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7,584 Possible Causes for All Reported Mutations Have Occurred De Novo, Pallor, Pediatric Disorder

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  • Anemia

    Pallor has poor sensitivity for predicting mild anemia, but correlates well with severe anemia. 11 – 13 One study showed that physical examination findings of pallor of the[aafp.org] One of the most common pediatric disorders, anemia has many potential causes. Anemia is often a symptom of a disease rather than a disease itself.[childrenshospital.org] In addition to an experienced, compassionate nurse coordinator (who provides your child and family support, education and care coordination), Nemours’ pediatric blood disorder[nemours.org]

    Missing: All Reported Mutations Have Occurred De Novo
  • Iron Deficiency Anemia

    Blood Disorders Center, an integrated pediatric hematology and oncology partnership between Dana-Farber Cancer Institute and Boston Children's Hospital.[childrenshospital.org] A 19-month-old girl with a history of asthma and atopic dermatitis presented to her pediatrician because of parental concerns of pallor and fatigue.[ncbi.nlm.nih.gov] A 3-year-old boy presented with recurrent strokes and pallor. Hematological investigations revealed severe iron deficiency anemia without thrombocytosis.[ncbi.nlm.nih.gov]

    Missing: All Reported Mutations Have Occurred De Novo
  • Migraine

    The prodrome can consist of yawning, fluid retention, pallor, nausea, light sensitivity, or mood changes, including sadness or irritability.[britannica.com] […] mechanisms that may explain the association between the two disorders, and the effects of treatment.[ncbi.nlm.nih.gov] Symptoms include abdominal pain without a gastrointestinal cause (may last up to 72 hours), nausea, vomiting, and flushing or paleness (pallor).[healthcommunities.com]

    Missing: All Reported Mutations Have Occurred De Novo
  • Hereditary Spherocytosis

    Pallor (100%), icterus (67%), undocumented fever (28%), splenomegaly (96%) and hepatomegaly (73%) were the most frequent findings. Cholelithiasis was observed in 26%.[ncbi.nlm.nih.gov] The 2003 Healthcare Cost and Utilization Project (HCUP) Kids’ Inpatient Database (KID), a robust and widely used measure of pediatric disorders, has estimated that the number[touchoncology.com] Incidentally, the parents provided a history of repeated episodes of pallor and jaundice since she was two and half years old.[ncbi.nlm.nih.gov]

    Missing: All Reported Mutations Have Occurred De Novo
  • Posthemorrhagic Anaemia of the Newborn

    Pallor persists in spite of administration of oxygen. Under such conditions immediate re-expansion of blood volume is imperative and lifesaving.[pediatrics.aappublications.org] Succinct, targeted coverage of normal childhood growth and development, as well as the diagnosis, management, and prevention of common pediatric diseases and disorders, make[books.google.com] In these cases bleeding is usually suspected because of clinical signs of blood loss such as pallor and shock.[pedsinreview.aappublications.org]

    Missing: All Reported Mutations Have Occurred De Novo
  • Diabetes Mellitus Type 1

    Hypoglycemia is defined as a plasma glucose The adrenergic signs and symptoms include pallor, sweating, trembling, palpitations, and anxiety.[clinicaladvisor.com] Adult and pediatric endocrinologists, specialists in treating hormonal disorders and disorders of the endocrine system, manage patients with diabetes.[medicinenet.com] […] diseases of the endocrine system, such as diabetes and growth disorders.[kidshealth.org]

    Missing: All Reported Mutations Have Occurred De Novo
  • Leukemia

    Physical examination reveals pallor and multiple ecchymoses on his arms, legs, and trunk.[doi.org] […] oncologist at Dana-Farber/Boston Children’s Cancer and Blood Disorders Center.[theguardian.com] Over 50% of children with leukaemia have palpable livers, palpable spleens, pallor, fever or bruising on diagnosis.[ncbi.nlm.nih.gov]

    Missing: All Reported Mutations Have Occurred De Novo
  • Abdominal Migraine

    Abdominal migraine, primarily a pediatric disorder, is often under diagnosed and misunderstood as it can mimic several other systemic and often potentially dangerous clinical[medcraveonline.com] […] syndrome comprising episodes of midline abdominal pain of sufficient severity to interfere with normal activities and lasting for prolonged periods, frequently accompanied by pallor[ncbi.nlm.nih.gov] During abdominal pain at least 2 of the following: 1. anorexia 2. nausea 3. vomiting 4. pallor E.[en.wikipedia.org]

    Missing: All Reported Mutations Have Occurred De Novo
  • Congenital Dyserythropoietic Anemia

    Age at onset of pallor ranged from birth to 9 years. Blood transfusion requirements varied from nil to monthly. This is the first report of CDA type I from India.[ncbi.nlm.nih.gov] Hereditary Elliptocytosis and Related Disorders Pediatric Lead Toxicity Pediatric Megaloblastic Anemia Pediatric Myelodysplastic Syndrome Sickle Cell Anemia Transient Erythroblastopenia[emedicine.medscape.com] On the other hand chronic blood loss is characterized by pallor out of proportion to distress and possibly signs of congestive cardiac failure, including hepatomegaly.[oncologynurseadvisor.com]

    Missing: All Reported Mutations Have Occurred De Novo
  • Nephroblastoma

    Non-specific symptoms are present in less than 1/3 children: subfebrility, weakness, pallor, loss of appetite constipation, abdominal pain 10–30 % patients develop micro or[telemedicina.med.muni.cz] Denys-Drash syndrome: relating a clinical disorder to genetic alterations in the tumor suppressor gene WT1. J Pediatr. 1993 Nov. 123(5):673-8. [Medline].[docdoc.com.sg] Additional symptoms that should prompt concern include pallor, petechiae or ecchymoses, bone pain and significant weight loss.[aafp.org]

    Missing: All Reported Mutations Have Occurred De Novo

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