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727 Possible Causes for Allelic Disorder to Parkinson Disease Type 1, Lewy Bodies in the Brain, Parasomnia

  • Dementia with Lewy Bodies

    Abstract Idiopathic rapid eye movement (REM) sleep behavior disorder (RBD) is a parasomnia clinically linked with the alpha-synucleinopathies multiple systems atrophy (MSA[ncbi.nlm.nih.gov] […] neurons, etc. 2. numerous Lewy bodies in the brain stem and diencephalon, 3. peculiar swollen neurons with intracytoplasmic, eosinophilic and argentophilic inclusions (“Lewy-like-bodies[doi.org] Abstract Rapid eye movement sleep behavior disorder (RBD) is a parasomnia, with abnormal dream-enacting behavior during the rapid eye movement (REM) sleep.[ncbi.nlm.nih.gov]

  • Secondary Parkinsonism

    Some brain problems, such as Lewy body disease, are not reversible.[health.firstlighthealthsystem.org] Brain problems, such as Lewy body disease, are not reversible.[irmcphysicians.com] Causes Secondary parkinsonism may be caused by health problems, including: Brain injury Diffuse Lewy body disease (a type of dementia ) Encephalitis HIV/AIDS Meningitis Multiple[health.firstlighthealthsystem.org]

    Missing: Allelic Disorder to Parkinson Disease Type 1
  • Alzheimer Disease

    ., et al. (1996) Purification and characterization of Lewy bodies from the brains of patients with diffuse Lewy body disease. Am. J. Pathol. 148 ( 5 ), 1517–1529.[doi.org] Alzheimer disease (AD), in whom Lewy body variant was thereafter clinically diagnosed.[ncbi.nlm.nih.gov] […] have dementia with Lewy bodies.[adrc.pitt.edu]

    Missing: Allelic Disorder to Parkinson Disease Type 1
  • Orthostatic Hypotension

    “Orthostatic Hypotension in Parkinson’s Disease, Multiple System Atrophy, and Lewy Body Dementia” By the Stanford Movement Disorder Center and Brain Support Network, September[parkinsons.stanford.edu] Neuropathological studies have also demonstrated Lewy body pathology in the locus coeruleus; the main source of noradrenaline in the brain.[ncbi.nlm.nih.gov] […] shows changes in putamen, pons, middle cerebellar peduncle, and cerebellum Autonomic support Parkinson disease Lewy bodies in cytoplasm of CNS neurons, resulting in extrapyramidal[aafp.org]

    Missing: Allelic Disorder to Parkinson Disease Type 1
  • Parasomnia Type Sleepwalking

    NREM parasomnia onset was reported after the age of 30 years in 6.8% (5/74).[ncbi.nlm.nih.gov] The study found that men who act out their dreams while asleep, by walking, talking or hitting, were five times more likely to have dementia with Lewy bodies, a progressive[blog.sleepnumber.com] An important gene associated with Parasomnia, Sleepwalking Type is PSMNSW (Parasomnia, Sleepwalking Type). Related phenotype is sleep terror.[malacards.org]

    Missing: Allelic Disorder to Parkinson Disease Type 1
  • REM Sleep Behavior Disorder

    The unilateral small lesion of the pontine tegmentum could be responsible for the parasomnia overlap disorder as in other rare lesional cases.[ncbi.nlm.nih.gov] Examination of brain revealed Lewy bodies as well as marked neuronal loss in brainstem monoaminergic nuclei-particularly locus coeruleus and substantia nigra-that inhibit[ncbi.nlm.nih.gov] These REM sleep neurobehavioral disorders constitute another category of parasomnia, replicate findings from 21 years ago in cats receiving pontine tegmental lesions, and[doi.org]

    Missing: Allelic Disorder to Parkinson Disease Type 1
  • Adjustment Disorder

    331.9G31.9Major neurocognitive disorder with Lewy bodies, Possible [Lewy body disease ] Major neurocognitive disorder with Lewy bodies, Probable [331.82 ] 294.11[G31.83 ][dr-bob.org] […] injury 331.83G31.84Mild neurocognitive disorder with Lewy bodies 331.83G31.84Mild vascular neurocognitive disorder 301.81F60.81Narcissistic personality disorder Narcolepsy[dr-bob.org] […] injury with loss of consciousness of unspecified duration, sequela (ICD-10-CM) ] Major neurocognitive disorder due to traumatic brain injury, Without behavioral disturbance[dr-bob.org]

    Missing: Allelic Disorder to Parkinson Disease Type 1
  • Parkinson-Dementia Syndrome

    Many patients have rapid eye movement (REM) sleep behavior disorder, a parasomnia characterized by vivid dreams without the usual physiologic paralysis of skeletal muscles[merckmanuals.com] Parkinson’s disease has Lewy bodies in key areas of the brain that control movement; Lewy bodies are composed of the protein alpha-synuclein.[michaeljfox.org] The way someone is affected by DLB will depend partly on where the Lewy bodies are in the brain: Lewy bodies at the base of the brain are closely linked to problems with movement[alzheimers.org.uk]

    Missing: Allelic Disorder to Parkinson Disease Type 1
  • Behavior Disorder

    We propose that POD is a distinct pathophysiologic parasomnia. Further research to identify the underlying mechanism is needed.[ncbi.nlm.nih.gov] bodies, and multiple system atrophy, which are known to initially cause degeneration in the caudal brain stem structures where rapid eye movement sleep circuits are located[ncbi.nlm.nih.gov] The subjects had histories of behavioral parasomnias as well as positive family histories of parasomnia.[ncbi.nlm.nih.gov]

    Missing: Allelic Disorder to Parkinson Disease Type 1
  • Depression

    A depression in geology is a landform sunken or depressed below the surrounding area. Depressions form by various mechanisms. Erosion-related: Blowout: a depression created by wind erosion typically in either a partially vegetated sand dune ecosystem or dry soils (such as a post-glacial loess environment). Glacial[…][en.wikipedia.org]

    Missing: Allelic Disorder to Parkinson Disease Type 1 Lewy Bodies in the Brain