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976 Possible Causes for Allelic Disorder to Parkinson Disease Type 1, Bradykinesia, Lewy Bodies in the Brain

  • Dementia with Lewy Bodies

    He showed bradykinesia and small step gait with supranuclear vertical gaze palsy, especially upward gaze palsy. He was started on levodopa therapy but without response.[ncbi.nlm.nih.gov] […] neurons, etc. 2. numerous Lewy bodies in the brain stem and diencephalon, 3. peculiar swollen neurons with intracytoplasmic, eosinophilic and argentophilic inclusions (“Lewy-like-bodies[doi.org] […] clinical features include: recurrent visual hallucinations; cognitive fluctuations; REM sleep behaviour disorder; and one or more spontaeous cardinal features of parkinsonism: bradykinesia[bestpractice.bmj.com]

  • Parkinson-Dementia Syndrome

    Postural instability and bradykinesia is noted on physical exam.[medbullets.com] Parkinson’s disease has Lewy bodies in key areas of the brain that control movement; Lewy bodies are composed of the protein alpha-synuclein.[michaeljfox.org] Dementia (especially visuospatial and executive dysfunction) Extrapyramidal motor symptoms ( bradykinesia, rigor) Visual hallucinations and paranoid episodes Episodic impairment[amboss.com]

    Missing: Allelic Disorder to Parkinson Disease Type 1
  • Parkinson's Disease Type 3

    Parkinson's disease is a neurodegenerative disorder associated with muscle rigidity, tremor, and bradykinesia.[symptoma.com] Final diagnosis is usually made by the presence of lewy bodies in the brain during autopsy.[orpha.net] Lewy bodies are also found in several other brain disorders, including Lewy body dementia (LBD).[alz.org]

    Missing: Allelic Disorder to Parkinson Disease Type 1
  • Parkinson's Disease

    Table 1 Parkinson’s disease symptoms Bradykinesia Bradykinesia refers to slowness of movement and is the most characteristic clinical feature of PD, although it may also be[web.archive.org] Structural Brain Correlates of Attention Dysfunction in Lewy Body Dementias and Alzheimer’s Disease .[doi.org] Lewy bodies : A person with PD may have clumps of protein in their brain known as Lewy bodies. Lewy body dementia is a different condition, but it has links with PD.[medicalnewstoday.com]

    Missing: Allelic Disorder to Parkinson Disease Type 1
  • Secondary Parkinsonism

    Gradually, bradykinesia diminished slightly and vigilance increased little.[ncbi.nlm.nih.gov] Some brain problems, such as Lewy body disease, are not reversible.[health.firstlighthealthsystem.org] On observing for 5 subsequent days, there was no improvement in her bradykinesia or rigidity.[mdsabstracts.org]

    Missing: Allelic Disorder to Parkinson Disease Type 1
  • Juvenile Paralysis Agitans of Hunt

    32 HP:0002067 9 parkinsonism 32 HP:0001300 Symptoms via clinical synopsis from OMIM: 57 Neuro: dysarthria gait disturbance tremor rigidity bradykinesia more Misc: onset in[malacards.org] Summary A clinico-pathological case report on a case of juvenile Parkinson's disease (JPD) with widespread Lewy bodies (LBs) in the brain is presented with comparative morphological[link.springer.com] Diseases related with Melanoma and Bradykinesia In the following list you will find some of the most common rare diseases related to Melanoma and Bradykinesia that can help[mendelian.co]

    Missing: Allelic Disorder to Parkinson Disease Type 1
  • Shy Drager Syndrome

    While the limited and transient beneficial effect of levodopa on the bradykinesia in our case is possibly due to the progressive loss of striatal dopaminergic receptors seen[ncbi.nlm.nih.gov] The presence of alpha-synuclein in GCIs provides a link with Parkinson's disease, dementia with Lewy bodies, and neurodegeneration with brain iron accumulation, type 1 (or[ncbi.nlm.nih.gov] For patients afflicted with this condition, rigidity and bradykinesia are the primary extrapyramidal symptoms which are present.[ncbi.nlm.nih.gov]

    Missing: Allelic Disorder to Parkinson Disease Type 1
  • Progressive Supranuclear Palsy

    UPDRS total motor scores and subscores for bradykinesia and axial motor deficits did not correlate with R2* values of the five brain regions.[ncbi.nlm.nih.gov] There were 67-year-old woman with a phenotype of multiple system atrophy and a 70-year-old man with a phenotype of dementia with Lewy bodies.[ncbi.nlm.nih.gov] While many parkinsonian disorders such as Parkinson's disease, Lewy body dementia, and multiple system atrophy are classified as synucleinopathies, progressive supranuclear[ncbi.nlm.nih.gov]

    Missing: Allelic Disorder to Parkinson Disease Type 1
  • X-linked Parkinsonism-Spasticity Syndrome

    UniProtKB/Swiss-Prot : 75 Parkinsonism with spasticity, X-linked: A syndrome characterized by parkinsonian features, such as cogwheel rigidity, resting tremor and bradykinesia[malacards.org] Lewy body disease, sometimes called Lewy body dementia, occurs when abnormal proteins known as Lewy bodies form in the brain.[rush.edu] Format Definition A syndrome characterized by parkinsonian features, such as cogwheel rigidity, resting tremor and bradykinesia, and variably penetrant spasticity.[uniprot.org]

    Missing: Allelic Disorder to Parkinson Disease Type 1
  • Prion Disease

    The first patient experienced progressive bradykinesia, ataxia, and slurred speech developing over a two-week period.[web.archive.org] What’s more, when healthy donor brain cells were grafted into the brain of Parkinson’s patients as an experimental treatment, the donor cells sometimes developed Lewy bodies[blogs.discovermagazine.com] The problem, they say, is that the progression of Lewy bodies through the brain in Parkinson’s disease doesn’t follow a prion-like pattern.[blogs.discovermagazine.com]

    Missing: Allelic Disorder to Parkinson Disease Type 1