrome and of the inhibitory effects of alkalosis on urate clearance.[annals.org] Saint-Petersburg, Russia Abstract Abstract Bartter syndrome (BS) tubulopathy with autosomal recessive (AR) type of genetic inheritance, manifested hypokalemia, metabolic alkalosis, hyperreninemia[adc.bmj.com]

  • Gitelman Syndrome

    The clinical spectrum is wide and usually characterized by chronic fatigue, cramps, muscle weakness and paresthesiae.[ncbi.nlm.nih.gov] The main features of this syndrome include normal or low blood pressure, hypokalemia, metabolic alkalosis, hypomagnesemia, hypocalciuria, and hyperreninemia.[ncbi.nlm.nih.gov] Hyperplasia of the juxtaglomerular complex with hyperaldosteronism and hypokalemic alkalosis. Am. J.[dx.doi.org]

  • Hypokalemia

    Neurological examination showed a lower extremity muscle weakness with three-fifths muscular strength of the quadriceps and tibialis anterior muscle on both sides.[ncbi.nlm.nih.gov] Patients can also present with convulsions due to severe metabolic alkalosis or hypomagnesemia. Therefore, early recognition and treatment are important.[ncbi.nlm.nih.gov] Proximal muscle weakness is observed most commonly in lower extremities; cranial muscles are normal, but constipation and distention are prominent.[dovepress.com]

  • Conn Syndrome

    Low potassium may cause fatigue, muscle cramps, muscle weakness, numbness, or temporary paralysis.[endocrinediseases.org] When renin increases (due to low blood pressure, decreased blood flow to the kidneys or to a sodium deficiency), aldosterone increases; when renin decreases, aldosterone decreases.In[labtestsonline.org.au] All of the patients in this case had metabolic alkalosis. Unilateral adrenal mass was found on CT-Scan or MRI imaging.[ncbi.nlm.nih.gov]

  • Hypokalemic Nephropathy

    There is generalized muscle weakness, characterized by ventroflexion of the neck; other signs include weight loss, chronic vomiting and constipation.[medical-dictionary.thefreedictionary.com] Excessive aldosterone production may result from congenital adrenal hyperplasia, glucocorticoid treatment, some genetic defects and hyperreninemia. • Intrinsic renal potassium[symbiosisonlinepublishing.com] However, hypokalemia and metabolic alkalosis are not typical for end-stage renal disease, and renal biopsy showed typical signs of hypokalemic nephropathy.[ncbi.nlm.nih.gov]

  • Bartter Syndrome

    Clinical findings Proximal muscle weakness, failure to thrive, short stature, convulsions, tetany, cramps, ileus, gout, mental retardation, enuresis, nocturia, polyuria, salt[medical-dictionary.thefreedictionary.com] Gitelman syndrome are characterized by fluid, electrolyte, urinary, and hormonal abnormalities, including renal potassium, sodium, chloride, and hydrogen wasting; hypokalemia; hyperreninemia[msdmanuals.com] Low blood levels of potassium can cause muscle weakness, cramping, and fatigue.[webmd.com]

  • Gullner Syndrome

    Bartter Syndrome : Characterized by failure to thrive, growth deficiency, dwarfism, muscle weakness and cramps, and hypokalemia as a result of a renal potassium wasting syndrome[accessanesthesiology.mhmedical.com] Other symptoms Other symptoms, which appear during late childhood, include fatigue, muscle weakness, cramps, and recurrent carpopedal spasms.  Developmental delay and minimal[slideshare.net] Gullner HG, Gill JR Jr, Bartter FC, et al: A familial disorder with hypokalemic alkalosis, hyperreninemia, aldosteronism, high urinary prostaglandins and normal pressure that[accessanesthesiology.mhmedical.com]

  • Hyperaldosteronism

    […] spasms Muscle weakness Numbness Polyuria Polydipsia Tingling Metabolic alkalosis The causes of primary hyperaldosteronism are adrenal hyperplasia and adrenal adenoma (Conn's[en.wikipedia.org] Hyperreninemia and secondary aldosteronism have also been reported in patients with pheochromocytoma, apparently as a result of functional renal artery stenosis.[emedicine.medscape.com] Why then does hyperaldosteronism cause alkalosis?[forums.studentdoctor.net]

  • Secondary Aldosteronism

    weakness Numbness Treatment Primary hyperaldosteronism caused by an adrenal gland tumor is usually treated with surgery.[account.allinahealth.org] Bartter syndrome is associated with hypokalemic alkalosis, hyperreninemia, and hyperaldosteronism, with normal blood pressure.[usmle.net] There may be hypertension, hypokalemia, alkalosis, muscular weakness, polyuria, and polydipsia.[medical-dictionary.thefreedictionary.com]

  • Antenatal Bartter Syndrome

    Low blood levels of potassium can cause muscle weakness, cramping, and fatigue.[webmd.com] Rofecoxib suppressed hyperreninemia to a similar extent as indomethacin.[ncbi.nlm.nih.gov] Abstract Antenatal Bartter syndrome is a variant of inherited renal-tubular disorders associated with hypokalemic alkalosis.[ncbi.nlm.nih.gov]

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