Create issue ticket

328 Possible Causes for Allelic Disorder to Parkinson Disease Type 1, Cogwheel Rigidity, Poor Spontaneous Movements

  • Parkinson's Disease

    Resting tremor of extremity Bradykinesia Cogwheel rigidity of limbs Masked facies (lack of expression or facial animation) Postural instability Micrographia Short stepped[clinicaladvisor.com] In parkinsonism the rigidity can be uniform ("lead-pipe rigidity") or ratchety ("cogwheel rigidity").[en.wikipedia.org] rigidity (catching and releasing) or lead-pipe rigidity (continuously rigid); rigidity must be distinguished from spasticity, which has only increased flexor tone; rigidity[aafp.org]

    Missing: Allelic Disorder to Parkinson Disease Type 1
  • Parkinson's Disease Type 3

    Parkinson's disease type 3 (PD3) is a form of Parkinson's disease that is inherited in an autosomal dominant manner. The underlying mutation has not yet been identified, but PD3 has been related to a 2.5 Mb-locus on the short arm of chromosome 2. To date, PD3 has been diagnosed in distinct families in Europe and[…][symptoma.com]

    Missing: Allelic Disorder to Parkinson Disease Type 1
  • Dementia with Lewy Bodies

    This article provides an overview of the clinical features, neuropathologic findings, diagnostic criteria, and management of dementia with Lewy bodies (DLB) and Parkinson disease dementia (PDD), together known as the Lewy body dementias. DLB and PDD are common, clinically similar syndromes that share characteristic[…][ncbi.nlm.nih.gov]

    Missing: Poor Spontaneous Movements
  • Juvenile Paralysis Agitans of Hunt

    […] or loss of spontaneous movement (bradykinesia) Lack of balance Poor coordination Tires easily Handwriting becomes difficult due to shaking hands or weakened, nonresponsive[cookchildrens.org] The rigidity has a rhythmic quality referred to as cogwheel rigidity (Negro’s sign), presumably due to the superimposition of the tremor.[neupsykey.com] Cogwheel rigidity is thought to be due to the combination of rigidity and tremor.[biotechnologyforums.com]

    Missing: Allelic Disorder to Parkinson Disease Type 1
  • Fracture

    Ann Anat. 2018 Mar;216:120-124. doi: 10.1016/j.aanat.2017.12.005. Epub 2018 Jan 1. Author information 1 Studio Fonzar, Strada dei Tigli, 54, 33030 Campoformido, UD, Italy. Electronic address: federica.fonzar@gmail.com. 2 Department of Stomatology, Universitat de València (Spain) Clínica Odontológica, Calle Gascó Oliag, 1, 46010[…][ncbi.nlm.nih.gov]

    Missing: Allelic Disorder to Parkinson Disease Type 1 Cogwheel Rigidity
  • Multiple Myeloma

    The monoclonal gammopathies are a group of disorders associated with monoclonal proliferation of plasma cells. The characterization of specific entities is an area of difficulty in clinical practice. The International Myeloma Working Group has reviewed the criteria for diagnosis and classification with the aim of[…][ncbi.nlm.nih.gov]

    Missing: Allelic Disorder to Parkinson Disease Type 1 Poor Spontaneous Movements
  • Biotin-Responsive Basal Ganglia Disease

    rigidity, dystonia, quadriparesis, and eventual death, if left untreated.[ncbi.nlm.nih.gov] rigidity, dystonia and quadriparesis.[ncbi.nlm.nih.gov] (BBGD) is a recessive disorder with childhood onset that presents as a subacute encephalopathy, with confusion, dysarthria, and dysphagia, and that progresses to severe cogwheel[ncbi.nlm.nih.gov]

    Missing: Allelic Disorder to Parkinson Disease Type 1 Poor Spontaneous Movements
  • 6-Pyruvoyl-Tetrahydropterin Synthase Deficiency

    Symptoms often include poor sucking, decreased spontaneous movements, floppiness, microcephaly, low birth weight, and early appearance of neurologic signs in the neonatal[medlink.com] Commonly reported symptoms are initial truncal hypotonia, subsequent appendicular hypertonia, bradykinesia, cogwheel rigidity, generalized dystonia, and marked diurnal fluctuation[en.wikipedia.org] They may have poor suckling, decreased spontaneous movements, and a floppy-baby appearance.[emedicine.medscape.com]

    Missing: Allelic Disorder to Parkinson Disease Type 1
  • Neuroleptic Malignant Syndrome

    Motor abnormalities: Patients may have generalized, severe muscle rigidity (sometimes with simultaneous tremor, leading to cogwheel rigidity), or, less often, dystonias, chorea[msdmanuals.com] We present video evidence of the effectiveness of dantrolene in reducing muscular rigidity, tremor and cogwheel phenomena in a patient with NMS.[ccforum.com] Muscle rigidity, cogwheel phenomena and tremor disappeared within 10 min (video footage is available in Additional file 2 ), but they gradually reappeared within an hour.[ccforum.com]

    Missing: Allelic Disorder to Parkinson Disease Type 1 Poor Spontaneous Movements
  • Parkinson-Dementia Syndrome

    Dementia represents one of the most challenging health problems. Despite intense research, available therapies have thus far only achieved modest results. Deep brain stimulation (DBS) is an effective treatment option for some movement disorders and is under study for psychiatric applications. Recently, diencephalic[…][ncbi.nlm.nih.gov]

    Missing: Allelic Disorder to Parkinson Disease Type 1 Poor Spontaneous Movements