Almond-Shaped Eyes: Causes & Reasons

Possible Causes for Almond-Shaped Eyes

The clinical appearance of PWS includes dysmorphic facial features with almond-shaped eyes, a narrow bifrontal diameter, and a thin upper lip; short stature; central obesity [ncbi.nlm.nih.gov]

[…] incomplete puberty Scoliosis Short stature Unusually fair skin Underdeveloped genitals Strabismus Small hands and feet Distinctive facial features such as a narrow forehead, almond-shaped [childrensmercy.org]

Different from western patients, the 20 Asian patients exhibited at least five of the following typical features: prominent forehead, narrow face, almond-shaped eyes, small [ncbi.nlm.nih.gov]

Velocardiofacial Syndrome

[…] include: cleft palate, usually of the soft palate (the roof of the mouth nearest the throat which is behind the bony palate); heart problems; similar faces (elongated face, almond-shaped [wiki.ggc.edu]

[…] includes: cleft palate, usually of the soft palate (the roof of the mouth nearest the throat which is behind the bony palate); heart problems; similar faces (elongated face, almond-shaped [healthieryou.com]

Typical facial features include a long face, small almond shaped eyes, a wide bridged nose, and malformations of the ear. [genedx.com]

Trisomy 21

A flattened face — especially across the nose — and upward-slanted, almond-shaped eyes are two of the common physical features of Down syndrome. [everydayhealth.com]

Individuals with DS may have certain physical attributes including: Almond-shaped eyes with striking Brushfield spots (small, white, crescent-shaped markings) on the irises [babycenter.com]

Some common physical features of Down syndrome include: A flattened face, especially the bridge of the nose Almond-shaped eyes that slant up A short neck Small ears A tongue [cdc.gov]

X-Linked Syndromic Intellectual Disability Type Nascimento

[…] type Nascimento (MIM #300860), caused by mutations in UBE2A (MIM *312180), is characterized by craniofacial dysmorphism (synophrys, prominent supraorbital ridges, deep-set, almond-shaped [ncbi.nlm.nih.gov]

[…] disability type Nascimento (MIM #300860), due to mutations in (MIM *312180), is normally seen as a craniofacial dysmorphism (synophrys, prominent supraorbital ridges, deep-set, almond-shaped [eyesoftheelephants.com]

Facial phenotype is characterized by a broad face, flat midface, synophrys and/or prominent eyebrows, almond shaped eyes, low nasal bridge, prominent columella of the nose [ojrd.biomedcentral.com]

CK Syndrome

bushy eyebrows XLD SLC9A6 #300243 CK SYNDROME Strabismus, epicanthal folds, upslanting palpebral fissures, almond-shaped eyes XLR NSDHL #300831 COCKAYNE SYNDROME Pigmentary [eyewiki.aao.org]

Abnormality of head or neck Almond-shaped palpebral fissure Dental crowding Epicanthal fold High palate Long face Narrow face Prominent nasal bridge Upslanted palpebral fissure [ncbi.nlm.nih.gov]

[…] pigmentation of trabecular meshwork, deposited pigment on Schwalbe's line AD - %600510 PRADER-WILLI SYNDROME Refractive errors, strabismus, upslanting palpebral fissures, almond-shaped [eyewiki.aao.org]

Absent Thumb - Short Stature - Immunodeficiency Syndrome

Upon examination, he presented with short stature, neck webbing, and craniofacial dysmorphic features comprising full cheeks, prominent widened nasal bridge, almond-shaped [bmcmedgenet.biomedcentral.com]

Congenital neurobehavioral disorder characterized by rounded face, low forehead, almond shaped eyes, squinting, hypogonadism, hypotonia, insatiable appetite leading to obesity [icd10data.com]

(Osteogenesis imperfecta) AD - Connective tissue disorder - Mutation type 1 collagen Binge eating, hypotonia, hypogonadism, feeding problem in infancy Dysmorphic facies- almond-shaped [quizlet.com]

Weaver Syndrome

Weaver syndrome is a congenital overgrowth disorder that often displays tall stature, dysmorphic facial features (hypertelorism, broad forehead, almond-shaped eyes, pointed [taylorfrancis.com]

I have typical characteristics of Weaver Syndrome; large birth size, accelerated growth, atypical face view (big ears, big tongue, small chin, almond-shaped eyes), tall in [sites.google.com]

Baker-Gordon Syndrome

The patients had similar mild dysmorphic features, including prominent high forehead, horizontal low-set eyebrows, mild epicanthus, almond-shaped eyes, short nose with prominent [findzebra.com]

The eyes have been described as "almond-shaped". Strabismus and nystagmus are commonly present. [disorders.eyes.arizona.edu]

You are here Search For A Disorder Clinical Characteristics Ocular Features: Poor visual acuity described as central in origin with poor eye contact. [disorders.eyes.arizona.edu]

2p21 Deletion Syndrome

Clinical description Dysmorphic features include frontal bossing, almond-shaped eyes, long eyelashes, depressed nasal bridge, and large, posteriorly rotated ears. [orpha.net]

Dysmorphic features include frontal bossing, almond-shaped eyes, long eyelashes, depressed nasal bridge, and large, posteriorly rotated ears. [ncbi.nlm.nih.gov]

Congenital Disorder of Glycosylation Type 1N

These may include inverted nipples, poor muscle tone, almond shaped eyes which are crossed, a large forehead, an unusual distribution of body fat, and abnormal genitals. [myriad.com]

Galloway-Mowat Syndrome Type 7

Dysmorphic features include short stature, facial dysmorphism (including a high, narrow forehead, hypertelorism, almond-shape eyes, large and low set ears, and micrognathia [orpha.net]

The baby displayed various features of facial dysmorphism (microcephaly, almond-shaped eye, abnormally high but narrow forehead, ocular hypertelorism, depressed nasal bridge [bmcmedgenet.biomedcentral.com]

Galloway-Mowat Syndrome Type 3

Her facial features had typical beaked nose, low-set, large ears, almond-shaped eyes, narrow forehead, coarse hair, and hypertelorism (Fig. 1). [scielo.mec.pt]

The baby displayed various features of facial dysmorphism (microcephaly, almond-shaped eye, abnormally high but narrow forehead, ocular hypertelorism, depressed nasal bridge [ncbi.nlm.nih.gov]

14-month-old girl with infantile nephrotic syndrome having a protein to creatinine ratio of 6.1, microcephaly, low-set ears, hypertelorism, beaked nose, narrow-forehead, almond-shaped [scielo.mec.pt]

Microphthalmia - Ankyloblepharon - Intellectual Disability Syndrome

bushy eyebrows/XLD/SLC9A6/#300243 CK SYNDROME/Strabismus, epicanthal folds, upslanting palpebral fissures, almond-shaped eyes/XLR/NSDHL/#300831 COCKAYNE SYNDROME/Pigmentary [eyewiki.org]

bushy eyebrows XLD SLC9A6 #300243 CK SYNDROME Strabismus, epicanthal folds, upslanting palpebral fissures, almond-shaped eyes XLR NSDHL #300831 COCKAYNE SYNDROME Pigmentary [eyewiki.aao.org]

[…] pigmentation of trabecular meshwork, deposited pigment on Schwalbe’s line/AD/-/%600510 PRADER-WILLI SYNDROME/Refractive errors, strabismus, upslanting palpebral fissures, almond-shaped [eyewiki.org]

Congenital Disorder of Glycosylation Type 2M

These may include inverted nipples, poor muscle tone, almond shaped eyes which are crossed, a large forehead, an unusual distribution of body fat, and abnormal genitals. [myriad.com]

Disorder of Sex Development - Intellectual Disability Syndrome

Children may be born with almond-shaped eyes, a narrowing of the head at the temples, a turned-down mouth and a thin upper lip. Poor sucking reflex. [mayoclinic.org]

Autosomal Dominant Mental Retardation Type 1

These may or may not include: a broad forehead a uni-brow thick and/or arched eyebrows eye abnormalities almond-shaped eyes a short up-turned nose other nasal abnormalities [2q23.org]

DiGeorge Syndrome

Facial characteristics include small ears with a squared upper ear, almond shaped eyes, flattened bridge of the nose, pear-shaped nose, and small mouth and chin. [day2dayparenting.com]

Typical facial features include a long face, small almond shaped eyes, a wide bridged nose, and malformations of the ear. [genedx.com]

Chromosome 18q Duplication

eyes. [spandidos-publications.com]

[…] addition, the patient displayed psychomotor retardation, developmental delay and a long face, phenotypes which become evident with developing CdCS, however, she also had almond-shaped [spandidos-publications.com]

[…] determined that the patient presented features that have not previously been described in other patients, such as transverse flexion creases, a downturned mouth, a long face and almond-shaped [spandidos-publications.com]

Partial Monosomy 3p

[…] clinodactyly of the thumb, coarctation of the aorta, patent ductus arteriosus, peripheral pulmonary stenosis, atrial septal defect, microcephaly, brachycephaly, a small oval face, almond-shaped [pubmed.ncbi.nlm.nih.gov]

eyes, a down-turned mouth, a widened nasal bridge, hypertelorism, epicanthic folds, long philtrum, low-set large ears and but no craniosynostosis. [pubmed.ncbi.nlm.nih.gov]

X-Linked Syndromic Intellectual Disability Type Abidi

Facial phenotype is characterized by a broad face, flat midface, synophrys and/or prominent eyebrows, almond shaped eyes, low nasal bridge, prominent columella of the nose [link.springer.com]

The facial phenotype is characterized by a broad face, flat midface, almond shaped eyes, ocular hypertelorism, low nasal bridge, prominent columella of the nose, hypoplastic [link.springer.com]

19p13.13 Microdeletion Syndrome

[…] include: Developmental delays Speech and language delays that may be significant; learning difficulties Abnormal facial features that include: Large-sized head and forehead Almond-shaped [dovemed.com]

eyes Eyebrows that meet at the center Low-set ears Upturned nose High-arched palate Small mouth Children are known to grow tall Feeding difficulties Abdominal pain and constipation [dovemed.com]

X-Linked Syndromic Intellectual Disability Type Schimke

bushy eyebrows XLD SLC9A6 #300243 CK SYNDROME Strabismus, epicanthal folds, upslanting palpebral fissures, almond-shaped eyes XLR NSDHL #300831 COCKAYNE SYNDROME Pigmentary [eyewiki.aao.org]

[…] intellectual disability (with severe speech impairment), a myxedematous appearance, dysmorphic facial features (including large head, synophrys, prominent supraorbital ridges, almond-shaped [mendelian.co]

X-Linked Syndromic Mental Retardation Type 11

bushy eyebrows XLD SLC9A6 #300243 CK SYNDROME Strabismus, epicanthal folds, upslanting palpebral fissures, almond-shaped eyes XLR NSDHL #300831 COCKAYNE SYNDROME Pigmentary [eyewiki.aao.org]

Deletion of chromosome 22; usually de novo but may be inherited in an autosomal dominant manner Cleft palate; congenital heart defect; speech delay; elongated face with almond-shaped [aafp.org]

Syndromic Microphthalmia Type 10

bushy eyebrows XLD SLC9A6 #300243 CK SYNDROME Strabismus, epicanthal folds, upslanting palpebral fissures, almond-shaped eyes XLR NSDHL #300831 COCKAYNE SYNDROME Pigmentary [eyewiki.aao.org]

bushy eyebrows/XLD/SLC9A6/#300243 CK SYNDROME/Strabismus, epicanthal folds, upslanting palpebral fissures, almond-shaped eyes/XLR/NSDHL/#300831 COCKAYNE SYNDROME/Pigmentary [eyewiki.org]

Enamel Hypoplasia - Cataracts - Aqueductal Stenosis

They also have unique pixie-like facial features--almond shaped eyes, oval ears, full lips, small chins, narrow faces, and broad mouths. [agentorangequiltoftears.com]

Galloway-Mowat Syndrome Type 5

The characteristic phases include an abnormally high but narrow forehead, ocular hypertelorism, almond-shaped eyes, pinched nose, large, and low-set ears with or without ear [sjkdt.org]

Chromosome 21q Deletion

The patient exhibited a shy demeanor, short statue, microcephaly and minor dysmorphic facial and body features, including long philtrum, frontal bossing, almond shaped eyes [spandidos-publications.com]

Glycoprotein 1A Deficiency

These may include inverted nipples, poor muscle tone, almond shaped eyes which are crossed, a large forehead, an unusual distribution of body fat, and abnormal genitals. [counsyl.com]

Autosomal Dominant Mental Retardation Type 21

Deletion of chromosome 22; usually de novo but may be inherited in an autosomal dominant manner Cleft palate; congenital heart defect; speech delay; elongated face with almond-shaped [aafp.org]

Congenital neurobehavioral disorder characterized by rounded face, low forehead, almond shaped eyes, squinting, hypogonadism, hypotonia, insatiable appetite leading to obesity [icd10data.com]

eyes; wide nose with hypoplastic alae nasi; small ears; slender, hyperextensible fingers Learning disabilities ± mild MR; psychiatric disorder in 10% High-resolution chromosome [aafp.org]

Osteogenesis Imperfecta Congenita - Microcephaly - Cataracts Syndrome

H3O - Hypotonia and weakness - Hypogonadism - Hyperphagia - Obesity + Short stature + Almond-shaped eyes + Small hands and feet with tapering of fingers + Hypopigmentation [brainscape.com]

bushy eyebrows XLD SLC9A6 #300243 CK SYNDROME Strabismus, epicanthal folds, upslanting palpebral fissures, almond-shaped eyes XLR NSDHL #300831 COCKAYNE SYNDROME Pigmentary [eyewiki.aao.org]