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616 Possible Causes for Allelic Disorder to Parkinson Disease Type 1, Cogwheel Rigidity, Lewy Bodies in the Brain

  • Dementia with Lewy Bodies

    […] neurons, etc. 2. numerous Lewy bodies in the brain stem and diencephalon, 3. peculiar swollen neurons with intracytoplasmic, eosinophilic and argentophilic inclusions (“Lewy-like-bodies[doi.org] bodies in their brains.[hopkinsmedicine.org] Lewy bodies are also found in the brain tissue of people with Parkinson’s disease (PD) and AD, although the Lewy bodies are generally located in different parts of the brain[columbianeurology.org]

  • Parkinson-Dementia Syndrome

    Parkinson’s disease has Lewy bodies in key areas of the brain that control movement; Lewy bodies are composed of the protein alpha-synuclein.[michaeljfox.org] The way someone is affected by DLB will depend partly on where the Lewy bodies are in the brain: Lewy bodies at the base of the brain are closely linked to problems with movement[alzheimers.org.uk] Lewy bodies are tiny clumps of abnormal proteins produced by the brain when its cells are not working properly.[dailymail.co.uk]

    Missing: Allelic Disorder to Parkinson Disease Type 1
  • Parkinson's Disease

    Resting tremor of extremity Bradykinesia Cogwheel rigidity of limbs Masked facies (lack of expression or facial animation) Postural instability Micrographia Short stepped[clinicaladvisor.com] Structural Brain Correlates of Attention Dysfunction in Lewy Body Dementias and Alzheimer’s Disease .[doi.org] In parkinsonism the rigidity can be uniform ("lead-pipe rigidity") or ratchety ("cogwheel rigidity").[en.wikipedia.org]

    Missing: Allelic Disorder to Parkinson Disease Type 1
  • Parkinson's Disease Type 3

    Final diagnosis is usually made by the presence of lewy bodies in the brain during autopsy.[orpha.net] Lewy bodies are also found in several other brain disorders, including Lewy body dementia (LBD).[alz.org] Dementia with Lewy bodies (DLB) lacks specific diagnostic markers on brain MRI, although mild general atrophy can be seen in some cases.[journalofparkinsonsdisease.com]

    Missing: Allelic Disorder to Parkinson Disease Type 1
  • Juvenile Paralysis Agitans of Hunt

    The rigidity has a rhythmic quality referred to as cogwheel rigidity (Negro’s sign), presumably due to the superimposition of the tremor.[neupsykey.com] Summary A clinico-pathological case report on a case of juvenile Parkinson's disease (JPD) with widespread Lewy bodies (LBs) in the brain is presented with comparative morphological[link.springer.com] Cogwheel rigidity is thought to be due to the combination of rigidity and tremor.[biotechnologyforums.com]

    Missing: Allelic Disorder to Parkinson Disease Type 1
  • Secondary Parkinsonism

    She drooled, and had dysarthria, a shuffling gait, and cogwheel rigidity.[mdedge.com] Some brain problems, such as Lewy body disease, are not reversible.[health.firstlighthealthsystem.org] rigidity".[explainmedicine.com]

    Missing: Allelic Disorder to Parkinson Disease Type 1
  • Neuroleptic Malignant Syndrome

    Motor abnormalities: Patients may have generalized, severe muscle rigidity (sometimes with simultaneous tremor, leading to cogwheel rigidity), or, less often, dystonias, chorea[msdmanuals.com] RISK FACTORS NMS may be more likely to develop in patients with dehydration, agitation, low serum iron, underlying brain damage (Lewy body dementia and Parkinson) and catatonia[flipper.diff.org] We present video evidence of the effectiveness of dantrolene in reducing muscular rigidity, tremor and cogwheel phenomena in a patient with NMS.[ccforum.com]

    Missing: Allelic Disorder to Parkinson Disease Type 1
  • Postencephalitic Parkinson Disease

    Cogwheel rigidity will be appreciated with passive movement of the patients limb.[thebigl.co] body disease: PD that has spread to include many parts of the brain and usually is characterized by both parkinsonism and dementia Diuretics: drugs that help the body get[books.google.de] Parkinson's disease is recognized by the presence of at least three of four cardinal signs: resting tremor, cogwheel rigidity, bradykinesia/akinesia, and postural reflex impairment[parkinsonsmi.org]

    Missing: Allelic Disorder to Parkinson Disease Type 1
  • X-linked Parkinsonism-Spasticity Syndrome

    UniProtKB/Swiss-Prot : 75 Parkinsonism with spasticity, X-linked: A syndrome characterized by parkinsonian features, such as cogwheel rigidity, resting tremor and bradykinesia[malacards.org] Lewy body disease, sometimes called Lewy body dementia, occurs when abnormal proteins known as Lewy bodies form in the brain.[rush.edu] Aggregated α-synuclein is found in hallmark lesions called Lewy bodies and Lewy neurites in the brain of people who have Parkinson’s disease.[bitanlab.neurology.ucla.edu]

    Missing: Allelic Disorder to Parkinson Disease Type 1
  • Bradykinesia

    ), or Parkinsonism or Parkinsonian-like conditions (e.g., cogwheel rigidity, bradykinesia, postural instability), or other neurological syndromes as defined in the Note below[glosbe.com] Lewy body: Brain cells that have abnormal pigmented spheres inside them. They are found in the damaged parts of the brain in people with Parkinson's disease.[webmd.com] Aggregation of the protein alpha-synuclein is found in Lewy bodies, a pathological hallmark of Parkinson's disease.[michaeljfox.org]

    Missing: Allelic Disorder to Parkinson Disease Type 1