In addition to causing respiratory insufficiency, RDS increases risk of intraventricular hemorrhage, tension pneumothorax, bronchopulmonary dysplasia, sepsis, and death.
[msdmanuals.com]
Tachypnea, refractory hypoxemia (hallmark sign and symptoms), cyanosis, mental status changes, abnormal lungs sounds like crackles in the late stages, tachycardia, respiratory alkalosis
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Lung damage results in leakage of fluid into alveoli, leading to non-cardiogenic pulmonary edema and decreased arterial oxygenation.
[radiopaedia.org]